— Forty-three cases of cutaneous melanocytic neoplasia in cats were reviewed. Twenty-eight of the 43 neoplasms were histologically benign and 15 were malignant. Behavior was independent of site except that tumors of the eyelid were malignant. Histologic findings of epidermal ulceration, cleanliness of tissue borders, degree of melanization, tumor cell type, and the presence or absence of theques did not differentiate benign from malignant tumors. Junctional activity indicated a high probability of benign behavior while malignant behavior was predicted by a high mitotic index and infiltration of the tumor by lymphoid cells.
Resume— Quarante trois cas de tumeurs melaniques felines ont ete revus. Vingt huit de ces 43 tumeurs etaient histologiquement benignes et 15 malignes. Le comportement etait independant de la localisation de la tumeur, a l'exception des tumeurs des paupieres, toujours malignes. L'observation histologique d'ulceration epidermique, de proprete des bords des tissus, du degre de melanisation, du type cellulaire et de la presence ou de l'absence de theques ne differait pas qu'il s'agisse de tumeur benigne ou maligne. L'activite jonctionnelle indiquait une forte probabilite de benignite, alors qu'un comportement malin etait predit par un index mitotique eleve et une infiltration de la tumeur par des cellules lymphoides.
Zusammenfassung— Es wird ein uberlick uber 43 Falle von kutanen melanozytaren Neoplasien bei Katzen gegeben. Achtundzwanzig der 43 Neoplasmen waren histologisch gutartig, 15 waren bosartig. Das Verhalten der Tumore war unabhangig von der Lokalisation, abgesehen von Tumoren der Augenlider, die stets maligne waren. Histologische Befunde wie epidermale Ulzeration, scharfe Begrenzung der Gewebsrander, Grad der Melanisierung, Tumorzelltyp und Vorhandensein oder Fehlen von Thequen unterschieden die benignen von den malignen Tumoren nicht. Verbindungsaktivitat bedeutete eine hohe Wahrscheinlichkeit fur gutartiges Verhalten, wahrend bosartiges Verhalten durch einen hohen Mitoseindex und Infiltration des Tumors mit lymphoiden Zellen vorhersagbar war.
Resumen En este articulo se analizan cuarenta y tres casos de neoplasia melanocitica cutanea en gatos. Veintiocho de loa cuarenta y tres casos, resultaron canceres benignos histologicamente y quince, malignos. El grado de malignidad no tenia relacion con el sitio de procedencia con la excepcion de que los tumores de parpados que resultaron malignos. Las caracteristicas histologicas de las ulceraciones epidermicas, limpieza de tejidos circundantes, grado de melanizacion, tipo de celula tumoral, y presencia o ausencia de the zeques, no sirvio para la diferenciacion entre maligno y benigno. La actividad de la zona delimitante fue un indicador de alta probabilidad de benignidad, mientras que la el tipo maligno se predijo por un indice mitotico alto e infiltracion del tumor por celulas de tipo linfoide.
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