Recombinant human bone morphogenetic protein is a valid alternative to autologous bone graft for long bone non-unions: a systematic review and meta-analysis.

[1]  S. Amler,et al.  Effect of Bone Morphogenetic Protein-2 in the Treatment of Long Bone Non-Unions , 2021, Journal of clinical medicine.

[2]  Christopher Lee,et al.  Surgical Tips and Tricks for Distal Femur Plating. , 2021, The Journal of the American Academy of Orthopaedic Surgeons.

[3]  E. Mayo-Wilson,et al.  The PRISMA 2020 statement: An updated guideline for reporting systematic reviews , 2021, PLoS medicine.

[4]  T. Ruppar,et al.  Meta-analysis: How to quantify and explain heterogeneity? , 2020, European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology.

[5]  A. Reddi,et al.  Discovery of Bone Morphogenetic Proteins - A Historical Perspective. , 2020, Bone.

[6]  W. Huf,et al.  Complication rate after operative treatment of three- and four-part fractures of the proximal humerus: locking plate osteosynthesis versus proximal humeral nail , 2020, European Journal of Trauma and Emergency Surgery.

[7]  P. Giannoudis,et al.  Femoral non-union above a fused knee: Successful treatment with exchange nailing and intramedullary delivery of bone morphogenetic protein , 2020, Trauma case reports.

[8]  Lifeng Lin,et al.  The trim-and-fill method for publication bias: practical guidelines and recommendations based on a large database of meta-analyses , 2019, Medicine.

[9]  P. Giannoudis,et al.  The ‘diamond concept’ for long bone non-union management , 2019, Journal of Orthopaedics and Traumatology.

[10]  B. Gabbe,et al.  Incidence, Costs and Predictors of Non-Union, Delayed Union and Mal-Union Following Long Bone Fracture , 2018, International journal of environmental research and public health.

[11]  G. Schmidmaier,et al.  Comparison of the clinical effectiveness of Bone Morphogenic Protein (BMP) -2 and -7 in the adjunct treatment of lower limb nonunions. , 2018, Orthopaedics & traumatology, surgery & research : OTSR.

[12]  Lifeng Lin,et al.  Quantifying publication bias in meta‐analysis , 2018, Biometrics.

[13]  Xinzhi Li,et al.  Application of BMP-2 bone graftting material in nonunion after femoral intramedullary nail , 2018 .

[14]  J. Friederichs,et al.  Long-term outcome following additional rhBMP-7 application in revision surgery of aseptic humeral, femoral, and tibial shaft nonunion , 2017, BMC Musculoskeletal Disorders.

[15]  A. Simpson,et al.  The risk of non-union per fracture: current myths and revised figures from a population of over 4 million adults , 2017, Acta orthopaedica.

[16]  V. Agrawal,et al.  A review on carrier systems for bone morphogenetic protein-2. , 2017, Journal of biomedical materials research. Part B, Applied biomaterials.

[17]  Gopal Shankar Krishnakumar,et al.  Clinical application of bone morphogenetic proteins for bone healing: a systematic review , 2017, International Orthopaedics.

[18]  S. Manochantr,et al.  Bone morphogenetic protein-2 enhances the osteogenic differentiation capacity of mesenchymal stromal cells derived from human bone marrow and umbilical cord , 2017, International journal of molecular medicine.

[19]  P. Augat,et al.  Comparative study suggests that human bone morphogenetic proteins have no influence on the outcome of operative treatment of aseptic clavicle non-unions , 2016, International Orthopaedics.

[20]  J. Friederichs,et al.  The missing effect of human recombinant Bone Morphogenetic Proteins BMP-2 and BMP-7 in surgical treatment of aseptic forearm nonunion. , 2016, Injury.

[21]  M. McKee,et al.  The treatment of atrophic, recalcitrant long-bone nonunion in the upper extremity with human recombinant bone morphogenetic protein-7 (rhBMP-7) and plate fixation: A retrospective review. , 2016, Injury.

[22]  G. Calori,et al.  Clinical effectiveness of Osigraft in long-bones non-unions. , 2015, Injury.

[23]  Y. Chai,et al.  Bone Morphogenetic Protein for the Healing of Tibial Fracture: A Meta-Analysis of Randomized Controlled Trials , 2015, PloS one.

[24]  J. Conway,et al.  BMP-7 versus BMP-2 for the treatment of long bone nonunion. , 2014, Orthopedics.

[25]  K. Egol,et al.  No advantage to rhBMP-2 in addition to autogenous graft for fracture nonunion. , 2014, Orthopedics.

[26]  Jie Song,et al.  pHEMA-nHA Encapsulation and Delivery of Vancomycin and rhBMP-2 Enhances its Role as a Bone Graft Substitute , 2013, Clinical orthopaedics and related research.

[27]  A. Simpson,et al.  The relative incidence of fracture non-union in the Scottish population (5.17 million): a 5-year epidemiological study , 2013, BMJ Open.

[28]  G. Canton,et al.  Clinical applications of growth factors in bone injuries: experience with BMPs. , 2013, Injury.

[29]  W. Obremskey,et al.  Bone morphogenetic protein-2 compared to autologous iliac crest bone graft in the treatment of long bone nonunion. , 2011, Orthopedics.

[30]  P. Giannoudis,et al.  Complications following autologous bone graft harvesting from the iliac crest and using the RIA: a systematic review. , 2011, Injury.

[31]  A. Stang Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses , 2010, European Journal of Epidemiology.

[32]  A. Wentzensen,et al.  Treatment of tibial shaft non-unions: bone morphogenetic proteins versus autologous bone graft. , 2009, Injury.

[33]  Yuuki Imai,et al.  Successful Spinal Fusion by E. coli-derived BMP-2-adsorbed Porous β-TCP Granules: A Pilot Study , 2009, Clinical orthopaedics and related research.

[34]  P. Giannoudis,et al.  Prevalence of long-bone non-unions. , 2007, Injury.

[35]  T. Miclau,et al.  Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions? , 2007, Injury.

[36]  D. Altman,et al.  Measuring inconsistency in meta-analyses , 2003, BMJ : British Medical Journal.

[37]  G. Zych,et al.  Osteogenic Protein-1 (Bone Morphogenetic Protein-7) in the Treatment of Tibial Nonunions: A Prospective, Randomized Clinical Trial Comparing rhOP-1 with Fresh Bone Autograft* , 2001, The Journal of bone and joint surgery. American volume.

[38]  S. Cook Preclinical and clinical evaluation of osteogenic protein-1 (BMP-7) in bony sites. , 1999, Orthopedics.

[39]  H. Chambers,et al.  Complications of iliac crest bone graft harvesting. , 1996, Clinical orthopaedics and related research.