CONSEXPO 3.0, consumer exposure and uptake models

The report provides a modelling approach to consumer exposure to chemicals, based on mathematical contact, exposure and uptake models. For each route of exposure, a number of exposure and uptake models are included. A general framework joins the exposure and uptake models selected by the user. By combining different models and different routes, the program allows for many consumer products. The program allows for stochastic parameters, to include variability and uncertainty. The program calculates the resulting exposure and uptake distributions, and allows any percentile to be calculated. This program is linked to a database, which will contain predefined exposure and uptake models for categories of product, for example paints or pest control products. The program reports local exposure concentrations and systemic doses on the acute and semichronic time scale. These include the mean event concentration, the yearly averaged concentration, the fraction taken up, the amount taken up during a year (per route and summed) and the uptake per kilogram body weight per day.