Nanoparticles in photodynamic therapy.

Sasidharan Swarnalatha Lucky,†,§ Khee Chee Soo,‡ and Yong Zhang*,†,§,∥ †NUS Graduate School for Integrative Sciences & Engineering (NGS), National University of Singapore, Singapore, Singapore 117456 ‡Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore 169610 Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore, Singapore 117576 College of Chemistry and Life Sciences, Zhejiang Normal University, Zhejiang, P. R. China 321004

[1]  Zhuang Liu,et al.  Engineering of Multifunctional Nano‐Micelles for Combined Photothermal and Photodynamic Therapy Under the Guidance of Multimodal Imaging , 2014 .

[2]  Qingfeng Xiao,et al.  A smart upconversion-based mesoporous silica nanotheranostic system for synergetic chemo-/radio-/photodynamic therapy and simultaneous MR/UCL imaging. , 2014, Biomaterials.

[3]  Zhengquan Li,et al.  Photoactivation of core-shell titania coated upconversion nanoparticles and their effect on cell death. , 2014, Journal of materials chemistry. B.

[4]  Bin Liu,et al.  NIR photoregulated chemo- and photodynamic cancer therapy based on conjugated polyelectrolyte-drug conjugate encapsulated upconversion nanoparticles. , 2014, Nanoscale.

[5]  S. Shi,et al.  Cancer therapy improvement with mesoporous silica nanoparticles combining photodynamic and photothermal therapy. , 2014, Nanotechnology.

[6]  Meng Wang,et al.  Lanthanide-doped upconversion nanoparticles electrostatically coupled with photosensitizers for near-infrared-triggered photodynamic therapy. , 2014, Nanoscale.

[7]  Hana Cho,et al.  Biarmed poly(ethylene glycol)-(pheophorbide a)2 conjugate as a bioactivatable delivery carrier for photodynamic therapy. , 2014, Biomacromolecules.

[8]  Jin Chang,et al.  Lipid coated upconverting nanoparticles as NIR remote controlled transducer for simultaneous photodynamic therapy and cell imaging. , 2014, International journal of pharmaceutics.

[9]  Upconverting crystal/dextran-g-DOPE with high fluorescence stability for simultaneous photodynamic therapy and cell imaging. , 2014, Nanotechnology.

[10]  D. Shen,et al.  An upconversion nanoparticle--Zinc phthalocyanine based nanophotosensitizer for photodynamic therapy. , 2014, Biomaterials.

[11]  Won-Gun Koh,et al.  Fabrication of multifunctional layer-by-layer nanocapsules toward the design of theragnostic nanoplatform. , 2014, Biomacromolecules.

[12]  Xiu‐Ping Yan,et al.  A dual-targeting upconversion nanoplatform for two-color fluorescence imaging-guided photodynamic therapy. , 2014, Analytical chemistry.

[13]  Liang Cheng,et al.  Protein modified upconversion nanoparticles for imaging-guided combined photothermal and photodynamic therapy. , 2014, Biomaterials.

[14]  Zhen Cheng,et al.  NIR-light-induced surface-enhanced Raman scattering for detection and photothermal/photodynamic therapy of cancer cells using methylene blue-embedded gold nanorod@SiO2 nanocomposites. , 2014, Biomaterials.

[15]  Jin Chang,et al.  MC540 and upconverting nanocrystal coloaded polymeric liposome for near-infrared light-triggered photodynamic therapy and cell fluorescent imaging. , 2014, ACS applied materials & interfaces.

[16]  Yong Zhang,et al.  Encapsulation of Photosensitizers and Upconversion Nanocrystals in Lipid Micelles for Photodynamic Therapy , 2014 .

[17]  Yan Ma,et al.  Facile one-pot synthesis of hydrophilic NaYF4:Yb,Er@NaYF4:Yb active-core/active-shell nanoparticles with enhanced upconversion luminescence , 2014 .

[18]  R. Allison Photodynamic therapy: oncologic horizons. , 2014, Future oncology.

[19]  Weihong Tan,et al.  Targeted bioimaging and photodynamic therapy nanoplatform using an aptamer-guided G-quadruplex DNA carrier and near-infrared light. , 2013, Angewandte Chemie.

[20]  A. Tedesco,et al.  Antitumor activity of photodynamic therapy performed with nanospheres containing zinc-phthalocyanine , 2013, Journal of Nanobiotechnology.

[21]  Hai Zhu,et al.  Upconverting near-infrared light through energy management in core-shell-shell nanoparticles. , 2013, Angewandte Chemie.

[22]  Yong Wang,et al.  Effect of PEG-PDLLA polymeric nanovesicles loaded with doxorubicin and hematoporphyrin monomethyl ether on human hepatocellular carcinoma HepG2 cells in vitro , 2013, International journal of nanomedicine.

[23]  Zhuang Liu,et al.  PEG-functionalized iron oxide nanoclusters loaded with chlorin e6 for targeted, NIR light induced, photodynamic therapy. , 2013, Biomaterials.

[24]  Yuliang Zhao,et al.  A new near infrared photosensitizing nanoplatform containing blue-emitting up-conversion nanoparticles and hypocrellin A for photodynamic therapy of cancer cells. , 2013, Nanoscale.

[25]  Ruixia Chen,et al.  Near-IR-triggered photothermal/photodynamic dual-modality therapy system via chitosan hybrid nanospheres. , 2013, Biomaterials.

[26]  F. Rossetti,et al.  PLGA nanoparticles as delivery systems for protoporphyrin IX in topical PDT: cutaneous penetration of photosensitizer observed by fluorescence microscopy. , 2013, Journal of nanoscience and nanotechnology.

[27]  Stefan A. Elrington,et al.  A new nanoconstruct for epidermal growth factor receptor-targeted photo-immunotherapy of ovarian cancer. , 2013, Nanomedicine : nanotechnology, biology, and medicine.

[28]  Li Xu,et al.  Enhanced photodynamic efficiency of an aptamer-guided fullerene photosensitizer toward tumor cells. , 2013, Chemistry, an Asian journal.

[29]  Ya-ju Chang,et al.  Phospholipid-functionalized mesoporous silica nanocarriers for selective photodynamic therapy of cancer. , 2013, Biomaterials.

[30]  Hiroshi Iseki,et al.  Phase II clinical study on intraoperative photodynamic therapy with talaporfin sodium and semiconductor laser in patients with malignant brain tumors. , 2013, Journal of neurosurgery.

[31]  F. Guillemin,et al.  Photodynamic therapy with conventional and PEGylated liposomal formulations of mTHPC (temoporfin): comparison of treatment efficacy and distribution characteristics in vivo , 2013, International journal of nanomedicine.

[32]  U. Keyser,et al.  DNA origami nanopores: an emerging tool in biomedicine. , 2013, Nanomedicine.

[33]  Y. Jeong,et al.  Ursodeoxycholic acid-conjugated chitosan for photodynamic treatment of HuCC-T1 human cholangiocarcinoma cells. , 2013, International journal of pharmaceutics.

[34]  O. Taratula,et al.  A multifunctional theranostic platform based on phthalocyanine-loaded dendrimer for image-guided drug delivery and photodynamic therapy. , 2013, Molecular pharmaceutics.

[35]  Wei Fan,et al.  Engineering the Upconversion Nanoparticle Excitation Wavelength: Cascade Sensitization of Tri‐doped Upconversion Colloidal Nanoparticles at 800 nm , 2013 .

[36]  Kwangmeyung Kim,et al.  Cancer cell-specific photoactivity of pheophorbide a-glycol chitosan nanoparticles for photodynamic therapy in tumor-bearing mice. , 2013, Biomaterials.

[37]  Prakash Chandra,et al.  Enhanced upconversion luminescence in NaGdF4:Yb,Er nanocrystals by Fe3+ doping and their application in bioimaging. , 2013, Nanoscale.

[38]  N. Düzgüneş,et al.  Current status of liposomal porphyrinoid photosensitizers. , 2013, Drug discovery today.

[39]  A. Wu,et al.  Multifunctional photosensitizer-conjugated core–shell Fe3O4@NaYF4:Yb/Er nanocomplexes and their applications in T2-weighted magnetic resonance/upconversion luminescence imaging and photodynamic therapy of cancer cells , 2013 .

[40]  Wei Liu,et al.  A naphthalocyanine based near-infrared photosensitizer: synthesis and in vitro photodynamic activities. , 2013, Bioorganic & medicinal chemistry letters.

[41]  Ricardas Rotomskis,et al.  Two-photon excited quantum dots as energy donors for photosensitizer chlorin e6 , 2013, Journal of biomedical optics.

[42]  Michele T. Cooper,et al.  Adjuvant intraoperative photodynamic therapy in head and neck cancer. , 2013, JAMA otolaryngology-- head & neck surgery.

[43]  Zhuang Liu,et al.  Imaging‐Guided pH‐Sensitive Photodynamic Therapy Using Charge Reversible Upconversion Nanoparticles under Near‐Infrared Light , 2013 .

[44]  E. Reddi,et al.  Targeted delivery of photosensitizers: efficacy and selectivity issues revealed by multifunctional ORMOSIL nanovectors in cellular systems. , 2013, Nanoscale.

[45]  Zhe Wang,et al.  Single Continuous Wave Laser Induced Photodynamic/Plasmonic Photothermal Therapy Using Photosensitizer‐Functionalized Gold Nanostars , 2013, Advanced materials.

[46]  Liang Yan,et al.  Red-emitting upconverting nanoparticles for photodynamic therapy in cancer cells under near-infrared excitation. , 2013, Small.

[47]  C. Hopper,et al.  Photodynamic therapy in the management of lesions of the head and neck. , 2013, British Journal of Oral and Maxillofacial Surgery.

[48]  Anirban Sen Gupta,et al.  Photodynamic nanomedicine in the treatment of solid tumors: perspectives and challenges. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[49]  Xiaomin Liu,et al.  Facile synthesis of NaYF4:Yb, Ln/NaYF4:Yb core/shell upconversion nanoparticles via successive ion layer adsorption and one-pot reaction technique , 2013 .

[50]  M. Bureau,et al.  Magnetic and photoresponsive theranosomes: translating cell-released vesicles into smart nanovectors for cancer therapy. , 2013, ACS nano.

[51]  Elena Reddi,et al.  Folate-targeted PEGylated liposomes improve the selectivity of PDT with meta-tetra(hydroxyphenyl)-chlorin (m-THPC) , 2013, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[52]  Zhenzhong Zhang,et al.  Photodynamic therapy of a 2-methoxyestradiol tumor-targeting drug delivery system mediated by Asn-Gly-Arg in breast cancer , 2013, International journal of nanomedicine.

[53]  Hong Zhang,et al.  Separately doped upconversion-C60 nanoplatform for NIR imaging-guided photodynamic therapy of cancer cells. , 2013, Chemical communications.

[54]  Changfeng Wu,et al.  Enhanced deep-ultraviolet upconversion emission of Gd3+ sensitized by Yb3+ and Ho3+ in β-NaLuF4 microcrystals under 980 nm excitation , 2013 .

[55]  Harold S. Freeman,et al.  Dye Sensitizers for Photodynamic Therapy , 2013, Materials.

[56]  Guo Gao,et al.  Phase and Size Controllable Synthesis of NaYbF4 Nanocrystals in Oleic Acid/ Ionic Liquid Two-Phase System for Targeted Fluorescent Imaging of Gastric Cancer , 2013, Theranostics.

[57]  Y. Jeong,et al.  5-aminolevulinic acid-incorporated nanoparticles of methoxy poly(ethylene glycol)-chitosan copolymer for photodynamic therapy , 2013, International journal of nanomedicine.

[58]  P. Gunasekaran,et al.  Polyethylene glycol-modified gelatin/polylactic acid nanoparticles for enhanced photodynamic efficacy of a hypocrellin derivative in vitro. , 2013, Journal of biomedical nanotechnology.

[59]  C. Ehrhardt,et al.  Transferrin conjugation does not increase the efficiency of liposomal Foscan during in vitro photodynamic therapy of oesophageal cancer. , 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[60]  Samuel Achilefu,et al.  In vivo targeted deep-tissue photodynamic therapy based on near-infrared light triggered upconversion nanoconstruct. , 2013, ACS nano.

[61]  K. Moghissi,et al.  Photodynamic Therapy (PDT): PDT Mechanisms , 2013, Clinical endoscopy.

[62]  Ching-Wen Chen,et al.  Bioluminescence resonance energy transfer using luciferase-immobilized quantum dots for self-illuminated photodynamic therapy. , 2013, Biomaterials.

[63]  V. Uversky,et al.  Encyclopedia of Metalloproteins , 2013, Springer New York.

[64]  A. Stanimirović,et al.  Photodynamic therapy in dermatology: current treatments and implications. , 2012, Collegium antropologicum.

[65]  A. Suganthi,et al.  Synthesis and characterization of doxorubicin modified ZnO/PEG nanomaterials and its photodynamic action. , 2012, Journal of photochemistry and photobiology. B, Biology.

[66]  Muthu Kumara Gnanasammandhan,et al.  In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers , 2012, Nature Medicine.

[67]  M. Bryszewska,et al.  Dendrimers in photodynamic therapy. , 2012, Current medicinal chemistry.

[68]  O. Tillement,et al.  Multifunctional Peptide-Conjugated Hybrid Silica Nanoparticles for Photodynamic Therapy and MRI , 2012, Theranostics.

[69]  Eun Seong Lee,et al.  Multifunctional poly (lactide-co-glycolide) nanoparticles for luminescence/magnetic resonance imaging and photodynamic therapy. , 2012, International journal of pharmaceutics.

[70]  Christopher B. Murray,et al.  Metal-enhanced upconversion luminescence tunable through metal nanoparticle-nanophosphor separation. , 2012, ACS nano.

[71]  J. Fei,et al.  Hypocrellin-loaded gold nanocages with high two-photon efficiency for photothermal/photodynamic cancer therapy in vitro. , 2012, ACS nano.

[72]  Paras N. Prasad,et al.  (α-NaYbF4:Tm(3+))/CaF2 core/shell nanoparticles with efficient near-infrared to near-infrared upconversion for high-contrast deep tissue bioimaging. , 2012, ACS nano.

[73]  Jan C. Hummelen,et al.  Broadband dye-sensitized upconversion of near-infrared light , 2012, Nature Photonics.

[74]  Eun Seong Lee,et al.  Photodynamic therapy using glycol chitosan grafted fullerenes. , 2012, International journal of pharmaceutics.

[75]  Chunhua Yan,et al.  Triple-functional core-shell structured upconversion luminescent nanoparticles covalently grafted with photosensitizer for luminescent, magnetic resonance imaging and photodynamic therapy in vitro. , 2012, Nanoscale.

[76]  Yong-Eun Koo Lee,et al.  Multifunctional biodegradable polyacrylamide nanocarriers for cancer theranostics--a "see and treat" strategy. , 2012, ACS nano.

[77]  Tao Jiang,et al.  Upconversion emission enhancement of Gd3+ ions induced by surface plasmon field in Au@NaYF4 nanostructures codoped with Gd(3+)-Yb(3+)-Tm(3+) ions. , 2012, Journal of colloid and interface science.

[78]  Yang Liu,et al.  Anti‐cAngptl4 Ab‐Conjugated N‐TiO2/NaYF4:Yb,Tm Nanocomposite for Near Infrared‐Triggered Drug Release and Enhanced Targeted Cancer Cell Ablation , 2012, Advanced healthcare materials.

[79]  Nancy L Oleinick,et al.  EGFR-mediated intracellular delivery of Pc 4 nanoformulation for targeted photodynamic therapy of cancer: in vitro studies. , 2012, Nanomedicine : nanotechnology, biology, and medicine.

[80]  Qingfeng Xiao,et al.  A uniform sub-50 nm-sized magnetic/upconversion fluorescent bimodal imaging agent capable of generating singlet oxygen by using a 980 nm laser. , 2012, Chemistry.

[81]  Jiro Akimoto,et al.  Preliminary clinical report on safety and efficacy of photodynamic therapy using talaporfin sodium for malignant gliomas. , 2012, Photodiagnosis and photodynamic therapy.

[82]  Janko Kos,et al.  In vitro and in vivo characterization of temoporfin-loaded PEGylated PLGA nanoparticles for use in photodynamic therapy. , 2012, Nanomedicine.

[83]  D. Xing,et al.  Pyropheophorbide A and c(RGDyK) comodified chitosan-wrapped upconversion nanoparticle for targeted near-infrared photodynamic therapy. , 2012, Molecular pharmaceutics.

[84]  Jianhua Hao,et al.  Bi-functional NaLuF4:Gd3+/Yb3+/Tm3+ nanocrystals: structure controlled synthesis, near-infrared upconversion emission and tunable magnetic properties , 2012 .

[85]  Hong Zhang,et al.  Covalently assembled NIR nanoplatform for simultaneous fluorescence imaging and photodynamic therapy of cancer cells. , 2012, ACS nano.

[86]  Fang Wang,et al.  Multifunctional core-shell upconverting nanoparticles for imaging and photodynamic therapy of liver cancer cells. , 2012, Chemistry, an Asian journal.

[87]  Liang Yan,et al.  Mn2+ Dopant‐Controlled Synthesis of NaYF4:Yb/Er Upconversion Nanoparticles for in vivo Imaging and Drug Delivery , 2012, Advanced materials.

[88]  Zhiyu Qian,et al.  Amphiphilic chitosan modified upconversion nanoparticles for in vivo photodynamic therapy induced by near-infrared light , 2012 .

[89]  P. Gunasekaran,et al.  Gelatin nanocarrier enables efficient delivery and phototoxicity of hypocrellin B against a mice tumour model. , 2012, Journal of biomedical nanotechnology.

[90]  W. Cai,et al.  Enhanced upconversion emission in Yb3+ and Er3+ codoped NaGdF4 nanocrystals by introducing Li+ ions. , 2012, Nanoscale.

[91]  Haijun Yu,et al.  Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia. , 2011, Journal of controlled release : official journal of the Controlled Release Society.

[92]  Z. Dai,et al.  Conjugation of porphyrin to nanohybrid cerasomes for photodynamic diagnosis and therapy of cancer. , 2011, Angewandte Chemie.

[93]  Chun-Hua Yan,et al.  Bioimaging and toxicity assessments of near-infrared upconversion luminescent NaYF4:Yb,Tm nanocrystals. , 2011, Biomaterials.

[94]  Shao Q Yao,et al.  Photosensitizer-doped conjugated polymer nanoparticles for simultaneous two-photon imaging and two-photon photodynamic therapy in living cells. , 2011, Nanoscale.

[95]  Michael R Hamblin,et al.  Photodynamic therapy with fullerenes in vivo: reality or a dream? , 2011, Nanomedicine.

[96]  M. Maynadier,et al.  Mannose-functionalized mesoporous silica nanoparticles for efficient two-photon photodynamic therapy of solid tumors. , 2011, Angewandte Chemie.

[97]  Lianzhou Wang,et al.  Positive and Negative Lattice Shielding Effects Co‐existing in Gd (III) Ion Doped Bifunctional Upconversion Nanoprobes , 2011 .

[98]  Kai Yang,et al.  In vivo pharmacokinetics, long-term biodistribution and toxicology study of functionalized upconversion nanoparticles in mice. , 2011, Nanomedicine.

[99]  Wei Feng,et al.  Sub-10 nm hexagonal lanthanide-doped NaLuF4 upconversion nanocrystals for sensitive bioimaging in vivo. , 2011, Journal of the American Chemical Society.

[100]  K. Moghissi,et al.  Photodynamic therapy (PDT) for lung cancer. , 2011, Photodiagnosis and photodynamic therapy.

[101]  Zhuang Liu,et al.  Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles. , 2011, Biomaterials.

[102]  G. Zheng,et al.  Liposomal nanostructures for photosensitizer delivery , 2011, Lasers in surgery and medicine.

[103]  Christoph Peters,et al.  Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment. , 2011, Nature nanotechnology.

[104]  Vitaly Khanadeev,et al.  Nanocomposites containing silica-coated gold-silver nanocages and Yb-2,4-dimethoxyhematoporphyrin: multifunctional capability of IR-luminescence detection, photosensitization, and photothermolysis. , 2011, ACS nano.

[105]  S. Andersson-Engels,et al.  An overview on preclinical and clinical experiences with photodynamic therapy for bladder cancer. , 2011, The Canadian journal of urology.

[106]  Yibin Kang,et al.  Pegylated Composite Nanoparticles Containing Upconverting Phosphors and meso‐Tetraphenyl porphine (TPP) for Photodynamic Therapy , 2011 .

[107]  Xiaosong Wang,et al.  Cytotoxicity and photocytotoxicity of structure-defined water-soluble C60/micelle supramolecular nanoparticles , 2011, Nanotechnology.

[108]  Ick Chan Kwon,et al.  Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/off system. , 2011, Biomaterials.

[109]  Michael R Hamblin,et al.  Cell Death Pathways in Photodynamic Therapy of Cancer , 2011, Cancers.

[110]  Dan Wang,et al.  Using 915 nm laser excited Tm³+/Er³+/Ho³+- doped NaYbF4 upconversion nanoparticles for in vitro and deeper in vivo bioimaging without overheating irradiation. , 2011, ACS nano.

[111]  Jing Lin,et al.  Photosensitizer-conjugated magnetic nanoparticles for in vivo simultaneous magnetofluorescent imaging and targeting therapy. , 2011, Biomaterials.

[112]  D. Russell,et al.  Targeted photodynamic therapy of breast cancer cells using antibody-phthalocyanine-gold nanoparticle conjugates , 2011, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[113]  N. Miwa,et al.  Anticancer effects of fullerene [C60] included in polyethylene glycol combined with visible light irradiation through ROS generation and DNA fragmentation on fibrosarcoma cells with scarce cytotoxicity to normal fibroblasts. , 2011, Oncology research.

[114]  Pei-Nan Wang,et al.  Study on the visible-light-induced photokilling effect of nitrogen-doped TiO2 nanoparticles on cancer cells , 2011, Nanoscale research letters.

[115]  So Jin Lee,et al.  Photosensitizer-Conjugated Human Serum Albumin Nanoparticles for Effective Photodynamic Therapy , 2011, Theranostics.

[116]  Chulhong Kim,et al.  Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents. , 2011, Nature materials.

[117]  J. Reynolds,et al.  Nanodrug applications in photodynamic therapy. , 2011, Photodiagnosis and photodynamic therapy.

[118]  Kok Wai Cheah,et al.  Biocompatible CdSe quantum dot-based photosensitizer under two-photon excitation for photodynamic therapy , 2011 .

[119]  Jing Chen,et al.  Controllable synthesis of NaYF(4) : Yb,Er upconversion nanophosphors and their application to in vivo imaging of Caenorhabditis elegans. , 2011, Journal of materials chemistry.

[120]  Malcolm E. Kenney,et al.  Deep penetration of a PDT drug into tumors by noncovalent drug-gold nanoparticle conjugates. , 2011, Journal of the American Chemical Society.

[121]  Shao Q Yao,et al.  Enhanced two-photon singlet oxygen generation by photosensitizer-doped conjugated polymer nanoparticles. , 2011, Langmuir : the ACS journal of surfaces and colloids.

[122]  Yongdoo Choi,et al.  Gold nanorod-photosensitizer complex for near-infrared fluorescence imaging and photodynamic/photothermal therapy in vivo. , 2011, ACS nano.

[123]  S. Hackenberg,et al.  Zinc oxide nanoparticles induce photocatalytic cell death in human head and neck squamous cell carcinoma cell lines in vitro. , 2010, International journal of oncology.

[124]  Tayyaba Hasan,et al.  Ki-67 as a molecular target for therapy in an in vitro three-dimensional model for ovarian cancer. , 2010, Cancer research.

[125]  Robert Blumenthal,et al.  Light-sensitive lipid-based nanoparticles for drug delivery: design principles and future considerations for biological applications , 2010, Molecular membrane biology.

[126]  Yang Yang,et al.  Long-term in vivo biodistribution imaging and toxicity of polyacrylic acid-coated upconversion nanophosphors. , 2010, Biomaterials.

[127]  H. S. de Bruijn,et al.  Fractionated Illumination at Low Fluence Rate Photodynamic Therapy in Mice , 2010, Photochemistry and photobiology.

[128]  U. Schubert,et al.  Poly(ethylene glycol) in drug delivery: pros and cons as well as potential alternatives. , 2010, Angewandte Chemie.

[129]  P. Venieratos,et al.  Photo-induced treatment of breast epithelial cancer cells using nanostructured titanium dioxide solution , 2010 .

[130]  John-Christopher Boyer,et al.  Absolute quantum yield measurements of colloidal NaYF4: Er3+, Yb3+ upconverting nanoparticles. , 2010, Nanoscale.

[131]  M. Thanou,et al.  Targeting nanoparticles to cancer. , 2010, Pharmacological research.

[132]  Laurence Raehm,et al.  Silica-based nanoparticles for photodynamic therapy applications. , 2010, Nanoscale.

[133]  D. A. Russell,et al.  The in vivo efficacy of phthalocyanine-nanoparticle conjugates for the photodynamic therapy of amelanotic melanoma. , 2010, European journal of cancer.

[134]  Matthias Wacker,et al.  Photosensitizer loaded HSA nanoparticles. I: Preparation and photophysical properties. , 2010, International journal of pharmaceutics.

[135]  V. Bagnato,et al.  Future of oncologic photodynamic therapy. , 2010, Future oncology.

[136]  Yong Zhang,et al.  Singlet oxygen-induced apoptosis of cancer cells using upconversion fluorescent nanoparticles as a carrier of photosensitizer. , 2010, Nanomedicine : nanotechnology, biology, and medicine.

[137]  Ming-Jium Shieh,et al.  Development of pH sensitive 2-(diisopropylamino)ethyl methacrylate based nanoparticles for photodynamic therapy , 2010, Nanotechnology.

[138]  Hui Jiang,et al.  The Photodynamic Effect of Different Size ZnO Nanoparticles on Cancer Cell Proliferation In Vitro , 2010, Nanoscale research letters.

[139]  N. V. Kudinova,et al.  Photodynamic therapy of cancer: Search for ideal photosensitizer , 2010 .

[140]  C. S. Lim,et al.  Simultaneous phase and size control of upconversion nanocrystals through lanthanide doping , 2010, Nature.

[141]  Jun Li,et al.  Delivery and efficacy of a cancer drug as a function of the bond to the gold nanoparticle surface. , 2010, Langmuir : the ACS journal of surfaces and colloids.

[142]  Tayyaba Hasan,et al.  Theranostic nanocells for simultaneous imaging and photodynamic therapy of pancreatic cancer , 2010, BiOS.

[143]  L. Lévy,et al.  Pp IX Silica Nanoparticles Demonstrate Differential Interactions with In Vitro Tumor Cell Lines and In Vivo Mouse Models of Human Cancers , 2010, Photochemistry and photobiology.

[144]  A. Wu,et al.  Induction of cytotoxicity by photoexcitation of TiO2 can prolong survival in glioma-bearing mice , 2010, Molecular Biology Reports.

[145]  Doaa A. Abdel Fadeel,et al.  Zinc phthalocyanine-loaded PLGA biodegradable nanoparticles for photodynamic therapy in tumor-bearing mice , 2010, Lasers in Medical Science.

[146]  Yu-Ying He,et al.  Enhanced photodynamic efficacy towards melanoma cells by encapsulation of Pc4 in silica nanoparticles. , 2009, Toxicology and applied pharmacology.

[147]  Taeghwan Hyeon,et al.  Nonblinking and Nonbleaching Upconverting Nanoparticles as an Optical Imaging Nanoprobe and T1 Magnetic Resonance Imaging Contrast Agent , 2009 .

[148]  Hui Guo,et al.  Mesoporous-silica-coated up-conversion fluorescent nanoparticles for photodynamic therapy. , 2009, Small.

[149]  M. Haase,et al.  Synthesis of Hexagonal Yb3+,Er3+‐Doped NaYF4 Nanocrystals at Low Temperature , 2009 .

[150]  Fuyou Li,et al.  High contrast upconversion luminescence targeted imaging in vivo using peptide-labeled nanophosphors. , 2009, Analytical chemistry.

[151]  Zhi-Gang Chen,et al.  Synthesis, characterization, and in vivo targeted imaging of amine-functionalized rare-earth up-converting nanophosphors. , 2009, Biomaterials.

[152]  G. Miotto,et al.  The cellular uptake of meta-tetra(hydroxyphenyl)chlorin entrapped in organically modified silica nanoparticles is mediated by serum proteins , 2009, Nanotechnology.

[153]  Chin‐Hung Lai,et al.  A New Series of Quadrupolar Type Two‐Photon Absorption Chromophores Bearing 11, 12‐Dibutoxydibenzo[a,c]‐phenazine Bridged Amines; Their Applications in Two‐Photon Fluorescence Imaging and Two‐Photon Photodynamic Therapy , 2009 .

[154]  Chun Jiang,et al.  Theoretical Model of Yb $^{3 + }$ -Er $^{3 + }$ -Tm $^{3 + }$ -Codoped System for White Light Generation , 2009 .

[155]  Barry Lai,et al.  A high-performance nanobio photocatalyst for targeted brain cancer therapy. , 2009, Nano letters.

[156]  Bo Tang,et al.  Multifunctional core-shell nanoparticles as highly efficient imaging and photosensitizing agents. , 2009, Langmuir : the ACS journal of surfaces and colloids.

[157]  Chenghui Liu,et al.  Monodisperse, size-tunable and highly efficient β-NaYF4:Yb,Er(Tm) up-conversion luminescent nanospheres: controllable synthesis and their surface modifications , 2009 .

[158]  Peter H Lin,et al.  Current advances in research and clinical applications of PLGA-based nanotechnology , 2009, Expert review of molecular diagnostics.

[159]  Ick Chan Kwon,et al.  Tumor specificity and therapeutic efficacy of photosensitizer-encapsulated glycol chitosan-based nanoparticles in tumor-bearing mice. , 2009, Biomaterials.

[160]  P. Dobbin,et al.  Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy. , 2009, Journal of controlled release : official journal of the Controlled Release Society.

[161]  Hong Zhang,et al.  Upconversion luminescence of β-NaYF4: Yb3+, Er3+@β-NaYF4 core/shell nanoparticles: Excitation power density and surface dependence , 2009 .

[162]  Xingping Zhou,et al.  Magnetic chitosan nanoparticles as a drug delivery system for targeting photodynamic therapy , 2009, Nanotechnology.

[163]  K. Soo,et al.  The effect of photodynamic therapy on tumor angiogenesis , 2009, Cellular and Molecular Life Sciences.

[164]  Xiaogang Liu,et al.  Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals. , 2009, Chemical Society reviews.

[165]  Marcel Garcia,et al.  Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy. , 2009, Chemical communications.

[166]  M. O. Baratti,et al.  In vitro photodynamic activity of chloro(5,10,15,20-tetraphenylporphyrinato)indium(III) loaded-poly(lactide-co-glycolide) nanoparticles in LNCaP prostate tumour cells. , 2009, Journal of photochemistry and photobiology. B, Biology.

[167]  Xingping Zhou,et al.  Studies on Preparation of Photosensitizer Loaded Magnetic Silica Nanoparticles and Their Anti-Tumor Effects for Targeting Photodynamic Therapy , 2009, Nanoscale research letters.

[168]  Robert Austin,et al.  Nanofabricated upconversion nanoparticles for photodynamic therapy. , 2009, Optics express.

[169]  Sailing He,et al.  Colloidal mesoporous silica nanoparticles with protoporphyrin IX encapsulated for photodynamic therapy. , 2009, Journal of biomedical optics.

[170]  N. Oku,et al.  Antiangiogenic photodynamic therapy with targeted liposomes. , 2009, Methods in enzymology.

[171]  Felix Kratz,et al.  Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[172]  Yong Zhang,et al.  Nanoparticles in photodynamic therapy: an emerging paradigm. , 2008, Advanced drug delivery reviews.

[173]  Wei Chen,et al.  Nanoparticle Self-Lighting Photodynamic Therapy For Cancer Treatment , 2008 .

[174]  N. Oku,et al.  Phototoxicity of coproporphyrin as a novel photodynamic therapy was enhanced by liposomalization. , 2008, Toxicology letters.

[175]  W. Soboyejo,et al.  Biofunctionalization, cytotoxicity, and cell uptake of lanthanide doped hydrophobically ligated NaYF4 upconversion nanophosphors , 2008 .

[176]  Wenfang Sun,et al.  Synthesis and photophysics of benzotexaphyrin: a near-infrared emitter and photosensitizer. , 2008, Journal of the American Chemical Society.

[177]  K. Sheng,et al.  Semiconductor nanoparticles as energy mediators for photosensitizer-enhanced radiotherapy. , 2008, International journal of radiation oncology, biology, physics.

[178]  François Guillemin,et al.  Nanoparticles as vehicles for delivery of photodynamic therapy agents. , 2008, Trends in biotechnology.

[179]  Yong Zhang,et al.  Biocompatibility of silica coated NaYF(4) upconversion fluorescent nanocrystals. , 2008, Biomaterials.

[180]  A. Persin,et al.  Fractionated illumination improves the outcome in the treatment of precancerous lesions with photodynamic therapy. , 2008, Collegium antropologicum.

[181]  Ross W. Boyle,et al.  Photodynamic Therapy and the Development of Metal-Based Photosensitisers , 2008, Metal-based drugs.

[182]  Serge Mordon,et al.  Comparison of continuous and fractionated illumination during hexaminolaevulinate-photodynamic therapy. , 2008, Photodiagnosis and photodynamic therapy.

[183]  Mark E. Davis,et al.  Nanoparticle therapeutics: an emerging treatment modality for cancer , 2008, Nature Reviews Drug Discovery.

[184]  Zhengquan Li,et al.  An efficient and user-friendly method for the synthesis of hexagonal-phase NaYF4:Yb, Er/Tm nanocrystals with controllable shape and upconversion fluorescence , 2008, Nanotechnology.

[185]  Zheng Huang,et al.  Photodynamic Therapy for Treatment of Solid Tumors — Potential and Technical Challenges , 2008, Technology in cancer research & treatment.

[186]  Jarod C Finlay,et al.  The role of photodynamic therapy (PDT) physics. , 2008, Medical physics.

[187]  Malini Olivo,et al.  Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy , 2008, Molecular Cancer.

[188]  M. Grinstaff,et al.  Therapeutic and diagnostic applications of dendrimers for cancer treatment. , 2008, Advanced drug delivery reviews.

[189]  Xiaogang Liu,et al.  Upconversion multicolor fine-tuning: visible to near-infrared emission from lanthanide-doped NaYF4 nanoparticles. , 2008, Journal of the American Chemical Society.

[190]  E. Kang,et al.  Self-assembled glycol chitosan nanoparticles for the sustained and prolonged delivery of antiangiogenic small peptide drugs in cancer therapy. , 2008, Biomaterials.

[191]  K. Ogawa,et al.  Recent advances in two-photon photodynamic therapy. , 2008, Anti-cancer agents in medicinal chemistry.

[192]  T. Takeya,et al.  Solubilisation of [60]fullerenes using block copolymers and evaluation of their photodynamic activities. , 2008, Organic & biomolecular chemistry.

[193]  William C. Zamboni,et al.  Concept and clinical evaluation of carrier-mediated anticancer agents. , 2008, The oncologist.

[194]  K. Moghissi,et al.  Update on the current indications, practice and results of photodynamic therapy (PDT) in early central lung cancer (ECLC). , 2008, Photodiagnosis and photodynamic therapy.

[195]  Mauro Ferrari,et al.  Nanogeometry: beyond drug delivery. , 2008, Nature nanotechnology.

[196]  C H Sibata,et al.  Bio-nanotechnology and photodynamic therapy--state of the art review. , 2008, Photodiagnosis and photodynamic therapy.

[197]  Fuyou Li,et al.  Versatile synthesis strategy for carboxylic acid-functionalized upconverting nanophosphors as biological labels. , 2008, Journal of the American Chemical Society.

[198]  Smita Dayal,et al.  Semiconductor quantum dots as two-photon sensitizers. , 2008, Journal of the American Chemical Society.

[199]  K K Jain,et al.  Recent Advances in Nanooncology , 2008, Technology in cancer research & treatment.

[200]  Saber M Hussain,et al.  Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique. , 2008, Toxicological sciences : an official journal of the Society of Toxicology.

[201]  Zhang Yong,et al.  Upconverting nanoparticles as nanotransducers for photodynamic therapy in cancer cells. , 2008, Nanomedicine.

[202]  Patrizia Agostinis,et al.  Molecular effectors of multiple cell death pathways initiated by photodynamic therapy. , 2007, Biochimica et biophysica acta.

[203]  Indrajit Roy,et al.  Organically modified silica nanoparticles with covalently incorporated photosensitizer for photodynamic therapy of cancer. , 2007, Nano letters.

[204]  M. Barberi-Heyob,et al.  Phthalocyanines covalently bound to biomolecules for a targeted photodynamic therapy. , 2007, Current medicinal chemistry.

[205]  Shimon Weiss,et al.  Singlet oxygen production by Peptide-coated quantum dot-photosensitizer conjugates. , 2007, Journal of the American Chemical Society.

[206]  T. Takeya,et al.  Induction of cell death by photodynamic therapy with water-soluble lipid-membrane-incorporated [60]fullerene. , 2007, Organic & biomolecular chemistry.

[207]  R. Boyle,et al.  Development and characterization of novel photosensitizer :  scFv conjugates for use in photodynamic therapy of cancer , 2007, Immunology.

[208]  Manoj Kumar,et al.  Versatile photosensitizers for photodynamic therapy at infrared excitation. , 2007, Journal of the American Chemical Society.

[209]  M. Amiji,et al.  Poly(ethylene glycol)-modified thiolated gelatin nanoparticles for glutathione-responsive intracellular DNA delivery. , 2007, Nanomedicine : nanotechnology, biology, and medicine.

[210]  P. Dobbin,et al.  Macromolecular delivery of 5-aminolaevulinic acid for photodynamic therapy using dendrimer conjugates , 2007, Molecular Cancer Therapeutics.

[211]  Paras N Prasad,et al.  Organically modified silica nanoparticles co-encapsulating photosensitizing drug and aggregation-enhanced two-photon absorbing fluorescent dye aggregates for two-photon photodynamic therapy. , 2007, Journal of the American Chemical Society.

[212]  Gan-Moog Chow,et al.  Water -soluble NaYF4:Yb,Er (Tm)/NaYF4/Polymer Core/Shell/Shell nanoparticles with significant enhancement of upconversion fluorescence , 2007 .

[213]  Kyung-Ja Cho,et al.  In vivo tumor targeting and radionuclide imaging with self-assembled nanoparticles: mechanisms, key factors, and their implications. , 2007, Biomaterials.

[214]  N. Nitta,et al.  Preparation of PEG-conjugated fullerene containing Gd3+ ions for photodynamic therapy. , 2007, Journal of controlled release : official journal of the Controlled Release Society.

[215]  L. Lilge,et al.  Implicit and explicit dosimetry in photodynamic therapy: a New paradigm , 1997, Lasers in Medical Science.

[216]  Ann-Marie Wennberg,et al.  Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005. , 2007, Journal of the American Academy of Dermatology.

[217]  Feng Wang,et al.  Multicolour PEI/NaGdF4:Ce3+,Ln3+ nanocrystals by single-wavelength excitation , 2007 .

[218]  R. Gurny,et al.  Hypericin-loaded nanoparticles for the photodynamic treatment of ovarian cancer. , 2006, International journal of pharmaceutics.

[219]  Zhengquan Li,et al.  Monodisperse silica-coated polyvinylpyrrolidone/NaYF(4) nanocrystals with multicolor upconversion fluorescence emission. , 2006, Angewandte Chemie.

[220]  Raoul Kopelman,et al.  Vascular Targeted Nanoparticles for Imaging and Treatment of Brain Tumors , 2006, Clinical Cancer Research.

[221]  Feng Wang,et al.  Synthesis of polyethylenimine/NaYF4 nanoparticles with upconversion fluorescence , 2006 .

[222]  Raoul Kopelman,et al.  Nanoparticles for two-photon photodynamic therapy in living cells. , 2006, Nano letters.

[223]  Michael S Patterson,et al.  Singlet Oxygen Luminescence Dosimetry (SOLD) for Photodynamic Therapy: Current Status, Challenges and Future Prospects , 2006, Photochemistry and photobiology.

[224]  Christopher G Thanos,et al.  The pinpoint promise of nanoparticle-based drug delivery and molecular diagnosis. , 2006, Biomolecular engineering.

[225]  Y. Nosaka,et al.  Direct detection of OH radicals diffused to the gas phase from the UV-irradiated photocatalytic TiO2 surfaces by means of laser-induced fluorescence spectroscopy. , 2006, The journal of physical chemistry. B.

[226]  David A Russell,et al.  Intracellular photodynamic therapy with photosensitizer-nanoparticle conjugates: cancer therapy using a ‘Trojan horse’ , 2006, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[227]  J. M. Marchetti,et al.  Indocyanine green nanoparticles useful for photomedicine. , 2006, Photomedicine and laser surgery.

[228]  R. Boyle,et al.  Synthesis and in vitro investigation of cationic 5,15-diphenyl porphyrin-monoclonal antibody conjugates as targeted photodynamic sensitisers. , 2006, International journal of oncology.

[229]  W. Gradishar,et al.  Albumin-bound paclitaxel: a next-generation taxane , 2006, Expert opinion on pharmacotherapy.

[230]  Fiorenzo Vetrone,et al.  Synthesis of colloidal upconverting NaYF4 nanocrystals doped with Er3+, Yb3+ and Tm3+, Yb3+ via thermal decomposition of lanthanide trifluoroacetate precursors. , 2006, Journal of the American Chemical Society.

[231]  Matthias Selke,et al.  Singlet oxygen generation from water-soluble quantum dot-organic dye nanocomposites. , 2006, Journal of the American Chemical Society.

[232]  Wei Chen,et al.  Using nanoparticles to enable simultaneous radiation and photodynamic therapies for cancer treatment. , 2006, Journal of nanoscience and nanotechnology.

[233]  Scott C. Brown,et al.  Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.

[234]  Ick Chan Kwon,et al.  Hydrophobically modified glycol chitosan nanoparticles as carriers for paclitaxel. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[235]  Judith Grimm,et al.  Upconversion spectroscopy and properties of NaYF4 doped with Er3+, Tm3+ and/or Yb3+ , 2006 .

[236]  Vishal Saxena,et al.  Polymeric nanoparticulate delivery system for Indocyanine green: biodistribution in healthy mice. , 2006, International journal of pharmaceutics.

[237]  P. Dobbin,et al.  Enhanced porphyrin accumulation using dendritic derivatives of 5-aminolaevulinic acid for photodynamic therapy: an in vitro study. , 2006, The international journal of biochemistry & cell biology.

[238]  B. Pogue,et al.  Vascular and cellular targeting for photodynamic therapy. , 2006, Critical reviews in eukaryotic gene expression.

[239]  P. Dobbin,et al.  Investigation of a novel dendritic derivative of 5-aminolaevulinic acid for photodynamic therapy. , 2006, The international journal of biochemistry & cell biology.

[240]  Donald A Tomalia,et al.  Dendrimers in biomedical applications--reflections on the field. , 2005, Advanced drug delivery reviews.

[241]  D. Nowis,et al.  The influence of photodynamic therapy on the immune response. , 2005, Photodiagnosis and photodynamic therapy.

[242]  R. Weissleder,et al.  Polymeric nanoparticle preparation that eradicates tumors. , 2005, Nano letters.

[243]  J. Bünzli,et al.  Taking advantage of luminescent lanthanide ions. , 2005, Chemical Society reviews.

[244]  K. Avgoustakis,et al.  Biodistribution properties of nanoparticles based on mixtures of PLGA with PLGA-PEG diblock copolymers. , 2005, International journal of pharmaceutics.

[245]  M. Olivo,et al.  Enhancing the therapeutic responsiveness of photodynamic therapy with the antiangiogenic agents SU5416 and SU6668 in murine nasopharyngeal carcinoma models , 2005, Cancer Chemotherapy and Pharmacology.

[246]  Michael R Hamblin,et al.  Mechanisms in photodynamic therapy: Part three-Photosensitizer pharmacokinetics, biodistribution, tumor localization and modes of tumor destruction. , 2005, Photodiagnosis and photodynamic therapy.

[247]  Raoul Kopelman,et al.  Multifunctional nanoparticle platforms for in vivo MRI enhancement and photodynamic therapy of a rat brain cancer , 2005 .

[248]  Oliver J. Clarke,et al.  The development and characterisation of porphyrin isothiocyanate–monoclonal antibody conjugates for photoimmunotherapy , 2005, British Journal of Cancer.

[249]  R. Gurny,et al.  In vitro and in vivo activities of verteporfin-loaded nanoparticles. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[250]  K. Krämer,et al.  Novel materials doped with trivalent lanthanides and transition metal ions showing near-infrared to visible photon upconversion , 2005 .

[251]  Wei Tang,et al.  Photodynamic Characterization and In Vitro Application of Methylene Blue-containing Nanoparticle Platforms¶ , 2005, Photochemistry and photobiology.

[252]  D. McDonald,et al.  Cellular abnormalities of blood vessels as targets in cancer. , 2005, Current opinion in genetics & development.

[253]  V. Torchilin Recent advances with liposomes as pharmaceutical carriers , 2005, Nature Reviews Drug Discovery.

[254]  J. Pouysségur,et al.  The hypoxia-inducible factor and tumor progression along the angiogenic pathway. , 2005, International review of cytology.

[255]  P. Heegaard,et al.  Dendrimers in drug research. , 2004, Chemical Society reviews.

[256]  M. Haase,et al.  Highly Efficient Multicolour Upconversion Emission in Transparent Colloids of Lanthanide‐Doped NaYF4 Nanocrystals , 2004 .

[257]  Michael R Hamblin,et al.  Mechanisms in photodynamic therapy: part one-photosensitizers, photochemistry and cellular localization. , 2004, Photodiagnosis and photodynamic therapy.

[258]  Jörg Huwyler,et al.  Transferrin-conjugated liposome targeting of photosensitizer AlPcS4 to rat bladder carcinoma cells. , 2004, Journal of the National Cancer Institute.

[259]  Ai-Ping Zhang,et al.  Photocatalytic killing effect of TiO2 nanoparticles on Ls-174-t human colon carcinoma cells. , 2004, World journal of gastroenterology.

[260]  Wenjun Yang,et al.  Synthesis, Characterization, and Biological Application of Size-Controlled Nanocrystalline NaYF4:Yb,Er Infrared-to-Visible Up-Conversion Phosphors , 2004 .

[261]  Christoph Abels,et al.  Targeting of the vascular system of solid tumours by photodynamic therapy (PDT) , 2004, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[262]  William M. Yen,et al.  Inorganic Phosphors: Compositions, Preparation and Optical Properties , 2004 .

[263]  Timothy Zhu,et al.  Phase II trial of pleural photodynamic therapy and surgery for patients with non-small-cell lung cancer with pleural spread. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[264]  C. Sibata,et al.  Photosensitizers in clinical PDT. , 2004, Photodiagnosis and photodynamic therapy.

[265]  Sérgio Simões,et al.  On the formulation of pH-sensitive liposomes with long circulation times. , 2004, Advanced drug delivery reviews.

[266]  T. Tatsuma,et al.  Detection of H2O2 released from TiO2 photocatalyst to air. , 2004, Analytical sciences : the international journal of the Japan Society for Analytical Chemistry.

[267]  Markus P. Hehlen,et al.  Hexagonal Sodium Yttrium Fluoride Based Green and Blue Emitting Upconversion Phosphors , 2004 .

[268]  N. Oku,et al.  PEGylation of liposome decreases the susceptibility of liposomal drug in cancer photodynamic therapy. , 2004, Biological & pharmaceutical bulletin.

[269]  Ruomei Gao,et al.  Nanomaterials and singlet oxygen photosensitizers: potential applications in photodynamic therapy , 2004 .

[270]  P. D. de Witte,et al.  Liposomes for photodynamic therapy. , 2004, Advanced drug delivery reviews.

[271]  N. Nishioka,et al.  Cost-Effectiveness of Photodynamic Therapy for Treatment of Barrett's Esophagus with High Grade Dysplasia , 2003, Digestive Diseases and Sciences.

[272]  V. Lenaerts,et al.  Biodegradable Nanospheres Containing Phthalocyanines and Naphthalocyanines for Targeted Photodynamic Tumor Therapy , 1991, Pharmaceutical Research.

[273]  Paras N. Prasad,et al.  Polymer science and technology for new generation photonics and biophotonics , 2004 .

[274]  F. Auzel Upconversion and anti-Stokes processes with f and d ions in solids. , 2004, Chemical reviews.

[275]  T. Aida,et al.  Polyion complex micelles entrapping cationic dendrimer porphyrin: effective photosensitizer for photodynamic therapy of cancer. , 2003, Journal of controlled release : official journal of the Controlled Release Society.

[276]  Xiaobo Chen,et al.  Semiconductor quantum dots for photodynamic therapy. , 2003, Journal of the American Chemical Society.

[277]  F. Hetzel,et al.  Hyperoxygenation Enhances the Tumor Cell Killing of Photofrin-mediated Photodynamic Therapy¶ , 2003, Photochemistry and photobiology.

[278]  J. Frangioni In vivo near-infrared fluorescence imaging. , 2003, Current opinion in chemical biology.

[279]  P. Prasad,et al.  Effect of crystal nature on upconversion luminescence in Er3+:ZrO2 nanocrystals , 2003 .

[280]  K. Avgoustakis,et al.  Effect of copolymer composition on the physicochemical characteristics, in vitro stability, and biodistribution of PLGA-mPEG nanoparticles. , 2003, International journal of pharmaceutics.

[281]  Indrajit Roy,et al.  Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: a novel drug-carrier system for photodynamic therapy. , 2003, Journal of the American Chemical Society.

[282]  R. Gurny,et al.  Encapsulation of p-THPP into Nanoparticles: Cellular Uptake, Subcellular Localization and Effect of Serum on Photodynamic Activity¶ , 2003 .

[283]  R. Jain,et al.  Photodynamic therapy for cancer , 2003, Nature Reviews Cancer.

[284]  Mansoor Amiji,et al.  Chitosan-based gastrointestinal delivery systems. , 2003, Journal of controlled release : official journal of the Controlled Release Society.

[285]  N. Kuznetsova,et al.  Sulfonated phthalocyanines: aggregation and singlet oxygen quantum yield in aqueous solutions , 2003 .

[286]  Robert Gurny,et al.  Enhanced photodynamic activity of meso-tetra(4-hydroxyphenyl)porphyrin by incorporation into sub-200 nm nanoparticles. , 2003, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[287]  T. Aida,et al.  pH-sensitive Assembly of Light-Harvesting Dendrimer Zinc Porphyrin Bearing Peripheral Groups of Primary Amine with Poly(ethylene glycol)-b-poly(aspartic acid) in Aqueous Solution , 2003 .

[288]  P. Kuppen,et al.  The immunological consequences of photodynamic treatment of cancer, a literature review. , 2003, Immunobiology.

[289]  Kazunori Kataoka,et al.  Light-harvesting ionic dendrimer porphyrins as new photosensitizers for photodynamic therapy. , 2003, Bioconjugate chemistry.

[290]  Beat Ernst,et al.  Drug discovery today. , 2003, Current topics in medicinal chemistry.

[291]  Zheng Huang,et al.  Improvement of Tumor Response by Manipulation of Tumor Oxygenation During Photodynamic Therapy¶ , 2002, Photochemistry and photobiology.

[292]  Shraboni Das,et al.  Inorganic-organic hybrid nanoparticles from n-octyl triethoxy silane. , 2002, Journal of colloid and interface science.

[293]  L. Arnaut,et al.  New Halogenated Phenylbacteriochlorins and Their Efficiency in Singlet-Oxygen Sensitization‡ , 2002 .

[294]  C. Eijk,et al.  Inorganic scintillators in medical imaging. , 2002 .

[295]  Dai Fukumura,et al.  Vascular accumulation of a novel photosensitizer, MV6401, causes selective thrombosis in tumor vessels after photodynamic therapy. , 2002, Cancer research.

[296]  Michael S Patterson,et al.  Direct Near-infrared Luminescence Detection of Singlet Oxygen Generated by Photodynamic Therapy in Cells In Vitro and Tissues In Vivo¶ , 2002, Photochemistry and photobiology.

[297]  D. A. Russell,et al.  Generation of Cytotoxic Singlet Oxygen via Phthalocyanine-Stabilized Gold Nanoparticles: A Potential Delivery Vehicle for Photodynamic Therapy , 2002 .

[298]  Y. Nosaka,et al.  Behavior of superoxide radicals formed on TiO2 powder photocatalysts studied by a chemiluminescent probe method , 2002 .

[299]  R. Gurny,et al.  State of the art in the delivery of photosensitizers for photodynamic therapy. , 2002, Journal of photochemistry and photobiology. B, Biology.

[300]  Nancy L Oleinick,et al.  The role of apoptosis in response to photodynamic therapy: what, where, why, and how , 2002, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[301]  H. Nakanishi,et al.  Synthesis and biological studies of 5-aminolevulinic acid-containing dendrimers for photodynamic therapy. , 2001, Bioconjugate chemistry.

[302]  C. Rothmann,et al.  Nuclear transport of photosensitizers during photosensitization and oxidative stress , 2001, Biology of the cell.

[303]  S. Hackbarth,et al.  Photophysical properties of pheophorbide- a-substituted diaminobutane poly-propylene-imine dendrimer , 2001 .

[304]  K. Avgoustakis,et al.  Effect of dose on the biodistribution and pharmacokinetics of PLGA and PLGA-mPEG nanoparticles. , 2001, International journal of pharmaceutics.

[305]  Thomas J. Dougherty,et al.  Basic principles of photodynamic therapy , 2001 .

[306]  C. Tanielian,et al.  Quantum yield of singlet oxygen production by monomeric and aggregated forms of hematoporphyrin derivative. , 2001, Free radical biology & medicine.

[307]  E. Hull,et al.  Porphyrin Bleaching and PDT-induced Spectral Changes are Irradiance Dependent in ALA-sensitized Normal Rat Skin In Vivo¶ , 2001, Photochemistry and photobiology.

[308]  C J Gomer,et al.  Antiangiogenic treatment enhances photodynamic therapy responsiveness in a mouse mammary carcinoma. , 2000, Cancer research.

[309]  M. Sentjurc,et al.  In vivo EPR of topical delivery of a hydrophilic substance encapsulated in multilamellar liposomes applied to the skin of hairless and normal mice. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[310]  P. Alexandridis,et al.  Physicochemical aspects of drug delivery and release from polymer-based colloids , 2000 .

[311]  H. Maeda,et al.  Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[312]  Michele T. Cooper,et al.  Photofrin photodynamic therapy can significantly deplete or preserve oxygenation in human basal cell carcinomas during treatment, depending on fluence rate. , 2000, Cancer research.

[313]  Allen Cm,et al.  Role of activated oxygen species in photodynamic therapy. , 2000 .

[314]  J. Taillefer,et al.  Preparation and characterization of pH-responsive polymeric micelles for the delivery of photosensitizing anticancer drugs. , 2000, Journal of pharmaceutical sciences.

[315]  N. Oleinick,et al.  The photobiology of photodynamic therapy: cellular targets and mechanisms. , 1998, Radiation research.

[316]  Zhongdang Xiao,et al.  Photoexcited TiO2 nanoparticles through •OH-radicals induced malignant cells to necrosis , 1998 .

[317]  P. Ratcliffe,et al.  Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. , 1998, The Journal of experimental biology.

[318]  R. Steiner,et al.  Basic reaction mechanisms of hydrophilic and lipophilic photosensitisers in photodynamic tumour treatment , 1998 .

[319]  Y. Ikada,et al.  Photodynamic Effect of Polyethylene Glycol–modified Fullerene on Tumor , 1997, Japanese journal of cancer research : Gann.

[320]  J. Zhang,et al.  Ultrafast Studies of Electron Dynamics in Semiconductor and Metal Colloidal Nanoparticles: Effects of Size and Surface , 1997 .

[321]  M. Shive,et al.  Biodegradation and biocompatibility of PLA and PLGA microspheres , 1997 .

[322]  Yuan Chunwei,et al.  The Study of the Photokilling Effect and Mechanism of Ultrafine TiO_2 Particles on U937 Cells , 1997 .

[323]  T. Hasan,et al.  A theoretical study of light fractionation and dose-rate effects in photodynamic therapy. , 1997, Radiation research.

[324]  H. Zimmermann,et al.  Selective photosensitization of mitochondria in HeLa cells by cationic Zn (II) phthalocyanines with lipophilic side-chains. , 1997, Journal of photochemistry and photobiology. B, Biology.

[325]  E. Reddi,et al.  Role of delivery vehicles for photosensitizers in the photodynamic therapy of tumours. , 1997, Journal of photochemistry and photobiology. B, Biology.

[326]  Jun-Jie Yin,et al.  Oxidative damage to nucleic acids photosensitized by titanium dioxide. , 1997, Free radical biology & medicine.

[327]  R. Boyle,et al.  Structure and Biodistribution Relationships of Photodynamic Sensitizers * , 1996, Photochemistry and photobiology.

[328]  J. Rousseau,et al.  Photodynamic therapy of tumours with hexadecafluoro zinc phthalocyanine formulated in PEG‐coated poly(lactic acid) nanoparticles , 1996, International journal of cancer.

[329]  Q. Peng,et al.  Correlation of subcellular and intratumoral photosensitizer localization with ultrastructural features after photodynamic therapy. , 1996, Ultrastructural pathology.

[330]  T. Hasan,et al.  The effects of aggregation, protein binding and cellular incorporation on the photophysical properties of benzoporphyrin derivative monoacid ring A (BPDMA). , 1995, Journal of photochemistry and photobiology. B, Biology.

[331]  F. Ricchelli Photophysical properties of porphyrins in biological membranes. , 1995, Journal of photochemistry and photobiology. B, Biology.

[332]  C. Rhodes,et al.  Preparation and characterization of liposomes as therapeutic delivery systems: a review. , 1995, Pharmaceutica acta Helvetiae.

[333]  G. Semenza,et al.  Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[334]  J. Rousseau,et al.  PEG‐coated Poly(lactic acid) Nanoparticles for the Delivery of Hexadecafluoro Zinc Phthalocyanine to EMT‐6 Mouse Mammary Tumours , 1995, The Journal of pharmacy and pharmacology.

[335]  G. Semenza,et al.  Purification and Characterization of Hypoxia-inducible Factor 1 (*) , 1995, The Journal of Biological Chemistry.

[336]  A. Fujishima,et al.  Photokilling of T-24 human bladder cancer cells with titanium dioxide. , 1994, British Journal of Cancer.

[337]  A. Bangham Liposomes: the Babraham connection. , 1993, Chemistry and physics of lipids.

[338]  B. Henderson,et al.  Implications of a pre-existing tumor hypoxic fraction on photodynamic therapy. , 1992, The Journal of surgical research.

[339]  A. Fujishima,et al.  Induction of cytotoxicity by photoexcited TiO2 particles. , 1992, Cancer research.

[340]  A. Fujishima,et al.  Increment of photocatalytic killing of cancer cells using TiO2 with the aid of superoxide dismutase , 1992 .

[341]  T. Dougherty,et al.  HOW DOES PHOTODYNAMIC THERAPY WORK? , 1992, Photochemistry and photobiology.

[342]  A. Gabizon,et al.  Sterically stabilized liposomes: a hypothesis on the molecular origin of the extended circulation times. , 1991, Biochimica et biophysica acta.

[343]  K. Berg,et al.  THE PHOTODEGRADATION OF PORPHYRINS IN CELLS CAN BE USED TO ESTIMATE THE LIFETIME OF SINGLET OXYGEN , 1991, Photochemistry and photobiology.

[344]  A. Fujishima,et al.  Photokilling of Malignant Cells with Ultrafine TiO2 Powder , 1991 .

[345]  P Nieuwenhuis,et al.  Enzymatic activity toward poly(L-lactic acid) implants. , 1990, Journal of biomedical materials research.

[346]  S. Jacques,et al.  PENETRATION OF LIGHT INTO THE UTERUS OF PREGNANT MAMMALS , 1987, Photochemistry and photobiology.

[347]  A. Fujishima Behavior of tumor cells on photoexcited semiconductor surface , 1986 .

[348]  G. Birrenbach,et al.  Polymerized micelles and their use as adjuvants in immunology. , 1976, Journal of pharmaceutical sciences.

[349]  T J Dougherty,et al.  Photoradiation therapy. II. Cure of animal tumors with hematoporphyrin and light. , 1975, Journal of the National Cancer Institute.

[350]  A. Fujishima,et al.  Electrochemical Photolysis of Water at a Semiconductor Electrode , 1972, Nature.

[351]  W. Stöber,et al.  Controlled growth of monodisperse silica spheres in the micron size range , 1968 .

[352]  William F. Meggers,et al.  Spectroscopic properties of rare earths , 1965 .