Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor-related protein.
暂无分享,去创建一个
[1] J. Garcìa,et al. Neuronal ischemic injury: Light microscopy, ultrastructure and biochemistry , 1978, Acta Neuropathologica.
[2] C. Siao,et al. Cell Type-Specific Roles for Tissue Plasminogen Activator Released by Neurons or Microglia after Excitotoxic Injury , 2003, The Journal of Neuroscience.
[3] Richard G. W. Anderson,et al. LRP: Role in Vascular Wall Integrity and Protection from Atherosclerosis , 2003, Science.
[4] J. Serena,et al. Plasma Metalloproteinase-9 Concentration Predicts Hemorrhagic Transformation in Acute Ischemic Stroke , 2003, Stroke.
[5] I. Weissman,et al. Tissue plasminogen activator and NMDA receptor cleavage , 2003 .
[6] H. Birkedal‐Hansen,et al. Collagen Dissolution by Keratinocytes Requires Cell Surface Plasminogen Activation and Matrix Metalloproteinase Activity* , 2002, The Journal of Biological Chemistry.
[7] Michel Demeule,et al. High transcytosis of melanotransferrin (P97) across the blood–brain barrier , 2002, Journal of neurochemistry.
[8] A. Hand,et al. Storage and release of tissue plasminogen activator by sympathetic axons in resistance vessel walls. , 2002, Microvascular research.
[9] E. Lo,et al. Blood-Brain Barrier Disruption and Matrix Metalloproteinase-9 Expression During Reperfusion Injury: Mechanical Versus Embolic Focal Ischemia in Spontaneously Hypertensive Rats , 2002, Stroke.
[10] M. Chopp,et al. Adjuvant Treatment With Neuroserpin Increases the Therapeutic Window for Tissue-Type Plasminogen Activator Administration in a Rat Model of Embolic Stroke , 2002, Circulation.
[11] T. Coleman,et al. Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent. , 2002, The Journal of clinical investigation.
[12] Hartwig Wolburg,et al. Tight junctions of the blood-brain barrier: development, composition and regulation. , 2002, Vascular pharmacology.
[13] J. Herz,et al. Proteolytic Processing of Low Density Lipoprotein Receptor-related Protein Mediates Regulated Release of Its Intracellular Domain* , 2002, The Journal of Biological Chemistry.
[14] T. Hensch,et al. Permissive proteolytic activity for visual cortical plasticity , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[15] S. Coughlin. Protease-activated receptors in the cardiovascular system. , 2002, Cold Spring Harbor symposia on quantitative biology.
[16] H. Bock,et al. Lipoprotein receptors in the nervous system. , 2002, Annual review of biochemistry.
[17] P. Sonderegger,et al. Neuroserpin, a Neuroprotective Factor in Focal Ischemic Stroke , 2001, Molecular and Cellular Neuroscience.
[18] M. Fini,et al. Effects of Matrix Metalloproteinase-9 Gene Knock-Out on the Proteolysis of Blood–Brain Barrier and White Matter Components after Cerebral Ischemia , 2001, The Journal of Neuroscience.
[19] P. Bornstein,et al. The Low Density Lipoprotein Receptor-related Protein Modulates Levels of Matrix Metalloproteinase 9 (MMP-9) by Mediating Its Cellular Catabolism* , 2001, The Journal of Biological Chemistry.
[20] Alain Buisson,et al. The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling , 2001, Nature Medicine.
[21] M. Fini,et al. Role for Matrix Metalloproteinase 9 after Focal Cerebral Ischemia: Effects of Gene Knockout and Enzyme Inhibition with BB-94 , 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[22] T. Coleman,et al. HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY Neuroserpin reduces cerebral infarct volume and protects neurons from , 2022 .
[23] L. Badimón,et al. LDL receptor-related protein mediates uptake of aggregated LDL in human vascular smooth muscle cells. , 2000, Arteriosclerosis, thrombosis, and vascular biology.
[24] D. Holtzman,et al. Role of Tissue Plasminogen Activator Receptor LRP in Hippocampal Long-Term Potentiation , 2000, The Journal of Neuroscience.
[25] P. Carmeliet,et al. Tissue plasminogen activator (tPA) deficiency exacerbates cerebrovascular fibrin deposition and brain injury in a murine stroke model: studies in tPA-deficient mice and wild-type mice on a matched genetic background. , 1999, Arteriosclerosis, thrombosis, and vascular biology.
[26] P. Carmeliet,et al. Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice. , 1999, Circulation.
[27] J. Koh,et al. Nonproteolytic neuroprotection by human recombinant tissue plasminogen activator. , 1999, Science.
[28] T. Betsuyaku,et al. Neutrophil emigration in the lungs, peritoneum, and skin does not require gelatinase B. , 1999, American journal of respiratory cell and molecular biology.
[29] L. Rubin,et al. The cell biology of the blood-brain barrier. , 1999, Annual review of neuroscience.
[30] C. Sobey,et al. Activation of protease-activated receptor-2 (PAR-2) elicits nitric oxide-dependent dilatation of the basilar artery in vivo. , 1998, Stroke.
[31] Gabriele Bergers,et al. MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes , 1998, Cell.
[32] G. Bu,et al. Receptor-associated protein: a specialized chaperone and antagonist for members of the LDL receptor gene family. , 1998, Current opinion in lipidology.
[33] S. Lipton,et al. Tissue plasminogen activator (tPA) increase neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice , 1998, Nature Medicine.
[34] George Paxinos,et al. The Mouse Brain in Stereotaxic Coordinates , 2001 .
[35] L. Fenart,et al. A New Function for the LDL Receptor: Transcytosis of LDL across the Blood–Brain Barrier , 1997, The Journal of cell biology.
[36] T. Bugge,et al. Loss of Fibrinogen Rescues Mice from the Pleiotropic Effects of Plasminogen Deficiency , 1996, Cell.
[37] Gary A. Rosenberg,et al. Proteolytic Cascade Enzymes Increase in Focal Cerebral Ischemia in Rat , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[38] P. Bickford,et al. Tissue Plasminogen Activator Induction in Purkinje Neurons After Cerebellar Motor Learning , 1995, Science.
[39] Joseph P. Broderick,et al. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. , 1995 .
[40] William G. Stetler-Stevenson,et al. Tumor necrosis factor-α-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window , 1995, Brain Research.
[41] Sidney Strickland,et al. Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator , 1995, Nature.
[42] A. M. Romanic,et al. Extracellular Matrix‐Degrading Proteinases in the Nervous System , 1994, Brain pathology.
[43] Eric R. Kandel,et al. Tissue-plasminogen activator is induced as an immediate–early gene during seizure, kindling and long-term potentiation , 1993, Nature.
[44] A. Schwartz,et al. Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[45] O. Myklebost,et al. Surface location and high affinity for calcium of a 500‐kd liver membrane protein closely related to the LDL‐receptor suggest a physiological role as lipoprotein receptor. , 1988, The EMBO journal.
[46] L. Iversen,et al. The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[47] Baker Rn,et al. The Movement of Exogenous Protein in Experimental Cerebral Edema An electron microscopic study after freeze-injury , 1971 .
[48] P. Cancilla,et al. THE MOVEMENT OF EXOGENOUS PROTEIN IN EXPERIMENTAL CEREBRAL EDEMA An electron microscopic study after freeze‐injury , 1971, Journal of neuropathology and experimental neurology.