Eye movements in brainstem lesions.

The eye movements of 10 patients with brainstem lesions were examined, using an electro-oculo-graphic technique. An analysis was made of the responses in the following tests: smooth pursuit, saccade, rotation, optokinetic, optovestibular and caloric. Chief interest was directed towards the peak velocity. The results were compared with the corresponding velocities in 20 normal subjects. In the same patient, one or several types of eye movements could be normal, while others were pathological. In the whole group, voluntary eye movements (smooth pursuits and voluntary saccades) were more vulnerable than reflexive ones (nystagmus). Next to the smooth pursuit test and the voluntary saccade test, the optovestibular test was the most sensitive in discriminating patients with brainstem lesions from normal subject.

[1]  B Cohen,et al.  Brainstem mechanisms for rapid and slow eye movements. , 1978, Annual review of physiology.

[2]  I. Pyykkö,et al.  Velocity patterns of rapid eye movements. , 1980, Acta oto-laryngologica.

[3]  B. Cohen,et al.  Relationship of electrical activity in pontine reticular formation and lateral geniculate body to rapid eye movements. , 1968, Journal of neurophysiology.

[4]  G. Jones,et al.  Frequency—response analysis of central vestibular unit activity resulting from rotational stimulation of the semicircular canals , 1971, The Journal of physiology.

[5]  A. Fuchs,et al.  Activity of brain stem neurons during eye movements of alert monkeys. , 1972, Journal of neurophysiology.

[6]  M. B. Bender,et al.  Electrooculographic syndrome in monkeys after pontine reticular formation lesions. , 1968, Archives of neurology.

[7]  J. Sharpe,et al.  Control of the saccadic and smooth pursuit systems after cerebral hemidecortication. , 1979, Brain : a journal of neurology.

[8]  W. Hoyt,et al.  SUPRANUCLEAR DISORDERS OF OCULAR CONTROL SYSTEMS IN MAN: Clinical, Anatomical, and Physiological Correlations—1969 , 1971 .

[9]  H. Shimazu Vestibulo-oculomotor relations: dynamic responses. , 1972, Progress in Brain Research.

[10]  D. Robinson The mechanics of human smooth pursuit eye movement. , 1965, The Journal of physiology.

[11]  E. Keller Participation of medial pontine reticular formation in eye movement generation in monkey. , 1974, Journal of neurophysiology.

[12]  L Schalén,et al.  Quantification of tracking eye movements in normal subjects. , 1980, Acta oto-laryngologica.

[13]  R. Baloh,et al.  Eye-Tracking and Optokinetic Nystagmus , 1977, Annals of Otology, Rhinology and Laryngology.

[14]  R. Baloh,et al.  The saccade velocity test , 1975, Neurology.