Aporphine Alkaloids from Parabenzoin praecox (SIEB. et ZUCC.) NAKAI

A new aporphine alkaloid, praecoxine (1), was isolated from the root of Parabenzoin praecox (SIEB. et ZUCC.) NAKAI. The alkaloid was shown to be identical with N-methylhernagine, (S)-(+)-1, 2, 11-trimethoxy-10-hydroxyaporphine (1), on the basis of chemical transformations and spectral evidence. The occurrence of nandigerine (10) in the root and the stem wood was also proved.