The structure, biochemistry, and metabolism of osteoarthritic cartilage: a review of the literature.

PURPOSE To understand the possible significance of the presence of proteases, cytokines, growth factors, and arachidonic acid metabolites in the osteoarthritic temporomandibular joint (TMJ), the pathogenesis of TMJ osteoarthritis (OA) is discussed, based on knowledge of structure, biochemistry and metabolism of osteoarthritic cartilage in general, and a classification of TMJ OA is presented.

[1]  J. Pelletier,et al.  Are cytokines involved in osteoarthritic pathophysiology? , 1991, Seminars in arthritis and rheumatism.

[2]  G. Nuki,et al.  The aetiopathogenesis of osteoarthrosis , 1980 .

[3]  R. D'ambrosia,et al.  Identification of fibronectin in preparations of osteoarthritic human cartilage. , 1984, Connective tissue research.

[4]  C. H. Wilkes,et al.  Internal derangements of the temporomandibular joint. Pathological variations. , 1989, Archives of otolaryngology--head & neck surgery.

[5]  P. Westesson,et al.  Osteoarthritis and internal derangement of the temporomandibular joint: a light microscopic study. , 1986, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[6]  D. Howell,et al.  The pathogenesis of osteoarthritis. , 1986, Seminars in arthritis and rheumatism.

[7]  H. Schumacher,et al.  Atlas of Synovial Fluid Analysis and Crystal Identification , 1991 .

[8]  B. Stegenga,et al.  Temporomandibular joint osteoarthrosis and generalized joint hypermobility. , 1992, Cranio : the journal of craniomandibular practice.

[9]  H. Helminen.  Joint Loading: Biology and Health of Articular Fractures , 1988 .

[10]  J. Hollander.  ARTHRITIS AND ALLIED CONDITIONS , 1949 .

[11]  J. Pelletier,et al.  Human osteoarthritic chondrocytes possess an increased number of insulin-like growth factor 1 binding sites but are unresponsive to its stimulation. Possible role of IGF-1-binding proteins. , 1994, Arthritis and rheumatism.

[12]  Roland W. Moskowitz,et al.  Osteoarthritis: Diagnosis and Medical/Surgical Management , 1992 .

[13]  L. D. de Bont,et al.  Osteoarthritis of the temporomandibular joint: a light microscopic and scanning electron microscopic study of the articular cartilage of the mandibular condyle. , 1985, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[14]  M. Ehrlich.  Degradative enzyme systems in osteoarthritic cartilage , 1985, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[15]  L. D. de Bont,et al.  Ultrastructure of the articular cartilage of the mandibular condyle: aging and degeneration. , 1985, Oral surgery, oral medicine, and oral pathology.

[16]  D. Dean.  Proteinase-mediated cartilage degradation in osteoarthritis. , 1991, Seminars in arthritis and rheumatism.

[17]  L. D. de Bont,et al.  Normal cartilage structure, biochemistry, and metabolism: a review of the literature. , 1995, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[18]  B. Stegenga,et al.  Osteoarthrosis as the cause of craniomandibular pain and dysfunction: a unifying concept. , 1989, Journal of oral and maxillofacial surgery.

[19]  T. Ohishi,et al.  Quantitative analysis of crosslinks pyridinoline and pentosidine in articular cartilage of patients with bone and joint disorders. , 1994, Arthritis & Rheumatism.

[20]  J. Pelletier,et al.  Synovial membrane histology and immunopathology in rheumatoid arthritis and osteoarthritis. In vivo effects of antirheumatic drugs. , 1991, Arthritis and rheumatism.

[21]  William N. Kelley,et al.  Textbook of rheumatology , 1985 .