Elective neck dissection in early‐stage oral squamous cell carcinoma—does it influence recurrence and survival?

This study investigates the influence on survival and regional control rates of neck dissection therapy at the time of surgery of the primary tumor in early stages of squamous cell carcinoma (SCC) of the oral cavity.

[1]  J. Shah,et al.  Changing concepts in the surgical management of the cervical node metastasis. , 2003, Oral oncology.

[2]  E. Strong,et al.  Predictive value of tumor thickness in squamous carcinoma confined to the tongue and floor of the mouth. , 1986, American journal of surgery.

[3]  D. Godden,et al.  Recurrent neck disease in oral cancer. , 2002, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[4]  N H Terry,et al.  Can we detect or predict the presence of occult nodal metastases in patients with squamous carcinoma of the oral tongue? , 1998, Head & neck.

[5]  J. Attie,et al.  Elective radical neck dissection in epidermoid cancer of the head and neck. A retrospective analysis of 853 cases of mouth, pharynx, and larynx cancer , 1991, Cancer.

[6]  A. Yuen,et al.  Elective neck dissection versus observation in the treatment of early oral tongue carcinoma , 1997, Head & neck.

[7]  R. Ferris,et al.  Elective Neck Dissection and Survival in Patients With Squamous Cell Carcinoma of the Oral Cavity and Oropharynx , 2004, The Laryngoscope.

[8]  T. Ogawa,et al.  Prognostic significance of late cervical metastasis and distant failure in patients with stage I and II oral tongue cancers. , 2005, Oral oncology.

[9]  G. Snow,et al.  Is selective neck dissection really as efficacious as modified radical neck dissection for elective treatment of the clinically negative neck in patients with squamous cell carcinoma of the upper respiratory and digestive tracts? , 1998, Archives of otolaryngology--head & neck surgery.

[10]  Luiz Paulo Kowalski,et al.  Predictive factors of occult metastasis and prognosis of clinical stages I and II squamous cell carcinoma of the tongue and floor of the mouth. , 2004, Oral oncology.

[11]  S. Hao,et al.  The role of supraomohyoid neck dissection in patients of oral cavity carcinoma. , 2002, Oral oncology.

[12]  T. Hadar,et al.  Squamous cell carcinoma of the oral tongue. , 1991, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[13]  J. Woolgar,et al.  Prediction of cervical lymph node metastasis in squamous cell carcinoma of the tongue/floor of mouth , 1995, Head & neck.

[14]  A. Eckardt,et al.  Neck dissection in oral cancer--clinical review and analysis of prognostic factors. , 2002, International journal of oral and maxillofacial surgery.

[15]  W. Tilakaratne,et al.  Leiomyosarcoma of the oral cavity: Report of seven cases and review of literature , 2006 .

[16]  L. Sennaroğlu,et al.  The value of elective neck dissection in treatment of cancer of the tongue. , 2001, American journal of otolaryngology.

[17]  D. Soutar,et al.  Improved survival for patients with clinically T1/T2, N0 tongue tumors undergoing a prophylactic neck dissection , 1999, Head & neck.

[18]  William A. Maddox,et al.  Vicissitudes of head and neck cancer , 1984 .

[19]  R. Spiro,et al.  Improved survival in the treatment of squamous carcinoma of the oral tongue. , 1993, American journal of surgery.

[20]  K. Lam,et al.  Occult lymph node metastasis in small oral tongue cancers , 1992, Head & neck.

[21]  J. Teichgraeber,et al.  The incidence of occult metastases for cancer of the oral tongue and floor of the mouth: treatment rationale. , 1984, Head & neck surgery.

[22]  M. Quintanilla,et al.  Prognostic significance of intratumoral lymphangiogenesis in squamous cell carcinoma of the oral cavity , 2004, Cancer.

[23]  Roberto A. Lima,et al.  Elective Neck Dissection versus Observation in Stage I Squamous Cell Carcinomas of the Tongue and Floor of the Mouth , 2001, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[24]  J. Batsakis,et al.  Microscopic cut-through of cancer in the surgical treatment of squamous carcinoma of the tongue. Prognostic and therapeutic implications. , 1986, American journal of surgery.

[25]  R. Lima,et al.  Supraomohyoid neck dissection in the treatment of T1/T2 squamous cell carcinoma of oral cavity. , 1994, American journal of surgery.

[26]  G. Snow,et al.  The Incidence of Micrometastases in Neck Dissection Specimens Obtained From Elective Neck Dissections , 1996, The Laryngoscope.

[27]  R. Reddick,et al.  Prognostic factors in the recurrence of stage I and II squamous cell cancer of the oral cavity. , 1992, Archives of otolaryngology--head & neck surgery.

[28]  Yoshihiro Yamashita,et al.  Risk factors for late cervical lymph node metastases in patients with stage I or II carcinoma of the tongue , 2002, Head & neck.

[29]  Petra Ambrosch,et al.  Elective and therapeutic selective neck dissection. , 2006, Oral oncology.

[30]  C. Silver,et al.  Computed tomography of the clinically negative neck , 1990 .

[31]  H. Tideman.  Elective radical neck dissection in epidermoid cancer of the head and neck. A retrospective analysis of 853 cases of mouth, pharynx, and larynx cancer , 1991 .

[32]  N. Breach,et al.  Management of the N0 neck in early cancer of the oral tongue. , 1999, Clinical otolaryngology and allied sciences.

[33]  C. Silver,et al.  Computed tomography of the clinically negative neck , 1990, Head & neck.

[34]  G. Weinstein,et al.  Multivariate Predictors of Occult Neck Metastasis in Early Oral Tongue Cancer , 2003, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[35]  C. Fisher,et al.  Tumour thickness predicts cervical nodal metastases and survival in early oral tongue cancer. , 2003, Oral oncology.