COMPARISON OF ENDOMETRIAL TISSUE SAMPLE BY MANUAL VACUUM ASPIRATION VERSUS DILATION & CURETTAGE IN FEMALES PRESENTING WITH ABNORMAL UTERINE BLEEDING

Abnormal uterine bleeding (AUB) is bleeding from uterine corpus , abnormal in volume, regularity, or timing. Objective: To compare the efficacy in terms of adequate endometrial sample received by pathologist of manual vacuum aspiration versus dilation & curettage in females presenting with abnormal uterine bleeding.  Methods:  It was a Randomized Controlled Trial performed in Department of Obstetrics & Gynecology, Lahore General Hospital, Lahore for one year  (April 3, 2020 till april 2, 2021). 390 females were randomly divided in two groups by lottery method. In group A, females had endometrial sampling with MVA. In group B, it was by dilatation and curettage by single surgical team. Efficacy was labelled when a pathologist could identify the endometrial epithelium, gland, and stroma, and make particular diagnosis of sample.  Results: The mean age of females in MVA group was 55.07 ± 6.10 years and  55.5 in D & C group  ± 6.07 years. The mean duration of AUB in MVA group was 17.26 ± 4.12 months and in D &C group, it was 17.44 ± 2.51 months. In MVA group, 170(87.2%) cases had efficacy and in D & C group efficacy,it was in 181(92.8%) cases, the frequency of efficacy in both groups was statistically same i.e. p-value > 0.05.  Conclusion: Although the efficacy in D & C group was high but was not statistically significantly different than MVA.So being simple and quick procedure,MVA can be used as an outdoor procedure, with less blood loss, without general anesthesia