Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms: New data and a meta-analysis

[1]  J. Fichna,et al.  Current overview of extrinsic and intrinsic factors in etiology and progression of inflammatory bowel diseases , 2014, Pharmacological reports : PR.

[2]  S. Nadifi,et al.  IL23R and ATG16L1 variants in Moroccan patients with inflammatory bowel disease , 2014, BMC Research Notes.

[3]  S. Nadifi,et al.  Methylenetetrahydrofolate reductase C677T variant in Moroccan patients with inflammatory bowel disease. , 2013, Gene.

[4]  L. Zhan,et al.  Analysis of TLR4 and TLR2 polymorphisms in inflammatory bowel disease in a Guangxi Zhuang population. , 2012, World journal of gastroenterology.

[5]  A. Kapsoritakis,et al.  Readressing the Role of Toll-Like Receptor-4 Alleles in Inflammatory Bowel Disease: Colitis, Smoking, and Seroreactivity , 2012, Digestive Diseases and Sciences.

[6]  M. Shalaby,et al.  CARD15/NOD2, CD14 and Toll-like 4 Receptor Gene Polymorphisms in Saudi Patients with Crohn’s Disease , 2012, International journal of molecular sciences.

[7]  S. Jung,et al.  Association Between Toll-Like Receptors/CD14 Gene Polymorphisms and Inflammatory Bowel Disease in Korean Population , 2011, Journal of Korean medical science.

[8]  R. Shi,et al.  [Toll-like receptor gene polymorphisms and susceptibility to inflammatory bowel disease in Chinese Han and Caucasian populations]. , 2010, Zhonghua yi xue za zhi.

[9]  Ruyang Zhang,et al.  The Toll-Like Receptor 4 D299G and T399I Polymorphisms Are Associated with Crohn’s Disease and Ulcerative Colitis: A Meta-Analysis , 2010, Digestion.

[10]  H. Chaabouni,et al.  Tolllike receptor 4 (TLR4) polymorphisms in Tunisian patients with Crohn's disease: genotype-phenotype correlation , 2009, BMC gastroenterology.

[11]  C. Bernstein,et al.  The evolving epidemiology of inflammatory bowel disease , 2009, Current opinion in gastroenterology.

[12]  C. Tamboli,et al.  Advances in epidemiology and diagnosis of inflammatory bowel diseases , 2008, Current gastroenterology reports.

[13]  W. Fries,et al.  Clinical significance of NOD2/CARD15 and Toll-like receptor 4 gene single nucleotide polymorphisms in inflammatory bowel disease. , 2008, World journal of gastroenterology.

[14]  L. Griffiths,et al.  Novel NOD2 haplotype strengthens the association between TLR4 Asp299gly and Crohn's disease in an Australian population , 2008, Inflammatory bowel diseases.

[15]  M. Netea,et al.  Functional Consequences of Toll-like Receptor 4 Polymorphisms , 2008, Molecular medicine.

[16]  P. Rossmann,et al.  Expression of Toll-like Receptor 2 (TLR2), TLR4, and CD14 in Biopsy Samples of Patients With Inflammatory Bowel Diseases: Upregulated Expression of TLR2 in Terminal Ileum of Patients With Ulcerative Colitis , 2008, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[17]  G. Veres,et al.  Increased expression of Toll‐like receptor (TLR) 2 and TLR4 in the colonic mucosa of children with inflammatory bowel disease , 2007, Clinical and experimental immunology.

[18]  F. Nagy,et al.  The c.1-260C>T Promoter Variant of CD14 but Not the c.896A>G (p.D299G) Variant of Toll-Like Receptor 4 (TLR4) Genes Is Associated with Inflammatory Bowel Disease , 2007, Digestion.

[19]  A. Shelling,et al.  Has Toll-Like Receptor 4 Been Prematurely Dismissed as an Inflammatory Bowel Disease Gene? Association Study Combined With Meta-Analysis Shows Strong Evidence for Association , 2007, The American Journal of Gastroenterology.

[20]  T. Merriman,et al.  TLR2, TLR4 and TLR9 polymorphisms and Crohn's disease in a New Zealand Caucasian cohort , 2007, Journal of gastroenterology and hepatology.

[21]  D. Hommes,et al.  Genetic susceptibility has a more important role in pediatric‐onset Crohn's disease than in adult‐onset Crohn's disease , 2007, Inflammatory bowel diseases.

[22]  M. Daly,et al.  The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases , 2007, Genes and Immunity.

[23]  C. O'Morain,et al.  The prevalence of genetic and serologic markers in an unselected European population‐based cohort of IBD patients , 2007, Inflammatory bowel diseases.

[24]  S. Akira,et al.  Toll-like receptors and innate immunity , 2006, Journal of Molecular Medicine.

[25]  Alexis Peralta,et al.  NOD2/CARD15 and Toll-like 4 receptor gene polymorphism in Chilean patients with inflammatory bowel disease. , 2006, European cytokine network.

[26]  H. S. Warren,et al.  Toll-like receptors. , 2005, Critical care medicine.

[27]  M. Cottone,et al.  Intestinal Permeability and Genetic Determinants in Patients, First-Degree Relatives, and Controls in a High-Incidence Area of Crohn's Disease in Southern Italy , 2005, The American Journal of Gastroenterology.

[28]  J. Satsangi,et al.  Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. , 2005, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

[29]  A. Peña,et al.  Polymorphisms of CD14 gene and TLR4 gene are not associated with ulcerative colitis in Chinese patients , 2005, Postgraduate Medical Journal.

[30]  D. Hommes,et al.  Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn’s disease patients , 2005, Journal of Molecular Medicine.

[31]  A. Crispin,et al.  The Role of Toll‐like Receptor 4 Asp299Gly and Thr399Ile Polymorphisms and CARD15/NOD2 Mutations in the Susceptibility and Phenotype of Crohn's Disease , 2005, Inflammatory bowel diseases.

[32]  G. T. te Meerman,et al.  Association Between Toll‐like Receptor 4 and Inflammatory Bowel Disease , 2005, Inflammatory bowel diseases.

[33]  T. Molnár,et al.  Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations. , 2005, World journal of gastroenterology.

[34]  P. Felsburg,et al.  Toll-like receptor-mediated responses of primary intestinal epithelial cells during the development of colitis. , 2005, American journal of physiology. Gastrointestinal and liver physiology.

[35]  J. Crusius,et al.  The toll-like receptor 4 (TLR4) Asp299Gly polymorphism is associated with colonic localisation of Crohn’s disease without a major role for the Saccharomyces cerevisiae mannan-LBP-CD14-TLR4 pathway , 2005, Gut.

[36]  M. Gazouli,et al.  Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population. , 2005, World journal of gastroenterology.

[37]  LaszloLakatos,et al.  Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: Phenotype-genotype correlations , 2005 .

[38]  T. Mussack,et al.  Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis. , 2004, Clinical immunology.

[39]  H. Drummond,et al.  NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe? , 2004, Genes and Immunity.

[40]  K. Van Steen,et al.  Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn’s disease and ulcerative colitis , 2004, Gut.

[41]  D. Podolsky,et al.  Mechanisms of cross hyporesponsiveness to Toll-like receptor bacterial ligands in intestinal epithelial cells. , 2004, Gastroenterology.

[42]  D. Hommes,et al.  A functional single nucleotide polymorphism of the Tlr4 gene is correlated with Crohn's disease but not with ulcerative colitis , 2003 .

[43]  G. Rogler,et al.  Toll-like receptors 2 and 4 are up-regulated during intestinal inflammation. , 2001, Gastroenterology.

[44]  M. Oka,et al.  Simple genotype analysis of the Asp299Gly polymorphism of the Toll‐like receptor‐4 gene that is associated with lipopolysaccharide hyporesponsiveness , 2002, Journal of clinical laboratory analysis.

[45]  Ruslan Medzhitov,et al.  Toll-like receptors and innate immunity , 2001, Nature Reviews Immunology.

[46]  Dirk E. Smith,et al.  Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction , 2001, Nature.

[47]  M. Abreu,et al.  Decreased Expression of Toll-Like Receptor-4 and MD-2 Correlates with Intestinal Epithelial Cell Protection Against Dysregulated Proinflammatory Gene Expression in Response to Bacterial Lipopolysaccharide1 , 2001, The Journal of Immunology.

[48]  S. Akira,et al.  Toll-like receptors: critical proteins linking innate and acquired immunity , 2001, Nature Immunology.

[49]  D. Podolsky,et al.  Differential Alteration in Intestinal Epithelial Cell Expression of Toll-Like Receptor 3 (TLR3) and TLR4 in Inflammatory Bowel Disease , 2000, Infection and Immunity.

[50]  D. Schwartz,et al.  TLR4 mutations are associated with endotoxin hyporesponsiveness in humans , 2000, Nature Genetics.

[51]  F. Gusovsky,et al.  Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction* , 1999, The Journal of Biological Chemistry.

[52]  G. Hardiman,et al.  A family of human receptors structurally related to Drosophila Toll. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[53]  C. Janeway,et al.  A human homologue of the Drosophila Toll protein signals activation of adaptive immunity , 1997, Nature.