for Normal Lymphocyte Development -Converting Enzyme ADAM17 Is Required α Non-Cell Autonomous Expression of TNF-

VignaliNianyu Li, Kelli Boyd, Peter J. Dempsey and Dario A. A.http://www.jimmunol.org/content/178/7/4214J Immunol€2007; 178:4214-4221; ;Referenceshttp://www.jimmunol.org/content/178/7/4214.full#ref-list-1This article cites 43 articles, 19 of which you can access for free at: Subscriptionshttp://jimmunol.org/subscriptionsInformation about subscribing to The Journal of Immunology is online at: Permissionshttp://www.aai.org/ji/copyright.htmlSubmit copyright permission requests at: Email Alertshttp://jimmunol.org/cgi/alerts/etocReceive free email-alerts when new articles cite this article. Sign up at:

[1]  David D. Chaplin,et al.  Role of Lymphotoxin and the Type I TNF Receptor in the Formation of Germinal Centers , 1996, Science.

[2]  M. Cancro Peripheral B‐cell maturation: the intersection of selection and homeostasis , 2004, Immunological reviews.

[3]  H. Macdonald,et al.  Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes. , 2002, Immunity.

[4]  B. de Strooper,et al.  Cell–matrix interaction via CD44 is independently regulated by different metalloproteinases activated in response to extracellular Ca2+ influx and PKC activation , 2004, The Journal of cell biology.

[5]  David C. Lee,et al.  Defective valvulogenesis in HB‐EGF and TACE‐null mice is associated with aberrant BMP signaling , 2003, The EMBO journal.

[6]  A Cumano,et al.  A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE. , 2000, Molecular cell.

[7]  G. Rubin,et al.  KUZ, a Conserved Metalloprotease-Disintegrin Protein with Two Roles in Drosophila Neurogenesis , 1996, Science.

[8]  H. Lemke,et al.  CD30 Shedding from Karpas 299 Lymphoma Cells Is Mediated by TNF-α-Converting Enzyme1 , 2000, The Journal of Immunology.

[9]  G. Kollias,et al.  Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response , 1996, The Journal of experimental medicine.

[10]  C. Blobel,et al.  Adam Meets Eph: An ADAM Substrate Recognition Module Acts as a Molecular Switch for Ephrin Cleavage In trans , 2005, Cell.

[11]  Christin E Bland,et al.  Notch-induced Proteolysis and Nuclear Localization of the Delta Ligand* , 2003, The Journal of Biological Chemistry.

[12]  C. Blobel,et al.  Metalloproteases regulate T‐cell proliferation and effector function via LAG‐3 , 2007, The EMBO journal.

[13]  L. Klein,et al.  Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self , 2001, Nature Immunology.

[14]  Nicole Nelson,et al.  A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells , 1997, Nature.

[15]  S. Jarriault,et al.  Evidence for functional redundancy between C. elegans ADAM proteins SUP-17/Kuzbanian and ADM-4/TACE. , 2005, Developmental biology.

[16]  R. Black,et al.  Adamalysins: A Family of Metzincins Including TNF‐α Converting Enzyme (TACE) , 1999 .

[17]  S. Umland,et al.  ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23 , 2006, Nature Immunology.

[18]  C. Blobel,et al.  Stimulated Shedding of Vascular Cell Adhesion Molecule 1 (VCAM-1) Is Mediated by Tumor Necrosis Factor-α-converting Enzyme (ADAM 17)* , 2003, Journal of Biological Chemistry.

[19]  S. Nagata,et al.  Membrane-anchored CD40 is processed by the tumor necrosis factor-alpha-converting enzyme. Implications for CD40 signaling. , 2003, The Journal of biological chemistry.

[20]  E. Robey,et al.  Impairment of Thymocyte Development by Dominant-Negative Kuzbanian (ADAM-10) Is Rescued by the Notch Ligand, Delta-11 , 2005, The Journal of Immunology.

[21]  W. Pear,et al.  Regulation of lymphoid development, differentiation, and function by the Notch pathway. , 2005, Annual review of immunology.

[22]  D. Threadgill,et al.  Phenotypic Variation Resulting From a Deficiency of Epidermal Growth Factor Receptor in Mice Is Caused by Extensive Genetic Heterogeneity That Can Be Genetically and Molecularly Partitioned , 2004, Genetics.

[23]  B. de Strooper,et al.  The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts. , 2002, Human molecular genetics.

[24]  Susumu Tonegawa,et al.  RAG-1-deficient mice have no mature B and T lymphocytes , 1992, Cell.

[25]  Adil I. Khan,et al.  Leukocyte migration is regulated by L-selectin endoproteolytic release. , 2003, Immunity.

[26]  B. Fingleton,et al.  Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption. , 2000, The Journal of clinical investigation.

[27]  Mark S. Anderson,et al.  Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein , 2002, Science.

[28]  C. Blobel,et al.  Proteolytic Processing of Delta-like 1 by ADAM Proteases* , 2007, Journal of Biological Chemistry.

[29]  P. Schneider,et al.  BAFF AND APRIL: a tutorial on B cell survival. , 2003, Annual review of immunology.

[30]  P. Sideras,et al.  B Cell Development in the Spleen Takes Place in Discrete Steps and Is Determined by the Quality of B Cell Receptor–Derived Signals , 1999, The Journal of experimental medicine.

[31]  D. Selkoe,et al.  The Notch Ligands, Jagged and Delta, Are Sequentially Processed by α-Secretase and Presenilin/γ-Secretase and Release Signaling Fragments* , 2003, Journal of Biological Chemistry.

[32]  T. Nagasawa Microenvironmental niches in the bone marrow required for B-cell development , 2006, Nature Reviews Immunology.

[33]  J. Cyster,et al.  Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation. , 2001, Immunity.

[34]  Joseph D. Buxbaum,et al.  Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor* , 1998, The Journal of Biological Chemistry.

[35]  Masatsugu Hori,et al.  Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[36]  Raphael Kopan,et al.  A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1. , 2000, Molecular cell.

[37]  David C. Lee,et al.  TACE/ADAM17 Processing of EGFR Ligands Indicates a Role as a Physiological Convertase , 2003, Annals of the New York Academy of Sciences.

[38]  David C. Lee,et al.  Substrate specificity and inducibility of TACE (tumour necrosis factor alpha-converting enzyme) revisited: the Ala-Val preference, and induced intrinsic activity. , 2003, Biochemical Society symposium.

[39]  E. Robey,et al.  Notch signaling in lymphocyte development and function. , 2004, Current opinion in immunology.

[40]  E. Wagner,et al.  Strain-dependent epithelial defects in mice lacking the EGF receptor. , 1995, Science.

[41]  D. Warburton,et al.  TACE is required for fetal murine cardiac development and modeling. , 2003, Developmental biology.

[42]  R. Derynck,et al.  Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor , 1995, Nature.

[43]  David C. Lee,et al.  An essential role for ectodomain shedding in mammalian development. , 1998, Science.