The effect of adding intrathecal magnesium sulphate to bupivacaine–fentanyl spinal anaesthesia

Background:  The addition of intrathecal (IT) magnesium to spinal fentanyl prolongs the duration of spinal analgesia for vaginal delivery. In this prospective, randomized, double‐blind, controlled study, we investigated the effect of adding IT magnesium sulphate to bupivacaine–fentanyl spinal anaesthesia.

[1]  A. Koroglu,et al.  Effects of S(+) ketamine added to bupivacaine for spinal anaesthesia for prostate surgery in elderly patients , 2004, European journal of anaesthesiology.

[2]  Richard Taylor,et al.  Intrathecal Morphine for Postoperative Analgesia: A Randomized, Controlled, Dose-Ranging Study After Hip and Knee Arthroplasty , 2003, Anesthesia and analgesia.

[3]  J. Kroin,et al.  Intrathecal Magnesium Prolongs Fentanyl Analgesia: A Prospective, Randomized, Controlled Trial , 2002, Anesthesia and analgesia.

[4]  Dong-Chan Kim,et al.  Magnesium Sulfate Does Not Reduce Postoperative Analgesic Requirements , 2001, Anesthesiology.

[5]  J. Kroin,et al.  Magnesium Sulfate Potentiates Morphine Antinociception at the Spinal Level , 2000, Anesthesia and analgesia.

[6]  B. Sibai,et al.  MAGNESIUM SULFATE THERAPY IN PREECLAMPSIA AND ECLAMPSIA , 1998, Obstetrics and gynecology.

[7]  L. Arendt-Nielsen,et al.  Sensory Changes and Pain After Abdominal Hysterectomy: A Comparison of Anesthetic Supplementation with Fentanyl Versus Magnesium or Ketamine , 1998, Anesthesia and analgesia.

[8]  M. Serpell,et al.  Intrathecal Anesthesia With Ketamine , 1997, Regional Anesthesia & Pain Medicine.

[9]  A. Dickenson NMDA receptor antagonists: interactions with opioids , 1997, Acta anaesthesiologica Scandinavica.

[10]  M. Tramèr,et al.  Role of Magnesium Sulfate in Postoperative Analgesia , 1996, Anesthesiology.

[11]  D. Price,et al.  Mechanisms of hyperalgesian and morphine tolerance: a current view of their possible interactions , 1995, Pain.

[12]  G. Bennett,et al.  Magnesium suppresses neuropathic pain responses in rats via a spinal site of action , 1994, Brain Research.

[13]  G. Koski,et al.  Intrathecal Magnesium Sulfate Protects the Spinal Cord from Ischemic Injury during Thoracic Aortic Cross-clamping , 1994, Anesthesiology.

[14]  M. Ashburn,et al.  Respiratory-related critical events with intravenous patient-controlled analgesia. , 1994, The Clinical journal of pain.

[15]  T. Yaksh,et al.  Studies on the spinal interaction of morphine and the NMDA antagonist MK-801 on the hyperesthesia observed in a rat model of sciatic mononeuropathy , 1992, Neuroscience Letters.

[16]  L. Merlini,et al.  The incidence of narcotic-induced emesis. , 1991, Journal of pain and symptom management.

[17]  G. Sharwood-Smith,et al.  Profound respiratory depression after extradural fentanyl. , 1990, British journal of anaesthesia.

[18]  D. Niv,et al.  Ventilatory effects of subarachnoid fentanyl in the elderly , 1990, Anaesthesia.

[19]  A. Ravalia,et al.  Respiratory depression and spinal opioids , 1989, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[20]  L. Nowak,et al.  Electrophysiological studies of NMDA receptors , 1987, Trends in Neurosciences.

[21]  Lejuste Mj Inadvertant intrathecal administration of magnesium sulfate. , 1985 .

[22]  M. Lejuste Inadvertant intrathecal administration of magnesium sulfate. , 1985, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.