Neurotrophin and synaptogenesis

[1]  W. Guo,et al.  Differential effects of transient and sustained activation of BDNF‐TrkB signaling , 2018, Developmental neurobiology.

[2]  C. Liston,et al.  The BDNF Val66Met Prodomain Disassembles Dendritic Spines Altering Fear Extinction Circuitry and Behavior , 2018, Neuron.

[3]  Jinzhi Lei,et al.  Underlying Mechanisms of Cooperativity, Input Specificity, and Associativity of Long-Term Potentiation Through a Positive Feedback of Local Protein Synthesis , 2018, Front. Comput. Neurosci..

[4]  Lars E. Borm,et al.  Molecular Architecture of the Mouse Nervous System , 2018, Cell.

[5]  Jing Wang,et al.  NMR backbone resonance assignments of the prodomain variants of BDNF in the urea denatured state , 2018, Biomolecular NMR assignments.

[6]  Se-Young Choi.  Synaptic and circuit development of the primary sensory cortex , 2018, Experimental & Molecular Medicine.

[7]  Markus A Stahlberg,et al.  Visualizing BDNF cell-to-cell transfer reveals astrocytes are the primary recipient of neuronal BDNF , 2018, bioRxiv.

[8]  M. Kojima,et al.  BDNF pro-peptide: a novel synaptic modulator generated as an N-terminal fragment from the BDNF precursor by proteolytic processing , 2017, Neural regeneration research.

[9]  K. Martinowich,et al.  BDNF at the Synapse: Why Location Matters , 2017, Molecular Psychiatry.

[10]  S. Sajikumar,et al.  ‘Tagging’ along memories in aging: Synaptic tagging and capture mechanisms in the aged hippocampus , 2017, Ageing Research Reviews.

[11]  N. Unsain,et al.  Growth factors and hormones pro‐peptides: the unexpected adventures of the BDNF prodomain , 2017, Journal of neurochemistry.

[12]  Manju Sasi,et al.  Neurobiology of local and intercellular BDNF signaling , 2017, Pflügers Archiv - European Journal of Physiology.

[13]  E. Castrén,et al.  Neuronal plasticity and neurotrophic factors in drug responses , 2017, Molecular Psychiatry.

[14]  N. Berardi,et al.  Peri-Synaptic Glia Recycles Brain-Derived Neurotrophic Factor for LTP Stabilization and Memory Retention , 2016, Neuron.

[15]  M. Chao,et al.  Deletion of Neurotrophin Signaling through the Glucocorticoid Receptor Pathway Causes Tau Neuropathology , 2016, Scientific Reports.

[16]  C. Pariante,et al.  The human BDNF gene: peripheral gene expression and protein levels as biomarkers for psychiatric disorders , 2016, Translational psychiatry.

[17]  F. Jeanneteau,et al.  Timing and crosstalk of glucocorticoid signaling with cytokines, neurotransmitters and growth factors. , 2016, Pharmacological research.

[18]  F. Bronfman,et al.  Cellular and molecular mechanisms regulating neuronal growth by brain‐derived neurotrophic factor , 2016, Cytoskeleton.

[19]  J. McNamara,et al.  Autocrine BDNF–TrkB signalling within a single dendritic spine , 2016, Nature.

[20]  J. McNamara,et al.  Rho GTPase complementation underlies BDNF-dependent homo- and heterosynaptic plasticity , 2016, Nature.

[21]  E. Sibille,et al.  The Role of BDNF in Age-Dependent Changes of Excitatory and Inhibitory Synaptic Markers in the Human Prefrontal Cortex , 2016, Neuropsychopharmacology.

[22]  Wei Jiang,et al.  BDNF pro-peptide regulates dendritic spines via caspase-3 , 2016, Cell Death and Disease.

[23]  E. Masliah,et al.  Glutamatergic axon-derived BDNF controls GABAergic synaptic differentiation in the cerebellum , 2016, Scientific Reports.

[24]  K. Martinowich,et al.  Activity-dependent signaling: influence on plasticity in circuits controlling fear-related behavior , 2016, Current Opinion in Neurobiology.

[25]  F. Jeanneteau,et al.  PROBDNF BIOLOGY AND EMERGING ROLES IN THE CNS: THE UNEXPECTED JOURNEY OF PRONEUROTROPHINS , 2015 .

[26]  K. Bath,et al.  Neurotrophic-priming of glucocorticoid receptor signaling is essential for neuronal plasticity to stress and antidepressant treatment , 2015, Proceedings of the National Academy of Sciences.

[27]  Beth Stevens,et al.  Do glia drive synaptic and cognitive impairment in disease? , 2015, Nature Neuroscience.

[28]  S. Nelson,et al.  Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders , 2015, Neuron.

[29]  J. Yates,et al.  The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA Receptors , 2015, Neuron.

[30]  M. Poo,et al.  Activity-dependent BDNF release via endocytic pathways is regulated by synaptotagmin-6 and complexin , 2015, Proceedings of the National Academy of Sciences.

[31]  S. Yamawaki,et al.  BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met , 2015, Proceedings of the National Academy of Sciences.

[32]  F. Polleux,et al.  SNAREs Controlling Vesicular Release of BDNF and Development of Callosal Axons. , 2015, Cell reports.

[33]  C. Bramham,et al.  Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK. , 2014, Cell reports.

[34]  F. Perera,et al.  DNA methylation of BDNF as a biomarker of early-life adversity , 2014, Proceedings of the National Academy of Sciences.

[35]  Eduardo D. Martín,et al.  Neurotrophin receptor p75(NTR) mediates Huntington's disease-associated synaptic and memory dysfunction. , 2014, The Journal of clinical investigation.

[36]  G. Eichele,et al.  SorCS2 Regulates Dopaminergic Wiring and Is Processed into an Apoptotic Two-Chain Receptor in Peripheral Glia , 2014, Neuron.

[37]  Wei Guo,et al.  Neuronal activity alters BDNF–TrkB signaling kinetics and downstream functions , 2014, Journal of Cell Science.

[38]  Lauren C Harte-Hargrove,et al.  proBDNF negatively regulates neuronal remodeling, synaptic transmission, and synaptic plasticity in hippocampus. , 2014, Cell reports.

[39]  Sarah Aufmkolk,et al.  High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons , 2014, Front. Cell. Neurosci..

[40]  M. Bennett,et al.  Stress and trauma: BDNF control of dendritic-spine formation and regression , 2014, Progress in Neurobiology.

[41]  C. Bramham,et al.  BDNF mechanisms in late LTP formation: A synthesis and breakdown , 2014, Neuropharmacology.

[42]  J. Yates,et al.  Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor , 2013, Cell.

[43]  E. Schuman,et al.  Deep Sequencing and High-Resolution Imaging Reveal Compartment-Specific Localization of Bdnf mRNA in Hippocampal Neurons , 2013, Science Signaling.

[44]  M. Greenberg,et al.  The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition , 2013, Nature.

[45]  R. Rodriguiz,et al.  Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice , 2013, Proceedings of the National Academy of Sciences.

[46]  F. Lee,et al.  Val66Met Polymorphism of BDNF Alters Prodomain Structure to Induce Neuronal Growth Cone Retraction , 2013, Nature Communications.

[47]  M. Garabedian,et al.  Brain-Derived Neurotrophic Factor Signaling Rewrites the Glucocorticoid Transcriptome via Glucocorticoid Receptor Phosphorylation , 2013, Molecular and Cellular Biology.

[48]  K. Bath,et al.  Stress effects on BDNF expression: Effects of age, sex, and form of stress , 2013, Neuroscience.

[49]  M. Chao,et al.  Are BDNF and glucocorticoid activities calibrated? , 2013, Neuroscience.

[50]  J. Cloutier,et al.  Relationship between BDNF expression in major striatal afferents, striatum morphology and motor behavior in the R6/2 mouse model of Huntington's disease , 2013, Genes, brain, and behavior.

[51]  Catarina Gomes,et al.  Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia , 2013, Journal of Neuroinflammation.

[52]  Mu-ming Poo,et al.  Neurotrophin regulation of neural circuit development and function , 2012, Nature Reviews Neuroscience.

[53]  E. Castrén,et al.  Mapping of the Interaction Site between Sortilin and the p75 Neurotrophin Receptor Reveals a Regulatory Role for the Sortilin Intracellular Domain in p75 Neurotrophin Receptor Shedding and Apoptosis* , 2012, The Journal of Biological Chemistry.

[54]  W. Yung,et al.  TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory , 2012, Nature Neuroscience.

[55]  Byung C. Yoon,et al.  Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair , 2012, Nature Reviews Neuroscience.

[56]  T. Willnow,et al.  Sortilin: a receptor to regulate neuronal viability and function , 2012, Trends in Neurosciences.

[57]  L. Monteggia,et al.  Brain-Derived Neurotrophic Factor and Neuropsychiatric Disorders , 2012, Pharmacological Reviews.

[58]  M. Frotscher,et al.  Jcb: Article , 2022 .

[59]  Francis S Lee,et al.  Impact of the BDNF Val66Met Polymorphism on Cognition , 2012, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[60]  Daniel S Spellman,et al.  Neuronal Growth Cone Retraction Relies on Proneurotrophin Receptor Signaling Through Rac , 2011, Science Signaling.

[61]  E. Tongiorgi,et al.  Spatial segregation of BDNF transcripts enables BDNF to differentially shape distinct dendritic compartments , 2011, Proceedings of the National Academy of Sciences.

[62]  S. Itohara,et al.  Matrix Metalloproteinase-9 Contributes to Kindled Seizure Development in Pentylenetetrazole-Treated Mice by Converting Pro-BDNF to Mature BDNF in the Hippocampus , 2011, The Journal of Neuroscience.

[63]  K. Martinowich,et al.  TrkB as a Potential Synaptic and Behavioral Tag , 2011, The Journal of Neuroscience.

[64]  C. Blobel,et al.  Neuronal Brain-derived Neurotrophic Factor Is Synthesized in Excess, with Levels Regulated by Sortilin-mediated Trafficking and Lysosomal Degradation , 2011, The Journal of Biological Chemistry.

[65]  J. Sweatt,et al.  Epigenetic marking of the BDNF gene by early-life adverse experiences , 2011, Hormones and Behavior.

[66]  Xin-Fu Zhou,et al.  Precursor of Brain-derived Neurotrophic Factor (proBDNF) Forms a Complex with Huntingtin-associated Protein-1 (HAP1) and Sortilin That Modulates proBDNF Trafficking, Degradation, and Processing* , 2011, The Journal of Biological Chemistry.

[67]  S. Sajikumar,et al.  Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase Mζ (PKMζ) , 2011, Proceedings of the National Academy of Sciences.

[68]  M. A. Sutton,et al.  Local Presynaptic Activity Gates Homeostatic Changes in Presynaptic Function Driven by Dendritic BDNF Synthesis , 2010, Neuron.

[69]  M. Yamada,et al.  Postsynaptic Spiking Homeostatically Induces Cell-Autonomous Regulation of Inhibitory Inputs via Retrograde Signaling , 2010, The Journal of Neuroscience.

[70]  Anthony W. Harrington,et al.  Long-Distance Control of Synapse Assembly by Target-Derived NGF , 2010, Neuron.

[71]  K. Bath,et al.  The BDNF Val66Met Polymorphism Impairs NMDA Receptor-Dependent Synaptic Plasticity in the Hippocampus , 2010, The Journal of Neuroscience.

[72]  M. Chao,et al.  Activation of Adenosine A2A Receptors Induces TrkB Translocation and Increases BDNF-Mediated Phospho-TrkB Localization in Lipid Rafts: Implications for Neuromodulation , 2010, The Journal of Neuroscience.

[73]  K. Martin,et al.  Spatially restricting gene expression by local translation at synapses , 2010, Trends in Neurosciences.

[74]  K. Teng,et al.  Understanding proneurotrophin actions: Recent advances and challenges , 2010, Developmental neurobiology.

[75]  S. Cohen-Cory,et al.  Brain‐derived neurotrophic factor and the development of structural neuronal connectivity , 2010, Developmental neurobiology.

[76]  S. Duan,et al.  Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons , 2010, Nature Neuroscience.

[77]  Y. Barde,et al.  Global Deprivation of Brain-Derived Neurotrophic Factor in the CNS Reveals an Area-Specific Requirement for Dendritic Growth , 2010, The Journal of Neuroscience.

[78]  L. Minichiello.  TrkB signalling pathways in LTP and learning , 2009, Nature Reviews Neuroscience.

[79]  Mu-ming Poo,et al.  Long-range retrograde spread of LTP and LTD from optic tectum to retina , 2009, Proceedings of the National Academy of Sciences.

[80]  R. Prosser,et al.  Tissue‐type plasminogen activator‐plasmin‐BDNF modulate glutamate‐induced phase‐shifts of the mouse suprachiasmatic circadian clock in vitro , 2009, The European journal of neuroscience.

[81]  Volkmar Lessmann,et al.  BDNF signaling in the formation, maturation and plasticity of glutamatergic and GABAergic synapses , 2009, Experimental Brain Research.

[82]  J. Baraban,et al.  Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation , 2009, Proceedings of the National Academy of Sciences.

[83]  E. Castrén,et al.  Brain-Derived Neurotrophic Factor Controls Activity-Dependent Maturation of CA1 Synapses by Downregulating Tonic Activationof Presynaptic Kainate Receptors , 2009, The Journal of Neuroscience.

[84]  T. Sejnowski,et al.  NGF Is Essential for Hippocampal Plasticity and Learning , 2009, The Journal of Neuroscience.

[85]  V. Lessmann,et al.  Mechanisms, locations, and kinetics of synaptic BDNF secretion: An update , 2009, Neuroscience Research.

[86]  A. Ogura,et al.  Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival , 2009, Molecular Brain.

[87]  I. Izquierdo,et al.  BDNF Activates mTOR to Regulate GluR1 Expression Required for Memory Formation , 2009, PloS one.

[88]  Xiang Zhang,et al.  Axon Initiation and Growth Cone Turning on Bound Protein Gradients , 2009, The Journal of Neuroscience.

[89]  B. Hempstead,et al.  NRH2 is a trafficking switch to regulate sortilin localization and permit proneurotrophin‐induced cell death , 2009, The EMBO journal.

[90]  Andrea Disanza,et al.  Eps8 Regulates Axonal Filopodia in Hippocampal Neurons in Response to Brain-Derived Neurotrophic Factor (BDNF) , 2009, PLoS biology.

[91]  M. Jackson,et al.  Synaptotagmin-IV Modulates Synaptic Function and LTP by Regulating BDNF Release , 2009, Nature Neuroscience.

[92]  Kaoru Inokuchi,et al.  Input-Specific Spine Entry of Soma-Derived Vesl-1S Protein Conforms to Synaptic Tagging , 2009, Science.

[93]  J. Sweatt,et al.  Lasting Epigenetic Influence of Early-Life Adversity on the BDNF Gene , 2009, Biological Psychiatry.

[94]  S. Beggs,et al.  P2X4-Receptor-Mediated Synthesis and Release of Brain-Derived Neurotrophic Factor in Microglia Is Dependent on Calcium and p38-Mitogen-Activated Protein Kinase Activation , 2009, The Journal of Neuroscience.

[95]  C. Siao,et al.  Neuronal release of proBDNF , 2009, Nature Neuroscience.

[96]  B. Lu,et al.  Control of extracellular cleavage of ProBDNF by high frequency neuronal activity , 2009, Proceedings of the National Academy of Sciences.

[97]  K. Bath,et al.  Endogenous Truncated TrkB.T1 Receptor Regulates Neuronal Complexity and TrkB Kinase Receptor Function In Vivo , 2009, The Journal of Neuroscience.

[98]  M. Greenberg,et al.  A Biological Function for the Neuronal Activity-Dependent Component of Bdnf Transcription in the Development of Cortical Inhibition , 2008, Neuron.

[99]  Athar N. Malik,et al.  Activity-dependent regulation of inhibitory synapse development by Npas4 , 2008, Nature.

[100]  M. Bergami,et al.  Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes , 2008, The Journal of cell biology.

[101]  P. Wahle,et al.  Neuronal activity and TrkB ligands influence Kv3.1b and Kv3.2 expression in developing cortical interneurons , 2008, Neuroscience.

[102]  C. Bramham.  Local protein synthesis, actin dynamics, and LTP consolidation , 2008, Current Opinion in Neurobiology.

[103]  D. O'Leary,et al.  p75NTR Mediates Ephrin-A Reverse Signaling Required for Axon Repulsion and Mapping , 2008, Neuron.

[104]  N. Woo,et al.  Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons , 2008, Cell.

[105]  J. Gaiarsa,et al.  Backpropagating Action Potentials Trigger Dendritic Release of BDNF during Spontaneous Network Activity , 2008, The Journal of Neuroscience.

[106]  G. Westbrook,et al.  Neurotrophin-Dependent Dendritic Filopodial Motility: A Convergence on PI3K Signaling , 2008, The Journal of Neuroscience.

[107]  Michael E Greenberg,et al.  Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration , 2008, Nature Neuroscience.

[108]  T. Mittmann,et al.  Impaired GABAergic inhibition in the visual cortex of brain‐derived neurotrophic factor heterozygous knockout mice , 2008, The Journal of physiology.

[109]  G. Turrigiano,et al.  Rapid Synaptic Scaling Induced by Changes in Postsynaptic Firing , 2008, Neuron.

[110]  M. Garabedian,et al.  Activation of Trk neurotrophin receptors by glucocorticoids provides a neuroprotective effect , 2008, Proceedings of the National Academy of Sciences.

[111]  Haruo Kasai,et al.  Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines , 2008, Science.

[112]  K. Gray,et al.  Activation of pro‐BDNF by the pericellular serine protease plasmin , 2008, FEBS letters.

[113]  K. Christian,et al.  BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory? , 2008, Neurobiology of Learning and Memory.

[114]  K. Harris.  Stability of the fittest: organizing learning through retroaxonal signals , 2008, Trends in Neurosciences.

[115]  E. Tongiorgi,et al.  BDNF mRNA splice variants display activity-dependent targeting to distinct hippocampal laminae , 2008, Molecular and Cellular Neuroscience.

[116]  Yves-Alain Barde,et al.  Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF , 2008, Nature Neuroscience.

[117]  J. Nyengaard,et al.  Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury , 2007, Nature Neuroscience.

[118]  Tanja Brigadski,et al.  Postsynaptic Secretion of BDNF and NT-3 from Hippocampal Neurons Depends on Calcium–Calmodulin Kinase II Signaling and Proceeds via Delayed Fusion Pore Opening , 2007, The Journal of Neuroscience.

[119]  T. Tsumoto,et al.  A Local Reduction in Cortical GABAergic Synapses after a Loss of Endogenous Brain-Derived Neurotrophic Factor, as Revealed by Single-Cell Gene Knock-Out Method , 2007, The Journal of Neuroscience.

[120]  Joseph A. Gogos,et al.  Genetic Modulation of BDNF Signaling Affects the Outcome of Axonal Competition In Vivo , 2007, Current Biology.

[121]  G. Turrigiano.  Homeostatic signaling: the positive side of negative feedback , 2007, Current Opinion in Neurobiology.

[122]  E. Amaya,et al.  BDNF promotes target innervation of Xenopus mandibular trigeminal axons in vivo , 2007, BMC Developmental Biology.

[123]  Li I. Zhang,et al.  Heterosynaptic Scaling of Developing GABAergic Synapses: Dependence on Glutamatergic Input and Developmental Stage , 2007, The Journal of Neuroscience.

[124]  M. Amaral,et al.  TRPC3 Channels Are Necessary for Brain-Derived Neurotrophic Factor to Activate a Nonselective Cationic Current and to Induce Dendritic Spine Formation , 2007, The Journal of Neuroscience.

[125]  M. Poo,et al.  Excitatory GABA Action Is Essential for Morphological Maturation of Cortical Neurons In Vivo , 2007, The Journal of Neuroscience.

[126]  M. Chao,et al.  The Tyrosine Kinase Fyn Determines the Localization of TrkB Receptors in Lipid Rafts , 2007, The Journal of Neuroscience.

[127]  N. Ip,et al.  Cyclin-Dependent Kinase 5 Links Extracellular Cues to Actin Cytoskeleton During Dendritic Spine Development , 2007, Cell adhesion & migration.

[128]  S. Itohara,et al.  Impaired Cerebellar Development and Function in Mice Lacking CAPS2, a Protein Involved in Neurotrophin Release , 2007, The Journal of Neuroscience.

[129]  N. Ip,et al.  Cdk5 Is Involved in BDNF-Stimulated Dendritic Growth in Hippocampal Neurons , 2007, PLoS biology.

[130]  A. Konnerth,et al.  Requirement of TrkB for synapse elimination in developing cerebellar Purkinje cells , 2007, Brain cell biology.

[131]  A. Merighi,et al.  Costorage of BDNF and neuropeptides within individual dense‐core vesicles in central and peripheral neurons , 2007, Developmental neurobiology.

[132]  T. Bonhoeffer,et al.  Endogenous Brain-Derived Neurotrophic Factor Triggers Fast Calcium Transients at Synapses in Developing Dendrites , 2007, The Journal of Neuroscience.

[133]  G. Edelman,et al.  BDNF induces widespread changes in synaptic protein content and up-regulates components of the translation machinery: an analysis using high-throughput proteomics. , 2007, Journal of proteome research.

[134]  F. Lee,et al.  Single-Cell Characterization of Retrograde Signaling by Brain-Derived Neurotrophic Factor , 2006, The Journal of Neuroscience.

[135]  Kaia Palm,et al.  Mouse and rat BDNF gene structure and expression revisited , 2006, Journal of neuroscience research.

[136]  C. Siao,et al.  Genetic Variant BDNF (Val66Met) Polymorphism Alters Anxiety-Related Behavior , 2006, Science.

[137]  L. Reichardt,et al.  Neurotrophin-regulated signalling pathways , 2006, Philosophical Transactions of the Royal Society B: Biological Sciences.

[138]  M. Bergami,et al.  Hippocampal neurons recycle BDNF for activity‐dependent secretion and LTP maintenance , 2006, The EMBO journal.

[139]  P. Greengard,et al.  Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology , 2006, Nature.

[140]  P. Stanton,et al.  BDNF increases release probability and the size of a rapidly recycling vesicle pool within rat hippocampal excitatory synapses , 2006, The Journal of physiology.

[141]  O. Arancio,et al.  BDNF-mediated neurotransmission relies upon a myosin VI motor complex , 2006, Nature Neuroscience.

[142]  D. Lewis,et al.  Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood , 2006, Molecular Psychiatry.

[143]  L. Reichardt,et al.  BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin–β-catenin interactions , 2006, The Journal of cell biology.

[144]  J. Meier,et al.  Altered Balance of Glutamatergic/GABAergic Synaptic Input and Associated Changes in Dendrite Morphology after BDNF Expression in BDNF-Deficient Hippocampal Neurons , 2006, The Journal of Neuroscience.

[145]  W. Mobley,et al.  TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology , 2006, Proceedings of the National Academy of Sciences.

[146]  B. Matthews,et al.  BDNF increases synapse density in dendrites of developing tectal neurons in vivo , 2006, Development.

[147]  P. Worley,et al.  Homer proteins: implications for neuropsychiatric disorders , 2006, Current Opinion in Neurobiology.

[148]  G. Collingridge,et al.  Functional Maturation of CA1 Synapses Involves Activity-Dependent Loss of Tonic Kainate Receptor-Mediated Inhibition of Glutamate Release , 2006, Neuron.

[149]  S. Duan,et al.  Activity-Induced Rapid Synaptic Maturation Mediated by Presynaptic Cdc42 Signaling , 2006, Neuron.

[150]  V. Coppola,et al.  A kinase-deficient TrkC receptor isoform activates Arf6–Rac1 signaling through the scaffold protein tamalin , 2006, The Journal of cell biology.

[151]  M. Hayashi,et al.  TrkB-T1 regulates the RhoA signaling and actin cytoskeleton in glioma cells. , 2006, Biochemical and biophysical research communications.

[152]  T. Bonhoeffer,et al.  Hippocampal Long-Term Potentiation Is Supported by Presynaptic and Postsynaptic Tyrosine Receptor Kinase B-Mediated Phospholipase Cγ Signaling , 2006, The Journal of Neuroscience.

[153]  J. Bamburg,et al.  Cdc42 participates in the regulation of ADF/cofilin and retinal growth cone filopodia by brain derived neurotrophic factor. , 2006, Journal of neurobiology.

[154]  E. Tongiorgi,et al.  What is the biological significance of BDNF mRNA targeting in the dendrites? , 2006, Molecular Neurobiology.

[155]  B. Hempstead.  Dissecting the diverse actions of pro- and mature neurotrophins. , 2006, Current Alzheimer research.

[156]  J. J. Couey,et al.  Postsynaptic TrkB signaling has distinct roles in spine maintenance in adult visual cortex and hippocampus. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[157]  Michael E. Greenberg,et al.  A brain-specific microRNA regulates dendritic spine development , 2006, Nature.

[158]  T. Bonhoeffer,et al.  The p75 Neurotrophin Receptor Negatively Modulates Dendrite Complexity and Spine Density in Hippocampal Neurons , 2005, The Journal of Neuroscience.

[159]  E. Kandel,et al.  Gene Expression Profiling of Facilitated L-LTP in VP16-CREB Mice Reveals that BDNF Is Critical for the Maintenance of LTP and Its Synaptic Capture , 2005, Neuron.

[160]  A. Nikolakopoulou,et al.  BDNF stabilizes synapses and maintains the structural complexity of optic axons in vivo , 2005, Development.

[161]  B. Lu,et al.  Activity-dependent modulation of the BDNF receptor TrkB: mechanisms and implications , 2005, Trends in Neurosciences.

[162]  Y. Ikegaya,et al.  To BDNF or Not to BDNF: That Is the Epileptic Hippocampus , 2005, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[163]  Bai Lu,et al.  Activation of p75NTR by proBDNF facilitates hippocampal long-term depression , 2005, Nature Neuroscience.

[164]  D. G. Herrera,et al.  Sortilin Controls Intracellular Sorting of Brain-Derived Neurotrophic Factor to the Regulated Secretory Pathway , 2005, The Journal of Neuroscience.

[165]  Barbara L. Hempstead,et al.  ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTR and Sortilin , 2005, The Journal of Neuroscience.

[166]  Ning Li,et al.  Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor , 2005, Nature.

[167]  B. Luikart,et al.  TrkB Has a Cell-Autonomous Role in the Establishment of Hippocampal Schaffer Collateral Synapses , 2005, The Journal of Neuroscience.

[168]  Xi Chen,et al.  A Chemical-Genetic Approach to Studying Neurotrophin Signaling , 2005, Neuron.

[169]  I. Black,et al.  Early Presynaptic and Late Postsynaptic Components Contribute Independently to Brain-Derived Neurotrophic Factor-Induced Synaptic Plasticity , 2005, The Journal of Neuroscience.

[170]  G. Turrigiano,et al.  Postsynaptic Expression of Homeostatic Plasticity at Neocortical Synapses , 2005, The Journal of Neuroscience.

[171]  Petti T. Pang,et al.  Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons , 2005, Nature Neuroscience.

[172]  T. Bonhoeffer,et al.  Bidirectional Activity-Dependent Morphological Plasticity in Hippocampal Neurons , 2004, Neuron.

[173]  B. Holtmann,et al.  Truncated TrkB receptor-induced outgrowth of dendritic filopodia involves the p75 neurotrophin receptor , 2004, Journal of Cell Science.

[174]  Spartaco Santi,et al.  Induction of long-term potentiation and depression is reflected by corresponding changes in secretion of endogenous brain-derived neurotrophic factor. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[175]  Michael Davis,et al.  Differential regulation of brain-derived neurotrophic factor transcripts during the consolidation of fear learning. , 2004, Learning & memory.

[176]  J. Kapur,et al.  Synaptic and extrasynaptic localization of brain‐derived neurotrophic factor and the tyrosine kinase B receptor in cultured hippocampal neurons , 2004, The Journal of comparative neurology.

[177]  D. Wells,et al.  Rapid, Activity-Induced Increase in Tissue Plasminogen Activator Is Mediated by Metabotropic Glutamate Receptor-Dependent mRNA Translation , 2004, The Journal of Neuroscience.

[178]  Petti T. Pang,et al.  Cleavage of proBDNF by tPA/Plasmin Is Essential for Long-Term Hippocampal Plasticity , 2004, Science.

[179]  M. Fainzilber,et al.  Multi‐tasking by the p75 neurotrophin receptor: sortilin things out? , 2004, EMBO reports.

[180]  Wen G. Chen,et al.  BDNF Regulates the Translation of a Select Group of mRNAs by a Mammalian Target of Rapamycin-Phosphatidylinositol 3-Kinase-Dependent Pathway during Neuronal Development , 2004, The Journal of Neuroscience.

[181]  Fabrice P Cordelières,et al.  Huntingtin Controls Neurotrophic Support and Survival of Neurons by Enhancing BDNF Vesicular Transport along Microtubules , 2004, Cell.

[182]  M. Yamada,et al.  BDNF locally potentiates GABAergic presynaptic machineries: target-selective circuit inhibition. , 2004, Cerebral cortex.

[183]  Mu-ming Poo,et al.  Rapid BDNF-induced retrograde synaptic modification in a developing retinotectal system , 2004, Nature.

[184]  G. Lynch,et al.  A Novel Mechanism for the Facilitation of Theta-Induced Long-Term Potentiation by Brain-Derived Neurotrophic Factor , 2004, The Journal of Neuroscience.

[185]  J. Gorski,et al.  Early Striatal Dendrite Deficits followed by Neuron Loss with Advanced Age in the Absence of Anterograde Cortical Brain-Derived Neurotrophic Factor , 2004, The Journal of Neuroscience.

[186]  G. Knott,et al.  Altered Synapse Formation in the Adult Somatosensory Cortex of Brain-Derived Neurotrophic Factor Heterozygote Mice , 2004, The Journal of Neuroscience.

[187]  R. Balice-Gordon,et al.  Postsynaptic TrkB-Mediated Signaling Modulates Excitatory and Inhibitory Neurotransmitter Receptor Clustering at Hippocampal Synapses , 2004, The Journal of Neuroscience.

[188]  H. Schaller,et al.  The three sorCS genes are differentially expressed and regulated by synaptic activity , 2004, Journal of neurochemistry.

[189]  J. Medina,et al.  ERK1/2 activation is necessary for BDNF to increase dendritic spine density in hippocampal CA1 pyramidal neurons. , 2004, Learning & memory.

[190]  Barbara L. Hempstead,et al.  Sortilin is essential for proNGF-induced neuronal cell death , 2004, Nature.

[191]  S. Moss,et al.  Molecular Brain-Derived Neurotrophic Factor Modulates Fast Synaptic Inhibition by Regulating GABAA Receptor Phosphorylation , Activity , and Cell-Surface Stability , 2004 .

[192]  H. Scharfman,et al.  Mini Review , 2004 .

[193]  Arthur Konnerth,et al.  Truncated TrkB-T1 mediates neurotrophin-evoked calcium signalling in glia cells , 2003, Nature.

[194]  T. Tsumoto,et al.  Brain-derived neurotrophic factor-dependent unmasking of “silent” synapses in the developing mouse barrel cortex , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[195]  E. Kandel,et al.  Presynaptic BDNF Required for a Presynaptic but Not Postsynaptic Component of LTP at Hippocampal CA1-CA3 Synapses , 2003, Neuron.

[196]  T. Tsumoto,et al.  Inhibitory But Not Excitatory Cortical Neurons Require Presynaptic Brain-Derived Neurotrophic Factor for Dendritic Development, as Revealed by Chimera Cell Culture , 2003, The Journal of Neuroscience.

[197]  L. Maffei,et al.  Effects of Neurotrophins on Synaptic Protein Expression in the Visual Cortex of Dark-Reared Rats , 2003, The Journal of Neuroscience.

[198]  J. Hjerling-Leffler,et al.  BDNF gene replacement reveals multiple mechanisms for establishing neurotrophin specificity during sensory nervous system development , 2003, Development.

[199]  F. Seil.  TrkB receptor signaling and activity-dependent inhibitory synaptogenesis. , 2003, Histology and histopathology.

[200]  M. Chao,et al.  Neurotrophins and their receptors: A convergence point for many signalling pathways , 2003, Nature Reviews Neuroscience.

[201]  Bai Lu,et al.  BDNF and activity-dependent synaptic modulation. , 2003, Learning & memory.

[202]  M. Egan,et al.  The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function , 2003, Cell.

[203]  J. Voipio,et al.  BDNF-induced TrkB activation down-regulates the K+–Cl− cotransporter KCC2 and impairs neuronal Cl− extrusion , 2002, The Journal of cell biology.

[204]  E. Castrén,et al.  Regulation of TRKB Surface Expression by Brain-derived Neurotrophic Factor and Truncated TRKB Isoforms* , 2002, The Journal of Biological Chemistry.

[205]  A. Konnerth,et al.  Neurotrophin-evoked depolarization requires the sodium channel NaV1.9 , 2002, Nature.

[206]  L. Maffei.  Plasticity in the visual system: role of neurotrophins and electrical activity. , 2002, Archives italiennes de biologie.

[207]  T. Bonhoeffer,et al.  Mechanism of TrkB-Mediated Hippocampal Long-Term Potentiation , 2002, Neuron.

[208]  M. Yamada,et al.  Brain-Derived Neurotrophic Factor Promotes the Maturation of GABAergic Mechanisms in Cultured Hippocampal Neurons , 2002, The Journal of Neuroscience.

[209]  W. Tyler,et al.  From acquisition to consolidation: on the role of brain-derived neurotrophic factor signaling in hippocampal-dependent learning. , 2002, Learning & memory.

[210]  Arthur Konnerth,et al.  Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation , 2002, Science.

[211]  Michael E. Greenberg,et al.  A Calcium-Responsive Transcription Factor, CaRF, that Regulates Neuronal Activity-Dependent Expression of BDNF , 2002, Neuron.

[212]  M. Sheng,et al.  Dentritic spines : structure, dynamics and regulation , 2001, Nature Reviews Neuroscience.

[213]  Barbara L. Hempstead,et al.  Regulation of Cell Survival by Secreted Proneurotrophins , 2001, Science.

[214]  T. Bonhoeffer,et al.  A caged Ab reveals an immediate/instructive effect of BDNF during hippocampal synaptic potentiation , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[215]  W. Tyler,et al.  BDNF Enhances Quantal Neurotransmitter Release and Increases the Number of Docked Vesicles at the Active Zones of Hippocampal Excitatory Synapses , 2001, The Journal of Neuroscience.

[216]  P. Madsen,et al.  The sortilin cytoplasmic tail conveys Golgi–endosome transport and binds the VHS domain of the GGA2 sorting protein , 2001, The EMBO journal.

[217]  N. Seidah,et al.  Biosynthesis and Post-translational Processing of the Precursor to Brain-derived Neurotrophic Factor* , 2001, The Journal of Biological Chemistry.

[218]  R. Wenthold,et al.  Neurotrophins act at presynaptic terminals to activate synapses among cultured hippocampal neurons , 2001, The European journal of neuroscience.

[219]  F. Lee,et al.  Activation of Trk neurotrophin receptors in the absence of neurotrophins , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[220]  E. Levine,et al.  Brain‐derived neurotrophic factor increases activity of NR2B‐containing N‐methyl‐D‐aspartate receptors in excised patches from hippocampal neurons , 2000, Journal of neuroscience research.

[221]  Bai Lu,et al.  Activity- and Ca2+-Dependent Modulation of Surface Expression of Brain-Derived Neurotrophic Factor Receptors in Hippocampal Neurons , 2000, The Journal of cell biology.

[222]  F. Seil,et al.  TrkB Receptor Ligands Promote Activity-Dependent Inhibitory Synaptogenesis , 2000, The Journal of Neuroscience.

[223]  David R Kaplan,et al.  Neurotrophin signal transduction in the nervous system , 2000, Current Opinion in Neurobiology.

[224]  R. Jaenisch,et al.  Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities , 2000, Nature Neuroscience.

[225]  B. Lu,et al.  Neurotrophins and hippocampal synaptic transmission and plasticity , 1999, Journal of neuroscience research.

[226]  L. Maffei,et al.  BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex , 1999, Cell.

[227]  M. Poo,et al.  Gating of BDNF-induced synaptic potentiation by cAMP. , 1999, Science.

[228]  P. Wahle,et al.  Expression of TrkB and TrkC but not BDNF mRNA in neurochemically identified interneurons in rat visual cortex in vivo and in organotypic cultures , 1999, The European journal of neuroscience.

[229]  N. Seidah,et al.  Differential Sorting of Nerve Growth Factor and Brain-Derived Neurotrophic Factor in Hippocampal Neurons , 1999, The Journal of Neuroscience.

[230]  V. Lessmann.  Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS. , 1998, General pharmacology.

[231]  M. Barbacid,et al.  TrkB and TrkC Signaling Are Required for Maturation and Synaptogenesis of Hippocampal Connections , 1998, The Journal of Neuroscience.

[232]  M Segal,et al.  Neurotrophins Induce Formation of Functional Excitatory and Inhibitory Synapses between Cultured Hippocampal Neurons , 1998, The Journal of Neuroscience.

[233]  S. Nelson,et al.  BDNF Has Opposite Effects on the Quantal Amplitude of Pyramidal Neuron and Interneuron Excitatory Synapses , 1998, Neuron.

[234]  H. Lester,et al.  Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[235]  M. Marcinkiewicz,et al.  The pro-protein convertase PC1 is induced in the transected sciatic nerve and is present in cultured Schwann cells: comparison with PC5, furin and PC7, implication in pro-BDNF processing. , 1998, Brain research. Molecular brain research.

[236]  I. Black,et al.  Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N-methyl-D-aspartic acid receptor activity. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[237]  X Wang,et al.  Localized Synaptic Actions of Neurotrophin-4 , 1998, The Journal of Neuroscience.

[238]  I. Black,et al.  Brain-derived neurotrophic factor rapidly enhances phosphorylation of the postsynaptic N-methyl-D-aspartate receptor subunit 1. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[239]  Y. Barde,et al.  The Neurotrophin Receptor p75 Binds Neurotrophin-3 on Sympathetic Neurons with High Affinity and Specificity , 1997, The Journal of Neuroscience.

[240]  G G Turrigiano,et al.  Brain-Derived Neurotrophic Factor Mediates the Activity-Dependent Regulation of Inhibition in Neocortical Cultures , 1997, The Journal of Neuroscience.

[241]  Lawrence C. Katz,et al.  Opposing Roles for Endogenous BDNF and NT-3 in Regulating Cortical Dendritic Growth , 1997, Neuron.

[242]  N. Tommerup,et al.  Molecular Identification of a Novel Candidate Sorting Receptor Purified from Human Brain by Receptor-associated Protein Affinity Chromatography* , 1997, The Journal of Biological Chemistry.

[243]  B. Lu,et al.  Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus , 1996, Nature.

[244]  J. W. Lichtman,et al.  Are Neurotrophins Synaptotrophins? , 1996, Molecular and Cellular Neuroscience.

[245]  Ted Abel,et al.  Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice , 1996, Neuron.

[246]  P. Greengard,et al.  Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[247]  N. Seidah,et al.  Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases , 1996, FEBS letters.

[248]  Y. Barde,et al.  Early Expression of the Nerve Growth Factor Receptor ctrkA in Chick Sympathetic and Sensory Ganglia , 1995, Molecular and Cellular Neuroscience.

[249]  Lawrence C. Katz,et al.  Neurotrophins regulate dendritic growth in developing visual cortex , 1995, Neuron.

[250]  T Bonhoeffer,et al.  Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[251]  Y. Barde,et al.  Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development. , 1995, Development.

[252]  B. Hempstead,et al.  p75 and Trk: A two-receptor system , 1995, Trends in Neurosciences.

[253]  B. Hempstead,et al.  High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors. , 1994, The Journal of biological chemistry.

[254]  G. Dechant,et al.  Specific high-affinity receptors for neurotrophin-3 on sympathetic neurons , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[255]  M. Chao.  Neurotrophin receptors: A window into neuronal differentiation , 1992, Neuron.

[256]  D. Kaplan,et al.  High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor , 1991, Nature.

[257]  R. Oppenheim,et al.  The neurotrophic theory and naturally occurring motoneuron death , 1989, Trends in Neurosciences.

[258]  Y. Barde,et al.  Binding characteristics of brain-derived neurotrophic factor to its receptors on neurons from the chick embryo , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[259]  R. Harris-Warrick,et al.  Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells. , 1979, The Journal of biological chemistry.

[260]  B. Hempstead.  Brain-Derived Neurotrophic Factor: Three Ligands, Many Actions. , 2015, Transactions of the American Clinical and Climatological Association.

[261]  M. Chao,et al.  Trk receptors. , 2014, Handbook of experimental pharmacology.

[262]  S. Humbert,et al.  Maladie de Huntington : signalisation intracellulaire et mort neuronale : Mort cellulaire programmée: Origine(s), mécanismes moléculaires et implications physiopathologiques , 2005 .

[263]  Gianluca Gallo,et al.  Regulation of growth cone actin filaments by guidance cues. , 2004, Journal of neurobiology.

[264]  Mu-ming Poo,et al.  Neurotrophins as synaptic modulators , 2001, Nature Reviews Neuroscience.

[265]  L C Katz,et al.  Neurotrophins and synaptic plasticity. , 1999, Annual review of neuroscience.