The retino-geniculo-cortical pathway in Callithrix. II. The geniculo-cortical projection

SummaryAfter monocular injections of tritiated tracer precursors and transneuronal transport of tritiated compounds, a continuous band of radioactivity in layer IV of striate cortex of Callithrix jachus (Callithricidae, New World primates) indicated a complete desegregation of the crossed and uncrossed retino-cortical pathways. Comparison with the organization of these pathways in other primates suggests that a segregation of the retino-cortical pathways of opposite ocularities into alternating ocular dominance columns in striate cortex has developed independently in the different primate lines. The significance is discussed of the weak labeling of the region of area 17 representing the central retina as compared to the representation of the peripheral retina.

[1]  I. T. Diamond,et al.  Laminar organization of projections of the lateral geniculate nucleus to the striate cortex inGalago , 1976, Brain Research.

[2]  J. Tigges,et al.  Ocular dominance columns in the striate cortex of chimpanzee (Pan troglodytes) , 1979, Brain Research.

[3]  D. Hubel,et al.  Receptive fields and functional architecture of monkey striate cortex , 1968, The Journal of physiology.

[4]  B. Grafstein,et al.  Accumulation of radioactive protein in mouse cerebral cortex after injection of 3H-fucose into the eye. , 1973, Experimental neurology.

[5]  J. Kaas,et al.  The identification of relay neurons in the dorsal lateral geniculate nucleus of monkeys using horseradish peroxidase , 1978, The Journal of comparative neurology.

[6]  J. Tigges,et al.  Species difference between Old World and New World monkeys in the organization of the striate-prestriate association. , 1972, Brain research.

[7]  P. Rakić.  Prenatal development of the visual system in rhesus monkey. , 1977, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[8]  M. Ito,et al.  A study of binocular convergence in cat visual cortex neurons , 1977, Experimental Brain Research.

[9]  B. Grafstein.  Transneuronal Transfer of Radioactivity in the Central Nervous System , 1971, Science.

[10]  U. Dräger,et al.  Autoradiography of tritiated proline and fucose transported transneuronally from the eye to the visual cortex in pigmented and albino mice. , 1974, Brain research.

[11]  W. B. Spatz.  Topographically organized reciprocal connections between areas 17 and MT (visual area of superior temporal sulcus) in the marmoset Callithrix jacchus , 1977, Experimental Brain Research.

[12]  V. Casagrande,et al.  The projection of the primate superior colliculus upon the dorsal lateral geniculate nucleus: autoradiographic demonstration of interlaminar distribution of tectogeniculate axons , 1978, Brain Research.

[13]  T. Wiesel,et al.  Functional architecture of macaque monkey visual cortex , 1977 .

[14]  Columnar Organization of Area 17 in Normal and Monocularly Deprived Macaque Monkeys , 1976 .

[15]  T. Wiesel,et al.  The distribution of afferents representing the right and left eyes in the cat's visual cortex , 1977, Brain Research.

[16]  V. Casagrande,et al.  Transneuronal transport of tritiated fucose and proline in the visual pathways of tree shrew Tupaia glis , 1975, Brain Research.

[17]  D. Hubel,et al.  Plasticity of ocular dominance columns in monkey striate cortex. , 1977, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[18]  S. Levay,et al.  Ocular dominance columns and their development in layer IV of the cat's visual cortex: A quantitative study , 1978, The Journal of comparative neurology.

[19]  W. B. Spatz.  An efferent connection of the solitary cells of Meynert. A study with horseradish peroxidase in the marmoset Callithrix , 1975, Brain Research.

[20]  J. Lund.  Organization of neurons in the visual cortex, area 17, of the monkey (Macaca mulatta) , 1973, The Journal of comparative neurology.

[21]  David H. Hubel,et al.  An autoradiographic study of the retino-cortical projections in the tree shrew (Tupaia glis) , 1975, Brain Research.

[22]  J. Malpeli,et al.  The representation of the visual field in the lateral geniculate nucleus of Macaca mulatta , 1975, The Journal of comparative neurology.

[23]  A. Hendrickson,et al.  Pathways between striate cortex and subcortical regions in Macaca mulatta and Saimiri sciureus: Evidence for a reciprocal pulvinar connection , 1976, Experimental Neurology.

[24]  C. Gilbert,et al.  Laminar patterns of geniculocortical projection in the cat , 1976, Brain Research.

[25]  D H Hubel,et al.  Autoradiographic demonstration of ocular-dominance columns in the monkey striate cortex by means of transneuronal transport. , 1974, Brain research.

[26]  D. Hubel,et al.  Ferrier lecture - Functional architecture of macaque monkey visual cortex , 1977, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[27]  J. Tigges,et al.  Subcortical projections, cortical associations, and some intrinsic interlaminar connections of the striate cortex in the squirrel monkey (Saimiri) , 1970, The Journal of comparative neurology.

[28]  W. B. Spatz.  The retino-geniculo-cortical pathway in callithrix I. Intraspecific variations in the lamination pattern of the lateral geniculate nucleus , 1978, Experimental Brain Research.

[29]  J. Tigges,et al.  Complementary laminar terminations of afferents to area 17 originating in area 18 and in the lateral geniculate nucleus in squirrel monkey , 1977, The Journal of comparative neurology.

[30]  M. Karnovsky,et al.  THF EARLY STAGES OF ABSORPTION OF INJECTED HORSERADISH PEROXIDASE IN THE PROXIMAL TUBULES OF MOUSE KIDNEY: ULTRASTRUCTURAL CYTOCHEMISTRY BY A NEW TECHNIQUE , 1966, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[31]  D. Hubel,et al.  Laminar and columnar distribution of geniculo‐cortical fibers in the macaque monkey , 1972, The Journal of comparative neurology.

[32]  M. Ogren,et al.  The neurological organization of pathways between the dorsal lateral geniculate nucleus and visual cortex in old world and new world primates , 1978, The Journal of comparative neurology.

[33]  J. Kaas,et al.  The relay of ipsilateral and contralateral retinal input from the lateral geniculate nucleus to striate cortex in the owl monkey: a transneuronal transport study , 1976, Brain Research.

[34]  V. Casagrande,et al.  Transneuronal transport of [3H]proline within the visual system of the grey squirrel , 1977, Brain Research.

[35]  M. Reivich,et al.  Metabolic mapping of the primary visual system of the monkey by means of the autoradiographic [14C]deoxyglucose technique. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[36]  R. Laureno,et al.  Transport of radioactivity from eye to visual cortex in the mouse. , 1973, Experimental neurology.