Decreased serum levels of thioredoxin in patients with coronary artery disease plus hyperhomocysteinemia is strongly associated with the disease severity.

[1]  J. Stamler,et al.  Protein denitrosylation: enzymatic mechanisms and cellular functions , 2009, Nature Reviews Molecular Cell Biology.

[2]  A. Holmgren,et al.  Penultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium‐deficient rat liver , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[3]  J. Yodoi,et al.  Thioredoxin in coronary culprit lesions: possible relationship to oxidative stress and intraplaque hemorrhage. , 2008, Atherosclerosis.

[4]  Qingbo Xu,et al.  Regulatory role of thioredoxin in homocysteine‐induced monocyte chemoattractant protein‐1 secretion in monocytes/macrophages , 2008, FEBS letters.

[5]  Hwa-young Kim,et al.  Thioredoxin as a reducing agent for mammalian methionine sulfoxide reductases B lacking resolving cysteine. , 2008, Biochemical and biophysical research communications.

[6]  J. Loscalzo,et al.  Homocysteine and glutathione peroxidase-1. , 2007, Antioxidants & redox signaling.

[7]  Charles H Williams,et al.  The relationship of the redox potentials of thioredoxin and thioredoxin reductase from Drosophila melanogaster to the enzymatic mechanism: reduced thioredoxin is the reductant of glutathione in Drosophila. , 2007, Biochemistry.

[8]  J. D. de Lemos,et al.  Statins and cardiovascular risk reduction in patients with chronic kidney disease and end-stage renal failure. , 2007, American heart journal.

[9]  P. Svensson,et al.  Oxidized LDL induces a coordinated up-regulation of the glutathione and thioredoxin systems in human macrophages. , 2006, Atherosclerosis.

[10]  S. Tyagi,et al.  Mechanisms of homocysteine-induced oxidative stress. , 2005, American journal of physiology. Heart and circulatory physiology.

[11]  J. Yodoi,et al.  Increased plasma levels of thioredoxin in patients with glucose intolerance. , 2005, Internal medicine.

[12]  W. Jin,et al.  Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells , 2005, Experimental & Molecular Medicine.

[13]  A. Holmgren,et al.  Thiol redox control via thioredoxin and glutaredoxin systems. , 2005, Biochemical Society transactions.

[14]  M. Fernando,et al.  Induction of thioltransferase and thioredoxin/thioredoxin reductase systems in cultured porcine lenses under oxidative stress. , 2005, Investigative ophthalmology & visual science.

[15]  R. Banerjee,et al.  Homocysteine and redox signaling. , 2005, Antioxidants & redox signaling.

[16]  Yong J. Lee,et al.  Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1. , 2003, The Biochemical journal.

[17]  J. Yodoi,et al.  Increased plasma thioredoxin in patients with acute myocardial infarction , 2002, Clinical cardiology.

[18]  K. Das,et al.  Thioredoxin, a singlet oxygen quencher and hydroxyl radical scavenger: redox independent functions. , 2000, Biochemical and biophysical research communications.

[19]  Elias S. J. Arnér,et al.  Physiological functions of thioredoxin and thioredoxin reductase. , 2000, European journal of biochemistry.

[20]  T. Horie,et al.  Thioredoxin negatively regulates p38 MAP kinase activation and IL-6 production by tumor necrosis factor-alpha. , 1999, Biochemical and biophysical research communications.

[21]  J. M. May,et al.  Reduction of Dehydroascorbate to Ascorbate by the Selenoenzyme Thioredoxin Reductase* , 1997, The Journal of Biological Chemistry.

[22]  G. Powis,et al.  Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer. , 1996, Structure.

[23]  M. Cha,et al.  Thioredoxin-linked peroxidase from human red blood cell: evidence for the existence of thioredoxin and thioredoxin reductase in human red blood cell. , 1995, Biochemical and biophysical research communications.

[24]  M. Hamberg,et al.  Human Thioredoxin Reductase Directly Reduces Lipid Hydroperoxides by NADPH and Selenocystine Strongly Stimulates the Reaction via Catalytically Generated Selenols(*) , 1995, The Journal of Biological Chemistry.

[25]  M. Malinow.  Homocyst(e)ine and arterial occlusive diseases , 1994, Journal of internal medicine.

[26]  G. Gensini,et al.  A more meaningful scoring system for determining the severity of coronary heart disease. , 1983, The American journal of cardiology.

[27]  A. Holmgren,et al.  Mammalian thioredoxin reductases as hydroperoxide reductases. , 2002, Methods in enzymology.

[28]  B. Sahaf,et al.  Secretion of 10-kDa and 12-kDa thioredoxin species from blood monocytes and transformed leukocytes. , 2000, Antioxidants & redox signaling.

[29]  Elga,et al.  PLASMA HOMOCYSTEINE LEVELS AND MORTALITY IN PATIENTS WITH CORONARY ARTERY DISEASE , 2000 .