Mesenchymal stem cells from umbilical cord matrix, adipose tissue and bone marrow exhibit different capability to suppress peripheral blood B, natural killer and T cells

[1]  G. Gilkeson,et al.  Allogenic Mesenchymal Stem Cell Transplantation Ameliorates Nephritis in Lupus Mice via Inhibition of B-Cell Activation , 2013, Cell transplantation.

[2]  E. Haddad,et al.  Cord-blood-derived mesenchymal stromal cells downmodulate CD4+ T-cell activation by inducing IL-10-producing Th1 cells. , 2013, Stem cells and development.

[3]  Z. Zhao,et al.  The Different Immunoregulatory Functions on Dendritic Cells between Mesenchymal Stem Cells Derived from Bone Marrow of Patients with Low-Risk or High-Risk Myelodysplastic Syndromes , 2013, PloS one.

[4]  X. Luan,et al.  Human placenta-derived mesenchymal stem cells suppress T cell proliferation and support the culture expansion of cord blood CD34⁺ cells: a comparison with human bone marrow-derived mesenchymal stem cells. , 2013, Tissue & cell.

[5]  F. Djouad,et al.  Mesenchymal stem cells repress Th17 molecular program through the PD-1 pathway , 2012, Journal of Translational Medicine.

[6]  B. Akgül,et al.  Aggregatibacter actinomycetemcomitans GroEL Protein Promotes Conversion of Human CD4+ T Cells into IFNγ IL10 Producing Tbet+ Th1 Cells , 2012, PloS one.

[7]  M. Toungouz,et al.  Characterization and functionality of the CD200-CD200R system during mesenchymal stromal cell interactions with T-lymphocytes. , 2012, Immunology letters.

[8]  H. Tse,et al.  Mesenchymal stem cells derived from human induced pluripotent stem cells modulate T-cell phenotypes in allergic rhinitis , 2012, Allergy.

[9]  P. Laranjeira,et al.  Immunophenotypic Characterization of Normal Bone Marrow Stem Cells , 2012 .

[10]  E. Lombardo,et al.  Human adipose-derived stem cells impair natural killer cell function and exhibit low susceptibility to natural killer-mediated lysis. , 2012, Stem cells and development.

[11]  W. Weimar,et al.  On the interactions between mesenchymal stem cells and regulatory T cells for immunomodulation in transplantation , 2012, Front. Immun..

[12]  J. Grinyó,et al.  Immunomodulatory Effect of Mesenchymal Stem Cells on B Cells , 2012, Front. Immun..

[13]  B. Xia,et al.  CD4+T Cells: Differentiation and Functions , 2012, Clinical & developmental immunology.

[14]  A. Venditti,et al.  CD69 is independently prognostic in chronic lymphocytic leukemia: a comprehensive clinical and biological profiling study , 2012, Haematologica.

[15]  Lieping Chen,et al.  B7-H4 Treatment of T Cells Inhibits ERK, JNK, p38, and AKT Activation , 2012, PloS one.

[16]  K. Pramanik,et al.  Immunomodulatory Properties of Mesenchymal Stem Cells: Cytokines and Factors , 2012, American journal of reproductive immunology.

[17]  Yuhong Yang,et al.  TGF‐β signaling via Smad4 drives IL‐10 production in effector Th1 cells and reduces T‐cell trafficking in EAE , 2011, European journal of immunology.

[18]  S. Morbelli,et al.  Mesenchymal stem cells impair in vivo T-cell priming by dendritic cells , 2011, Proceedings of the National Academy of Sciences.

[19]  S. Chouaib,et al.  Human mesenchymal stem cells derived from induced pluripotent stem cells down-regulate NK-cell cytolytic machinery. , 2011, Blood.

[20]  T. Ritter,et al.  Mesenchymal stem cell effects on T-cell effector pathways , 2011, Stem Cell Research & Therapy.

[21]  M. Yen,et al.  Immunomodulatory properties of human adult and fetal multipotent mesenchymal stem cells , 2011, Journal of Biomedical Science.

[22]  E. Andreeva,et al.  Subpopulation Composition and Activation of T Lymphocytes during Coculturing with Mesenchymal Stromal Cells in Medium with Different O2 Content , 2011, Bulletin of Experimental Biology and Medicine.

[23]  Kazuya Sato,et al.  Mesenchymal stromal cells inhibit Th17 but not regulatory T-cell differentiation. , 2011, Cytotherapy.

[24]  M. Zago,et al.  Mesenchymal stromal cells up-regulate CD39 and increase adenosine production to suppress activated T-lymphocytes. , 2011, Stem cell research.

[25]  K. Klotz,et al.  Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity , 2011, Cancer Immunology, Immunotherapy.

[26]  Z. Madeja,et al.  Genetically modified adipose tissue-derived mesenchymal stem cells overexpressing CXCR4 display increased motility, invasiveness, and homing to bone marrow of NOD/SCID mice. , 2011, Experimental hematology.

[27]  A. Durrbach,et al.  Long-Lasting Inhibitory Effects of Fetal Liver Mesenchymal Stem Cells on T-Lymphocyte Proliferation , 2011, PloS one.

[28]  E. Chernykh,et al.  Multiplex Analysis of Cytokines, Chemokines, Growth Factors, MMP-9 and TIMP-1 Produced by Human Bone Marrow, Adipose Tissue, and Placental Mesenchymal Stromal Cells , 2011, Bulletin of Experimental Biology and Medicine.

[29]  F. Carrión,et al.  Opposing effect of mesenchymal stem cells on Th1 and Th17 cell polarization according to the state of CD4+ T cell activation. , 2011, Immunology letters.

[30]  M. van Griensven,et al.  Human mesenchymal stem cells from adipose tissue and amnion influence T-cells depending on stimulation method and presence of other immune cells. , 2011, Stem cells and development.

[31]  Xia Li,et al.  Transplantation of placenta-derived mesenchymal stem cells in type 2 diabetes: a pilot study , 2011, Frontiers of medicine.

[32]  B. Cochran STAT3 (signal transducer and activator of transcription 3) , 2011 .

[33]  Shinn-Zong Lin,et al.  Mesenchymal Stem Cells , 2011, Cell transplantation.

[34]  N. Câmara,et al.  Immune regulatory properties of multipotent mesenchymal stromal cells: Where do we stand? , 2011, World journal of stem cells.

[35]  A. Caplan,et al.  Mesenchymal stem cells: mechanisms of inflammation. , 2011, Annual review of pathology.

[36]  Gabriel Courties,et al.  IL-6-Dependent PGE2 Secretion by Mesenchymal Stem Cells Inhibits Local Inflammation in Experimental Arthritis , 2010, PloS one.

[37]  A. Cutler,et al.  Umbilical Cord-Derived Mesenchymal Stromal Cells Modulate Monocyte Function to Suppress T Cell Proliferation , 2010, The Journal of Immunology.

[38]  R. Yañez,et al.  Prostaglandin E2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells. , 2010, Experimental cell research.

[39]  R. Handgretinger,et al.  Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells. , 2010, Blood.

[40]  T. Ritter,et al.  Immunological aspects of allogeneic mesenchymal stem cell therapies. , 2010, Human gene therapy.

[41]  M. Toungouz,et al.  Modulated expression of adhesion molecules and galectin-1: role during mesenchymal stromal cell immunoregulatory functions. , 2010, Experimental hematology.

[42]  A. Martini,et al.  Interferon-γ-dependent inhibition of B cell activation by bone marrow-derived mesenchymal stem cells in a murine model of systemic lupus erythematosus. , 2010, Arthritis and rheumatism.

[43]  M. Toungouz,et al.  Adipose-tissue-derived and Wharton's jelly-derived mesenchymal stromal cells suppress lymphocyte responses by secreting leukemia inhibitory factor. , 2010, Tissue engineering. Part A.

[44]  P. Menasché,et al.  Galectin-1 and semaphorin-3A are two soluble factors conferring T-cell immunosuppression to bone marrow mesenchymal stem cell. , 2010, Stem cells and development.

[45]  C. Jorgensen,et al.  Mesenchymal Stem Cells Inhibit Human Th17 Cell Differentiation and Function and Induce a T Regulatory Cell Phenotype , 2010, The Journal of Immunology.

[46]  Steven J. Greco,et al.  Mesenchymal Stem Cells Protect Breast Cancer Cells through Regulatory T Cells: Role of Mesenchymal Stem Cell-Derived TGF-β , 2010, The Journal of Immunology.

[47]  Xiaodong Chen,et al.  Mesenchymal stem cells: a new strategy for immunosuppression and tissue repair , 2010, Cell Research.

[48]  A. Boudabous,et al.  Evidence for the Involvement of Galectin‐3 in Mesenchymal Stem Cell Suppression of Allogeneic T‐Cell Proliferation , 2010, Scandinavian journal of immunology.

[49]  F. Djouad,et al.  Immunosuppression by mesenchymal stem cells: mechanisms and clinical applications , 2010, Stem Cell Research & Therapy.

[50]  Shilpa Shankar,et al.  Pro-Inflammatory Cytokines, IFNγ and TNFα, Influence Immune Properties of Human Bone Marrow and Wharton Jelly Mesenchymal Stem Cells Differentially , 2010, PloS one.

[51]  X. Luan,et al.  The negative co-signaling molecule b7-h4 is expressed by human bone marrow-derived mesenchymal stem cells and mediates its T-cell modulatory activity. , 2010, Stem cells and development.

[52]  Cláudia Lobato da Silva,et al.  Ex vivo expansion of human mesenchymal stem cells: A more effective cell proliferation kinetics and metabolism under hypoxia , 2009, Journal of cellular physiology.

[53]  C. Thiemermann,et al.  Mesenchymal Stromal Cells: Current Understanding and Clinical Status , 2009, Stem cells.

[54]  A. Reinisch,et al.  Isolation and animal serum free expansion of human umbilical cord derived mesenchymal stromal cells (MSCs) and endothelial colony forming progenitor cells (ECFCs). , 2009, Journal of visualized experiments : JoVE.

[55]  Yang Li,et al.  [Effect of mesenchymal stem cells on expression of CD69 in cord blood CIK/NK cells and quantity ratio of T regulatory cells in CIK/NK cell culture]. , 2009, Zhongguo shi yan xue ye xue za zhi.

[56]  Zhenping Chen,et al.  Fetal BM‐derived mesenchymal stem cells promote the expansion of human Th17 cells, but inhibit the production of Th1 cells , 2009, European journal of immunology.

[57]  Min-jung Park,et al.  Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10 , 2009, Experimental & Molecular Medicine.

[58]  S. Itakura,et al.  Mesenchymal stem cells suppress B-cell terminal differentiation. , 2009, Experimental hematology.

[59]  José F. M. Morgado,et al.  Quantification and immunophenotypic characterization of bone marrow and umbilical cord blood mesenchymal stem cells by multicolor flow cytometry. , 2009, Transplantation proceedings.

[60]  M. Yen,et al.  Brief Report—Human Embryonic Stem Cell‐Derived Mesenchymal Progenitors Possess Strong Immunosuppressive Effects Toward Natural Killer Cells as Well as T Lymphocytes , 2009, Stem cells.

[61]  S. Feng,et al.  Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury , 2009, Chinese medical journal.

[62]  M. Tremblay,et al.  Mesenchymal stromal cell-derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction. , 2008, Blood.

[63]  J. Ryan,et al.  Cell contact, prostaglandin E2 and transforming growth factor beta 1 play non‐redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+ regulatory T cells , 2008, Clinical and experimental immunology.

[64]  B. Blanco,et al.  The effect of mesenchymal stem cells on the viability, proliferation and differentiation of B-lymphocytes , 2008, Haematologica.

[65]  H. Klingemann,et al.  Mesenchymal Stem Cells – Sources and Clinical Applications , 2008, Transfusion Medicine and Hemotherapy.

[66]  Mohamed H. Sayegh,et al.  Immunomodulation by Mesenchymal Stem Cells , 2008, Diabetes.

[67]  E. Shankar,et al.  Relationship between T-lymphocyte cytokine levels and sero-response to hepatitis B vaccines. , 2008, World journal of gastroenterology.

[68]  S. Kyurkchiev,et al.  Mesenchymal stem cells from human bone marrow or adipose tissue differently modulate mitogen‐stimulated B‐cell immunoglobulin production in vitro , 2008, Cell biology international.

[69]  David M. Conrad,et al.  Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review). , 2008, International journal of oncology.

[70]  R. Zhao,et al.  Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide. , 2008, Cell stem cell.

[71]  L. Moretta,et al.  Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2. , 2008, Blood.

[72]  N. Rouas-Freiss,et al.  Human Leukocyte Antigen‐G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+ Regulatory T Cells , 2008, Stem cells.

[73]  L. Cosmi,et al.  Toll‐Like Receptors 3 and 4 Are Expressed by Human Bone Marrow‐Derived Mesenchymal Stem Cells and Can Inhibit Their T‐Cell Modulatory Activity by Impairing Notch Signaling , 2008, Stem cells.

[74]  A. Nauta,et al.  Immunomodulatory properties of mesenchymal stromal cells. , 2007, Blood.

[75]  Giselle Chamberlain,et al.  Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing , 2007, Stem cells.

[76]  L. Fouillard,et al.  Immunosuppressive Effects of Mesenchymal Stem Cells: Involvement of HLA-G , 2007, Transplantation.

[77]  A. Poggi,et al.  Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction. , 2007, Haematologica.

[78]  Lingyun Sun,et al.  Polarization of T Lymphocytes Is Regulated by Mesenchymal Stem Cells in NZBWF1 and BALB/c Mice , 2007, International Journal of Molecular Sciences.

[79]  O. Ringdén,et al.  Mesenchymal Stem Cells Stimulate Antibody Secretion in Human B Cells , 2007, Scandinavian journal of immunology.

[80]  R. Tuan,et al.  Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation , 2007, Arthritis research & therapy.

[81]  G. Prendergast,et al.  Indoleamine 2,3-dioxygenase in immune suppression and cancer. , 2007, Current cancer drug targets.

[82]  A. Cometa,et al.  Human mesenchymal stem cells inhibit antibody production induced in vitro by allostimulation. , 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[83]  X. Chen,et al.  Mesenchymal stem cells in immunoregulation , 2006, Immunology and cell biology.

[84]  J. V. van Laar,et al.  Adult stem cells in the treatment of autoimmune diseases. , 2006, Rheumatology.

[85]  A. Uccelli,et al.  Immunoregulatory function of mesenchymal stem cells , 2006, European journal of immunology.

[86]  M. Faronato,et al.  Semaphorin-3A is expressed by tumor cells and alters T-cell signal transduction and function. , 2006, Blood.

[87]  S. Perez,et al.  Interactions Between Human Mesenchymal Stem Cells and Natural Killer Cells , 2006, Stem cells.

[88]  G. Mancardi,et al.  Mesenchymal stem cells ameliorate experimental autoimmune encephalomyelitis inducing T-cell anergy. , 2005, Blood.

[89]  Frank P Barry,et al.  Mesenchymal stem cells avoid allogeneic rejection , 2005, Journal of Inflammation.

[90]  R. Cancedda,et al.  Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway , 2005, European journal of immunology.

[91]  O. Ringdén,et al.  Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms. , 2005, Experimental cell research.

[92]  O. Ringdén,et al.  Mesenchymal Stem Cells Inhibit the Expression of CD25 (Interleukin‐2 Receptor) and CD38 on Phytohaemagglutinin‐Activated Lymphocytes , 2004, Scandinavian journal of immunology.

[93]  O. Ringdén,et al.  Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells , 2003, Transplantation.

[94]  M. Krampera,et al.  Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. , 2003, Blood.

[95]  E. Guinan,et al.  Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation , 2003, Transplantation.

[96]  J. Spivak Polycythemia vera: myths, mechanisms, and management. , 2002, Blood.

[97]  C. Carlo-Stella,et al.  Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. , 2002, Blood.

[98]  G. Sukhikh,et al.  Mesenchymal Stem Cells , 2002, Bulletin of Experimental Biology and Medicine.

[99]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[100]  J. Tomaz,et al.  Functional aspects of cord blood lymphocytes response to polyclonal and allogeneic activation. , 1998, Bone marrow transplantation.

[101]  N. Pellis,et al.  Suppressed PHA activation of T lymphocytes in simulated microgravity is restored by direct activation of protein kinase C , 1998, Journal of leukocyte biology.

[102]  P. Simms,et al.  Utility of flow cytometric detection of CD69 expression as a rapid method for determining poly- and oligoclonal lymphocyte activation , 1996, Clinical and diagnostic laboratory immunology.

[103]  G. Trinchieri,et al.  The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells , 1996, The Journal of experimental medicine.

[104]  M. Norcross,et al.  Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-gamma of lipopolysaccharide-inducible p35 and p40 genes. , 1995, Blood.

[105]  A. Singer,et al.  Similar co-stimulation requirements of CD4+ and CD8+ primary T helper cells: role of IL-1 and IL-6 in inducing IL-2 secretion and subsequent proliferation. , 1992, International immunology.

[106]  M. Loeffler,et al.  Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. , 1990, Development.

[107]  L. Davis,et al.  Comparative effects of tumor necrosis factor-alpha and IL-1 beta on mitogen-induced T cell activation. , 1988, Journal of immunology.

[108]  P. Lipsky,et al.  Inhibition of human B cell responsiveness by prostaglandin E2. , 1987, Journal of immunology.

[109]  P. Lipsky,et al.  Regulation of human B cell proliferation by prostaglandin E2. , 1984, Journal of immunology.

[110]  Jacques Galipeau,et al.  Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation. , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

[111]  M. Kolácková,et al.  CD200/CD200R paired potent inhibitory molecules regulating immune and inflammatory responses; Part I: CD200/CD200R structure, activation, and function. , 2012, Acta medica.

[112]  M. Toungouz,et al.  Mesenchymal stromal cells use PGE2 to modulate activation and proliferation of lymphocyte subsets: Combined comparison of adipose tissue, Wharton's Jelly and bone marrow sources. , 2010, Cellular immunology.

[113]  P. Martiat,et al.  Mesenchymal stromal cells promote or suppress the proliferation of T lymphocytes from cord blood and peripheral blood: the importance of low cell ratio and role of interleukin-6. , 2009, Cytotherapy.

[114]  H. Koo,et al.  Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues. , 2009, Cellular immunology.

[115]  L. Moretta,et al.  T.6. Mesenchymal Stem Cells Inhibit Natural Killer Cell Proliferation, Cytotoxicity and Cytokine Production: Role of Indoleamine 2,3-Dioxygenase and Prostaglandin E2 , 2009 .

[116]  R. Ramasamy,et al.  The immunosuppressive effects of human bone marrow-derived mesenchymal stem cells target T cell proliferation but not its effector function. , 2008, Cellular immunology.

[117]  J. Stagg Immune regulation by mesenchymal stem cells: two sides to the coin. , 2007, Tissue antigens.

[118]  C. Briani,et al.  Polyneuropathy, organomegaly, endocrinopathy, M protein, skin changes: not always a POEMS syndrome. , 2006, Haematologica.

[119]  G. Sukhikh,et al.  Differentiation potential of mesenchymal stem cells of different origin , 2006, Bulletin of Experimental Biology and Medicine.

[120]  F. Benvenuto,et al.  Human mesenchymal stem cells modulate B-cell functions. , 2006, Blood.

[121]  K. Kokame,et al.  von Willebrand factor cleavage ADAMTS-13 cysteine-rich / spacer domains are functionally essential for , 2003 .

[122]  F. Guilak,et al.  Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. , 2003, Cytotherapy.

[123]  生越喬二 HLA(human leukocyte antigen) , 2002 .

[124]  J. Ceuppens,et al.  Accessory cell-derived helper signals in human T-cell activation with phytohemagglutinin: induction of interleukin 2-responsiveness by interleukin 6, and production of interleukin 2 by interleukin 1 [corrected]. , 1990, Cytokine.