Analysis of Retinal Fundus Images for Classification of Glaucoma

An early sign of glaucoma can be seen from the presence of damage to the retinal nerve fibers. In retinal fundus image, the damage of nerve fibers is represented as a dark area. Several studies have been done with various analyses, one of those used texture. Thus, this paper aims to classify glaucomatous and healthy images by analyzing textures using first-order statistical approach. Initially, the image is cropped to get the region of interest (ROI), then the blood vessels and optic disc are segmented and removed to get candidate image. The features of candidate image will be extracted using first-order statistic. To obtain high accuracy, all features are evaluated by using Relief to select the efficient features. Selected features are used to classify the data into two classes. In this work, support vector machine (SVM), k-nearest neighbor (k-NN), linear discriminant analysis (LDA), and Naive Bayes are used. The performance results show that k-NN performs better with average of accuracy, sensitivity, specificity, PPV, and NPV are 93.3% than the others that are less than 90%.

[1]  K. Thangadurai,et al.  RELIEF: Feature Selection Approach , 2015 .

[2]  Igi Ardiyanto,et al.  Feature extraction based on laws' texture energy for lesion echogenicity classification of thyroid ultrasound images , 2017, 2017 International Conference on Computer, Control, Informatics and its Applications (IC3INA).

[3]  K.S. Park,et al.  Automated quantification of retinal nerve fiber layer atrophy in fundus photograph , 2004, The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[4]  B. Naveen Kumar,et al.  Detection of Glaucoma using image processing techniques: A review , 2016, 2016 International Conference on Microelectronics, Computing and Communications (MicroCom).

[5]  J. Jan,et al.  Analysis of retinal nerve fiber layer via Markov random fields in color fundus images , 2012, 2012 19th International Conference on Systems, Signals and Image Processing (IWSSIP).

[6]  Radford M. Neal Pattern Recognition and Machine Learning , 2007, Technometrics.

[7]  Constantin F. Aliferis,et al.  A Gentle Introduction to Support Vector Machines in Biomedicine:Volume 2: Case Studies and Benchmarks , 2012 .

[8]  Constantin F. Aliferis,et al.  A gentle introduction to support vector machines in biomedicine: Volume 1: Theory and methods , 2011 .

[9]  Wilhelm Burger,et al.  Digital Image Processing - An Algorithmic Introduction using Java , 2008, Texts in Computer Science.

[10]  Baihua Li,et al.  Automatic extraction of retinal features from colour retinal images for glaucoma diagnosis: A review , 2013, Comput. Medical Imaging Graph..

[11]  Igi Ardiyanto,et al.  Segmentation of optic disc on retinal fundus images using morphological reconstruction enhancement and active contour , 2016, 2016 2nd International Conference on Science in Information Technology (ICSITech).

[12]  Hiroshi Fujita,et al.  Detection of retinal nerve fiber layer defects in retinal fundus images using Gabor filtering , 2007, SPIE Medical Imaging.