Emerging & re-emerging infections in India: An overview

The incidence of emerging infectious diseases in humans has increased within the recent past or threatens to increase in the near future. Over 30 new infectious agents have been detected worldwide in the last three decades; 60 per cent of these are of zoonotic origin. Developing countries such as India suffer disproportionately from the burden of infectious diseases given the confluence of existing environmental, socio-economic, and demographic factors. In the recent past, India has seen outbreaks of eight organisms of emerging and re-emerging diseases in various parts of the country, six of these are of zoonotic origin. Prevention and control of emerging infectious diseases will increasingly require the application of sophisticated epidemiologic and molecular biologic technologies, changes in human behaviour, a national policy on early detection of and rapid response to emerging infections and a plan of action. WHO has made several recommendations for national response mechanisms. Many of these are in various stages of implementation in India. However, for a country of size and population of India, the emerging infections remain a real and present danger. A meaningful response must approach the problem at the systems level. A comprehensive national strategy on infectious diseases cutting across all relevant sectors with emphasis on strengthened surveillance, rapid response, partnership building and research to guide public policy is needed.

[1]  N. Tankhiwale,et al.  Re-emergence of Vibrio cholerae O139 serogroup during 1998 in Nagpur (Maharashtra), India. , 1999, The Indian journal of medical research.

[2]  J. Thakur,et al.  Epidemiological features of pneumonic plague outbreak in Himachal Pradesh, India. , 2009, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[3]  T. Mahanta,et al.  Investigation of an Outbreak of Diphtheria in Borborooah Block of Dibrugarh District, Assam , 2010, Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine.

[4]  J. Bresee,et al.  Nipah Virus Encephalitis Reemergence, Bangladesh , 2004, Emerging infectious diseases.

[5]  C. Bridges,et al.  Case-control study of risk factors for avian influenza A (H5N1) disease, Hong Kong, 1997. , 1999, The Journal of infectious diseases.

[6]  Lalit Kant,et al.  Combating emerging infectious diseases in India: Orchestrating a symphony , 2008, Journal of Biosciences.

[7]  V. Arankalle,et al.  An outbreak of Chandipura virus encephalitis in the eastern districts of Gujarat state, India. , 2005, The American journal of tropical medicine and hygiene.

[8]  H. Hoogstraal The epidemiology of tick-borne Crimean-Congo hemorrhagic fever in Asia, Europe, and Africa. , 1979, Journal of medical entomology.

[9]  Y. Takeda,et al.  Resurgence of Vibrio cholerae O139 Bengal with altered antibiogram in Calcutta, India , 1996, The Lancet.

[10]  Plague: a decade since the 1994 outbreaks in India. , 2005, The Journal of the Association of Physicians of India.

[11]  Stephen P. Luby,et al.  Foodborne Transmission of Nipah Virus, Bangladesh , 2006, Emerging infectious diseases.

[12]  R. Joshi,et al.  Chikungunya epidemic: an Indian perspective. , 2006, The National medical journal of India.

[13]  M. Lal,et al.  Reappearance of Vibrio cholerae O139 during March-August, 1998 in Ludhiana (Punjab), India. , 1999, The Indian journal of medical research.

[14]  M. Peiris,et al.  International Health Regulations (2005) , 2005, The Lancet.

[15]  Chris A Whitehouse,et al.  Crimean-Congo hemorrhagic fever. , 2004, Antiviral research.

[16]  J. L. Montagne,et al.  Emerging infectious diseases. , 1994, The Journal of infectious diseases.

[17]  G. Agrawal,et al.  Emergence and re-emergence of Vibrio cholerae 0139: an epidemiological study during 1993-2002 at Nagpur, Central India. , 2003, Indian journal of medical sciences.

[18]  R. Lodha,et al.  Diphtheria in urban slums in north India , 2000, The Lancet.

[19]  H EmadiKoochak,et al.  Crimean-Congo Hemorrhagic Fever , 2003 .

[20]  O. Ergonul,et al.  Crimean-Congo haemorrhagic fever , 2006 .

[21]  S. B. Pole,et al.  Plague dynamics are driven by climate variation , 2006, Proceedings of the National Academy of Sciences.

[22]  K. S. Gill,et al.  Nipah/Hendra virus outbreak in Siliguri, West Bengal, India in 2001. , 2006, The Indian journal of medical research.

[23]  S. Yamasaki,et al.  Vibrio cholerae O139 Bengal: odyssey of a fortuitous variant. , 2003, Microbes and infection.

[24]  I. Saha,et al.  A report of diphtheria surveillance from a rural medical college hospital. , 1998, Journal of the Indian Medical Association.

[25]  K. Gage,et al.  Incidence of plague associated with increased winter-spring precipitation in New Mexico. , 1999, The American journal of tropical medicine and hygiene.

[26]  J. Shastri,et al.  Resurgence of diphtheria in the vaccination era. , 2007, Indian journal of medical microbiology.

[27]  J. Peiris,et al.  Re-emergence of fatal human influenza A subtype H5N1 disease , 2004, The Lancet.

[28]  Mark E.J. Woolhouse,et al.  Host Range and Emerging and Reemerging Pathogens , 2005, Emerging infectious diseases.

[29]  M. Murhekar,et al.  Persistence of Diphtheria in India , 2011, Indian Journal of Community Medicine.

[30]  A. Fauci,et al.  Infectious diseases: considerations for the 21st century. , 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[31]  V. Mittal,et al.  Quick control of bubonic plague outbreak in Uttar Kashi, India. , 2004, The Journal of communicable diseases.

[32]  N. Wairagkar,et al.  BrainStem Encephalitis Associated with Chandipura in Andhra Pradesh Outbreak , 2007, Journal of tropical pediatrics.

[33]  K. Ingole,et al.  Re-emergence of Vibrio cholerae serogroup O139 during June-August, 1997 in Yavatmal (Maharashtra). , 1998, The Indian journal of medical research.

[34]  C. Whitehouse,et al.  Crimean-Congo hemorrhagic fever virus. , 2005, Current molecular medicine.

[35]  S. Zodpey,et al.  Public Health Education in India: Need and Demand Paradox , 2011, Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine.

[36]  D. Marchant,et al.  Risk factors. , 1994, Obstetrics and gynecology clinics of North America.

[37]  V. Arankalle,et al.  Chandipura virus encephalitis outbreak among children in Nagpur division, Maharashtra, 2007. , 2010, The Indian journal of medical research.

[38]  M E Woolhouse,et al.  Risk factors for human disease emergence. , 2001, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[39]  Amit Pal,et al.  Emergence of novel strain of Vibrio cholerae with epidemic potential in southern and eastern India , 1993, The Lancet.

[40]  P. Bhatt,et al.  Chandipura: a new Arbovirus isolated in India from patients with febrile illness. , 1967, The Indian journal of medical research.

[41]  M. Schleiss,et al.  Pandemic Influenza A (H1N1) , 2009, Pediatric Research.

[42]  Tirthankar Roy,et al.  National Family Health Survey (NFHS-2) 1998-99. India. , 2000 .

[43]  K. Krishnamoorthy,et al.  Burden of chikungunya in India: estimates of disability adjusted life years (DALY) lost in 2006 epidemic. , 2009, Journal of vector borne diseases.