Association between Love Breakup and Suicidal Ideation in Peruvian Medical Students: A Cross-Sectional Study during the COVID-19 Pandemic

Abstract Objective: We aimed to determine the association between a major romantic breakup and suicidal ideation in medical students from three universities in Peru. Methods: A cross-sectional study was conducted during the first pandemic wave in 2021 on medical students from three universities in northern Peru. The outcome was suicidal ideation, measured with question nine of the PHQ-9. The exposure was the experience of a major love breakup during the pandemic. In addition, its association with other covariates (age, sex, family members infected with COVID-19, deceased family members with COVID-19, insomnia, and anxiety, among others) was examined. Results and discussions: Out of 370 students, 19.5% reported a major love breakup during the pandemic (95%CI: 15.5–23.8), and 34.3% had suicidal ideation (95%CI: 29.4–39.4). Having a major love breakup was associated with a higher prevalence of suicidal ideation (PR: 1.49, 95%CI: 1.32–1.67). Moderate insomnia (PR: 2.56, 95%CI: 1.70–3.87) and anxiety symptoms (PR: 1.94, 1.10–3.44) were also associated with suicidal ideation. Conclusion: Our study provides evidence of a significant association between a major love breakup and suicidal ideation. This finding emphasizes the need for further research to better understand this association and inform the development of effective suicide prevention policies in medical education.

[1]  N. Davies,et al.  Factors Associated with SARS-CoV-2 Positivity in Patients Treated at the Lambayeque Regional Hospital, Peru during a Pandemic Period , 2022, Sustainability.

[2]  Mario J. Valladares-Garrido,et al.  Factors Associated with Anxiety, Depression, and Stress in Peruvian University Students during the COVID-19 Pandemic , 2022, International journal of environmental research and public health.

[3]  C. Mejía,et al.  A cross-sectional study to assess the level of satisfaction with virtual education in Peruvian medical students , 2022, Frontiers in Public Health.

[4]  Mario J. Valladares-Garrido,et al.  Suicide Risk in Military Personnel during the COVID-19 Health Emergency in a Peruvian Region: A Cross-Sectional Study , 2022, International journal of environmental research and public health.

[5]  Mario J. Valladares-Garrido,et al.  Prevalence and Associated Factors of Depression, Anxiety, and Stress in University Students in Paraguay during the COVID-19 Pandemic , 2022, International journal of environmental research and public health.

[6]  Mario J. Valladares-Garrido,et al.  Association between Working Time and Burnout Syndrome in Peruvian Military during the Second Epidemic Wave of COVID-19 , 2022, International journal of environmental research and public health.

[7]  Xinlu Wang,et al.  Suicide resilience: A concept analysis , 2022, Frontiers in Psychiatry.

[8]  Mario J. Valladares-Garrido,et al.  Smartphone overuse, depression & anxiety in medical students during the COVID-19 pandemic , 2022, PloS one.

[9]  C. Díaz-Vélez,et al.  [Prevalence and factors associated with eating disorders in Peruvian Human Medicine students in the context of the COVID-19 pandemic: a multicentre study]. , 2022, Revista colombiana de psiquiatria.

[10]  Mario J. Valladares-Garrido,et al.  Association between Family Dysfunction and Post-Traumatic Stress Disorder in School Students during the Second COVID-19 Epidemic Wave in Peru , 2022, International journal of environmental research and public health.

[11]  Mario J. Valladares-Garrido,et al.  Clinical-epidemiologic variation in patients treated in the first and second wave of COVID-19 in Lambayeque, Peru: A cluster analysis , 2022, International Journal of Infectious Diseases.

[12]  Mario J. Valladares-Garrido,et al.  Prevalence and Factors Associated with Insomnia in Military Personnel: A Retrospective Study during the Second COVID-19 Epidemic Wave in Peru , 2022, Healthcare.

[13]  T. Fujiwara,et al.  Association between Frequency of Conversations and Suicidal Ideation among Medical Students during COVID-19 Pandemic in Japan , 2022, International journal of environmental research and public health.

[14]  T. Niederkrotenthaler,et al.  Romantic Relationships and Mental Health During the COVID-19 Pandemic in Austria: A Population-Based Cross-Sectional Survey , 2022, Frontiers in Psychology.

[15]  W. Pickett,et al.  The Impact of the COVID-19 Pandemic on the Mental Health of First-Year Undergraduate Students Studying at a Major Canadian University: A Successive Cohort Study , 2022, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[16]  M. Mamun,et al.  Prevalence and Factors Associated With Depression and Suicidal Ideation During the COVID-19 Pandemic Among University Students in Uganda: A Cross-Sectional Study , 2022, Frontiers in Psychiatry.

[17]  W. Sun,et al.  Associations between academic burnout, resilience and life satisfaction among medical students: a three-wave longitudinal study , 2022, BMC medical education.

[18]  Mario J. Valladares-Garrido,et al.  Self-medication in hospitalized patients with COVID-19: A cross-sectional study in northern Peru. , 2022, Germs.

[19]  Diego Crisol-Deza,et al.  Factors associated with suicidal ideation among medical students during the initial phase of the COVID-19 pandemic in Peru: A multicenter study , 2022, Death studies.

[20]  A. Amstadter,et al.  The COVID-19 pandemic impacts psychiatric outcomes and alcohol use among college students , 2022, European journal of psychotraumatology.

[21]  A. Domı́nguez-González,et al.  Depression and suicidal ideation in Mexican medical students during COVID-19 outbreak. A longitudinal study , 2022, Heliyon.

[22]  K. Fournier,et al.  Risk factors for suicidal ideation and suicide attempt among medical students: A meta-analysis , 2021, PloS one.

[23]  Virgilio E. Failoc-Rojas,et al.  Indice desarrollo humano y la tasa de letalidad por Covid-19: Estudio ecológico en América , 2021, Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo.

[24]  P. Berthelot,et al.  Factors Associated with Psychological Distress in French Medical Students during the COVID-19 Health Crisis: A Cross-Sectional Study , 2021, International journal of environmental research and public health.

[25]  Virgilio E. Failoc-Rojas,et al.  Factores asociados a seropositividad para SARS-CoV-2 en pacientes atendidos en un hospital de zona altoandina peruana , 2021, Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo.

[26]  Mario J. Valladares-Garrido,et al.  [Mortality in patients hospitalized with COVID-19 in northern Peru]. , 2021, Revista medica de Chile.

[27]  Dian Kristiani Irawaty,et al.  Family Resilience during COVID-19 Pandemic: A Literature Review , 2021, Family journal.

[28]  Ping Wu,et al.  Prevalence and Risk Factors of Mental Health Symptoms and Suicidal Behavior Among University Students in Wuhan, China During the COVID-19 Pandemic , 2021, Frontiers in Psychiatry.

[29]  D. O'Connor,et al.  Mental health and well-being during the COVID-19 pandemic: longitudinal analyses of adults in the UK COVID-19 Mental Health & Wellbeing study , 2020, The British Journal of Psychiatry.

[30]  M. Abumadini,et al.  Suicidal Ideation Among Medical Students in Dammam, Saudi Arabia. , 2020, Crisis.

[31]  Tania Rodríguez Salazar,et al.  Intimidad y relaciones de pareja durante la pandemia de la COVID-19 en Guadalajara , 2020 .

[32]  J. Gehrels,et al.  Onset insomnia and insufficient sleep duration are associated with suicide ideation in university students and athletes. , 2020, Journal of affective disorders.

[33]  Henock Asfaw,et al.  Prevalence and associated factors of suicidal ideation and attempt among undergraduate medical students of Haramaya University, Ethiopia. A cross sectional study , 2020, PloS one.

[34]  D. Gunnell,et al.  Suicide Deaths in University Students in a UK City Between 2010 and 2018 - Case Series. , 2020, Crisis.

[35]  M. Gray,et al.  Mental health and relationships during the COVID-19 pandemic , 2020 .

[36]  Darla Still Romantic Relationship Quality and Suicidal Ideation in Young Adulthood , 2020 .

[37]  G. Onder,et al.  Clinical Characteristics of Hospitalized Individuals Dying with COVID-19 by Age Group in Italy , 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

[38]  M. Khosravi,et al.  The relationship between neuroticism and suicidal thoughts among medical students: Moderating role of attachment styles , 2020, Journal of family medicine and primary care.

[39]  Kamila R. Irvine,et al.  Prevalence and psychiatric correlates of suicidal ideation in UK university students. , 2020, Journal of affective disorders.

[40]  Melissa Noemí Paredes Torres,et al.  Perfil clínico de personalidad mediante el Inventario Clínico Multiaxial (MCMI-II) en población ludópata del Instituto Nacional de Salud Mental Honorio Delgado – Hideyo Noguchi , 2019 .

[41]  B. Martínez,et al.  Comprender el suicidio desde una perspectiva de género: una revisión crítica bibliográfica , 2019 .

[42]  David P. Nalbone,et al.  Suicidal Risk Following the Termination of Romantic Relationships , 2018, Crisis.

[43]  Cinthia Cruz del Castillo,et al.  Characterization of a breakup in couples of university students: Differences in cognitive assessment of the event , 2018 .

[44]  Jorge Luis Salinas Rodríguez,et al.  Incidencia del duelo en la ruptura amorosa en estudiantes universitarios en un Centro de Crisis, Emergencias y Atención al Suicidio (CREAS) , 2018 .

[45]  María Esther Barradas Alarcón,et al.  Prevalencia de la ideación suicida en estudiantes de Medicina en Latinoamérica:: un meta análisis , 2017 .

[46]  Zubia Veqar,et al.  Validity and reliability of insomnia severity index and its correlation with pittsburgh sleep quality index in poor sleepers among Indian university students , 2017, International journal of adolescent medicine and health.

[47]  P. Batterham,et al.  The impact of intimate partner relationships on suicidal thoughts and behaviours: A systematic review. , 2016, Journal of affective disorders.

[48]  A. Zaslavsky,et al.  Diagnostic Validity of the Generalized Anxiety Disorder - 7 (GAD-7) among Pregnant Women , 2015, PloS one.

[49]  L. Rampal,et al.  Prevalence and predictors of suicidality among medical students in a public university. , 2015, The Medical journal of Malaysia.

[50]  R. Menezes,et al.  Suicidal ideation among medical students of Pakistan: a cross-sectional study. , 2014, Journal of forensic and legal medicine.

[51]  H. Christensen,et al.  Temporal effects of separation on suicidal thoughts and behaviours. , 2014, Social science & medicine.

[52]  A. Perales,et al.  Conducta suicida en estudiantes de la escuela de nutrición de una universidad pública peruana. Suicidal behavior in students of a School of Nutrition at a public Peruvian University. , 2014 .

[53]  K. Kasai,et al.  Psychosocial factors associated with suicidal ideation in clinical patients with depression. , 2013, Journal of affective disorders.

[54]  W. McCall,et al.  The Link Between Suicide and Insomnia: Theoretical Mechanisms , 2013, Current Psychiatry Reports.

[55]  Manuel André Virú-Loza,et al.  Factores asociados a planeamiento suicida en estudiantes de una Escuela de Nutrición en Lima, Perú, 2009 , 2013 .

[56]  J. Pirkis,et al.  Factors associated with suicidal thoughts in a large community study of older adults , 2012, British Journal of Psychiatry.

[57]  F. León-Jiménez,et al.  Tamizaje de salud mental mediante el test MINI en estudiantes de Medicina , 2012 .

[58]  E. Bixler,et al.  The Spanish version of the Insomnia Severity Index: a confirmatory factor analysis. , 2012, Sleep medicine.

[59]  C. Morin,et al.  The Insomnia Severity Index: psychometric indicators to detect insomnia cases and evaluate treatment response. , 2011, Sleep.

[60]  T. Schwenk,et al.  Depression, stigma, and suicidal ideation in medical students. , 2010, JAMA.

[61]  Yueqin Huang,et al.  [Study on the factors influencing suicidal ideation among medical students in Beijing]. , 2008, Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi.

[62]  T. Joiner,et al.  Sleep disturbances and suicide risk: A review of the literature , 2007, Neuropsychiatric disease and treatment.

[63]  B. Löwe,et al.  A brief measure for assessing generalized anxiety disorder: the GAD-7. , 2006, Archives of internal medicine.

[64]  Ricardo Sánchez Pedraza,et al.  Estudio de la imitación como factor de riesgo para ideación suicida en estudiantes universitarios adolescentes , 2005 .

[65]  S. Luthar,et al.  The construct of resilience: Implications for interventions and social policies , 2000, Development and Psychopathology.

[66]  R. Kessler,et al.  Prevalence of and risk factors for lifetime suicide attempts in the National Comorbidity Survey. , 1999, Archives of general psychiatry.

[67]  M. Bonnet,et al.  24-Hour metabolic rate in insomniacs and matched normal sleepers. , 1995, Sleep.

[68]  P. Leombruni,et al.  Suicidal ideation among Italian medical students: prevalence and associated factors from a multicenter study. , 2021, Annali dell'Istituto superiore di sanita.

[69]  C. Mejía,et al.  Male Chauvinism Among Peruvian Medical Students: Related Socio-Educational Factors in 12 Peruvian Universities. , 2019 .

[70]  Dominique Kazan The Impact of Relationship Separation on Suicidality and Mental Health , 2018 .

[71]  T. Niederkrotenthaler,et al.  Relationship Satisfaction and Risk Factors for Suicide , 2017, Crisis.

[72]  C. Castillo,et al.  Ruptura de la pareja en jóvenes: factores relacionados con su impacto , 2017 .

[73]  É. Susánszky,et al.  [Sleep disturbances and nightmares as risk factors for suicidal behavior among men and women]. , 2011, Psychiatria Hungarica : A Magyar Pszichiatriai Tarsasag tudomanyos folyoirata.

[74]  R. Huertas Revista de la Asociación Española de Neuropsiquiatría , 2003 .