DEVELOPMENT OF PURULENT MENINGITIS IN A CHILD WITH NEPHROTIC SYNDROME WHILE RECEIVING CEPHTRIAXONE PLUS AMIKACIN

A child with nephrotic syndrome (NS) presented with peritonitis caused by E. coli susceptible to both cephtriaxone and amikacin. Purulent meningitis developed in accompanying with clinical and laboratory findings at the 5th day of treatment. Pneumococcal antigen was detected in cerebro-spinal fluid and meningitis was treated with meropenem. Development of pneumococal meningitis while receiving broad-spectrum antibiotics for peritonitis is an unusual situation.