CMOS monolithic chemiresistor array with microfluidic channel for micro gas chromatograph

A monolithic chemiresistor (CR) array micro-system with microfluidic channel for micro gas chromatograph (μGC) is presented in this paper. A CMOS readout chip was designed for amplifying and conditioning the signal of a 4×2 MPN-coated CR array fabricated on the surface of the CMOS chip. A micro glass lid with input and output capillary tubes was developed as a gas flow channel and mounted on the CMOS array, providing an interface to a micro flow column in a μGC platform. After all of the CMOS-compatible processing, the monolithic CR array was tested within a GC platform, and both the CR array and circuit were demonstrated to function as designed.

[1]  Nagel,et al.  Contact line deposits in an evaporating drop , 2000, Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics.

[2]  C. Kurdak,et al.  Nanoscale chemiresistor arrays with patterned nanoparticle interface layers for micro gas chromatography , 2009, TRANSDUCERS 2009 - 2009 International Solid-State Sensors, Actuators and Microsystems Conference.

[3]  Cagliyan Kurdak,et al.  Single-Phase Synthesis of Functionalized Gold Nanoparticles , 2004 .

[4]  R. Sacks,et al.  GC analysis of human breath with a series-coupled column ensemble and a multibed sorption trap. , 2003, Analytical chemistry.

[5]  Edward S. Kolesar,et al.  Review and summary of a silicon micromachined gas chromatography system , 1998, IEEE Transactions on Components, Packaging, and Manufacturing Technology: Part B.

[6]  E. Zellers,et al.  Microfabricated gas chromatograph for the selective determination of trichloroethylene vapor at sub-parts-per-billion concentrations in complex mixtures. , 2011, Analytical chemistry.

[7]  M.P. Rowe,et al.  Electrical noise in gold nanoparticle chemiresistors , 2008, 2008 IEEE Sensors.

[8]  Shirley Dex,et al.  JR 旅客販売総合システム(マルス)における運用及び管理について , 1991 .

[9]  E. Zellers,et al.  Model of vapor-induced resistivity changes in gold-thiolate monolayer-protected nanoparticle sensor films. , 2007, Analytical chemistry.

[10]  K. Wise,et al.  First-generation hybrid MEMS gas chromatograph. , 2005, Lab on a chip.

[11]  Mark Libardoni,et al.  Analysis of human breath samples with a multi-bed sorption trap and comprehensive two-dimensional gas chromatography (GCxGC). , 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[12]  Xiaoyi Mu,et al.  125ppm resolution and 120dB dynamic range nanoparticle chemiresistor array readout circuit , 2011, 2011 IEEE International Symposium of Circuits and Systems (ISCAS).

[13]  W.W. Wang,et al.  Analysis of Radiation Damage on a Monolithic CMOS-MEMS Printhead , 2007, 2007 IEEE Conference on Electron Devices and Solid-State Circuits.