The relationship between normal lung sounds, age, and gender.

Auscultation is one of the most important noninvasive and feasible methods for the detection of lung diseases. Systematic changes in breathing sounds with increasing age are of diagnostic importance. To investigate these changes, we recorded lung sounds taken from four locations in the posterior thorax of 162 subjects, together with airflow. The data were analyzed according to age, sex, and smoking habit. In order to describe the power spectrum of the lung sounds, we calculated mean and median frequency, frequency with the highest power, and a ratio (Q) of relative power of the two frequency bands of 330 to 600 Hz and 60 to 330 Hz. Linear regression analysis was used as a measurement of age-dependence of these variables. Significant differences in Q were found in men versus women (p < 0.05), but not in smokers versus nonsmokers. Within the groups, a small but significant correlation existed between Q and age (r(2) </= 0.1, p < 0.05). For both men and women, a slight increase of the relative power in the frequency band of 330 to 600 Hz was recorded with increasing age. However, on the basis of large individual variations, these small changes (DeltaQ approximately 5%, SD(Q) >/= +/- 5%) have no clinical significance and need not to be considered in the automatic detection of lung diseases by analyzing lung sounds.

[1]  X Q Sun,et al.  Estimation of analogue pre-filtering characteristics for CORSA standardisation. , 1998, Technology and health care : official journal of the European Society for Engineering and Medicine.

[2]  H. Pasterkamp,et al.  Respiratory sounds. Advances beyond the stethoscope. , 1997, American journal of respiratory and critical care medicine.

[3]  T. Penzel,et al.  Digital recording and computer-based analysis of lung sounds , 1996, Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[4]  H. Pasterkamp,et al.  Lung sound spectra at standardized air flow in normal infants, children, and adults. , 1996, American journal of respiratory and critical care medicine.

[5]  P Piirilä,et al.  Averaged and time-gated spectral analysis of respiratory sounds. Repeatability of spectral parameters in healthy men and in patients with fibrosing alveolitis. , 1996, Chest.

[6]  N Gavriely,et al.  Airflow effects on amplitude and spectral content of normal breath sounds. , 1996, Journal of applied physiology.

[7]  M Nissan,et al.  Spectral characteristics of chest wall breath sounds in normal subjects. , 1995, Thorax.

[8]  G R Wodicka,et al.  Measurement of respiratory acoustic signals. Effect of microphone air cavity width, shape, and venting. , 1995, Chest.

[9]  G R Wodicka,et al.  Measurement of respiratory acoustic signals. Effect of microphone air cavity depth. , 1994, Chest.

[10]  N Gavriely,et al.  Repeatability of measurements of normal lung sounds. , 1994, American journal of respiratory and critical care medicine.

[11]  H. Pasterkamp,et al.  Measurement of respiratory acoustical signals. Comparison of sensors. , 1993, Chest.

[12]  H. Pasterkamp,et al.  Tracheal sound spectra depend on body height. , 1993, The American review of respiratory disease.

[13]  J Vanderschoot,et al.  Lung sound intensity in patients with emphysema and in normal subjects at standardised airflows. , 1992, Thorax.

[14]  P. Escourrou,et al.  Intraction between tracheal sound and flow rate: a comparison of some different flow evaluations from lung sounds , 1990, IEEE Transactions on Biomedical Engineering.

[15]  H. Pasterkamp,et al.  Digital respirosonography. New images of lung sounds. , 1989, Chest.

[16]  Y Ploysongsang,et al.  Airflow and normal lung sounds. , 1988, The American review of respiratory disease.

[17]  M. Ono,et al.  Relationship between forced expiratory flow and tracheal sounds. Possible effect of vortices on flow. , 1988, Respiration; international review of thoracic diseases.

[18]  D. Cugell,et al.  International Symposium on Lung Sounds. Synopsis of proceedings. , 1987, Chest.

[19]  S. Kraman,et al.  Effects of lung volume and airflow on the frequency spectrum of vesicular lung sounds. , 1986, Respiration physiology.

[20]  H J Colebatch,et al.  A longitudinal study of pulmonary distensibility in healthy adults. , 1986, Respiration physiology.

[21]  S. Kraman,et al.  The relationship between airflow and lung sound amplitude in normal subjects. , 1984, Chest.

[22]  J. Racineux,et al.  An accurate recording system and its use in breath sounds spectral analysis. , 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

[23]  S. Kraman,et al.  Comparison of lung sound and transmitted sound amplitude in normal men. , 1983, The American review of respiratory disease.

[24]  R. Loudon The lung speaks out. , 1982, The American review of respiratory disease.

[25]  R. Murphy,et al.  Auscultation of the lung: past lessons, future possibilities. , 1981, Thorax.

[26]  N Gavriely,et al.  Spectral characteristics of normal breath sounds. , 1981, Journal of applied physiology: respiratory, environmental and exercise physiology.

[27]  W. Knowler,et al.  Visual lung-sound characterization by time-expanded wave-form analysis. , 1977, The New England journal of medicine.

[28]  R. Bégin,et al.  Flow and age dependence of airway closure and dynamic compliance. , 1975, Journal of applied physiology.

[29]  R L Murphy,et al.  Chest auscultation in the diagnosis of pulmonary asbestosis. , 1973, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[30]  J. Mead,et al.  Elasticity of human lungs in relation to age. , 1968, Journal of applied physiology.