In vivo demonstration of Pseudomonas aeruginosa biofilms as independent pharmacological microcompartments.

[1]  M. Skov,et al.  Cystic fibrosis – an example of personalized and precision medicine , 2019, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[2]  S. Gharavi,et al.  Screening, cloning and expression of a novel alginate lyase gene from P. aeruginosa TAG 48 and its antibiofilm effects on P. aeruginosa biofilm. , 2018, Microbial pathogenesis.

[3]  Mathias Müsken,et al.  Breaking the Vicious Cycle of Antibiotic Killing and Regrowth of Biofilm-Residing Pseudomonas aeruginosa , 2018, Antimicrobial Agents and Chemotherapy.

[4]  S. Häussler,et al.  Human airway mucus alters susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin , 2018, The Journal of antimicrobial chemotherapy.

[5]  N. Høiby,et al.  Modelling of ciprofloxacin killing enhanced by hyperbaric oxygen treatment in Pseudomonas aeruginosa PAO1 biofilms , 2018, PloS one.

[6]  D. Wangpraseurt,et al.  Tools for studying growth patterns and chemical dynamics of aggregated Pseudomonas aeruginosa exposed to different electron acceptors in an alginate bead model , 2018, npj Biofilms and Microbiomes.

[7]  S. A. Khonsary.  Guyton and Hall: Textbook of Medical Physiology , 2017, Surgical Neurology International.

[8]  M. Skov,et al.  Diagnosis of biofilm infections in cystic fibrosis patients , 2017, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[9]  M. Maciá,et al.  Antibiotic treatment of biofilm infections , 2017, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[10]  N. Høiby,et al.  Biofilms and host response – helpful or harmful , 2017, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[11]  M. Kühl,et al.  Pseudomonas aeruginosa Aggregate Formation in an Alginate Bead Model System Exhibits In Vivo-Like Characteristics , 2017, Applied and Environmental Microbiology.

[12]  A. Torres,et al.  Phenotypic shift in Pseudomonas aeruginosa populations from cystic fibrosis lungs after 2-week antipseudomonal treatment. , 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

[13]  K. Sneppen,et al.  Diffusion Retardation by Binding of Tobramycin in an Alginate Biofilm Model , 2016, PloS one.

[14]  N. Høiby,et al.  OligoG CF-5/20 Disruption of Mucoid Pseudomonas aeruginosa Biofilm in a Murine Lung Infection Model , 2016, Antimicrobial Agents and Chemotherapy.

[15]  N. Høiby,et al.  Antibiotic penetration and bacterial killing in a Pseudomonas aeruginosa biofilm model. , 2015, The Journal of antimicrobial chemotherapy.

[16]  John E. Hall,et al.  Guyton and Hall Textbook of Medical Physiology , 2015 .

[17]  A. Oliver,et al.  ESCMID guideline for the diagnosis and treatment of biofilm infections 2014. , 2015, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[18]  M. Ishii,et al.  Enzymatic Characterization and In Vivo Function of Five Terminal Oxidases in Pseudomonas aeruginosa , 2014, Journal of bacteriology.

[19]  T. Scheike,et al.  Polymorphonuclear Leukocytes Restrict Growth of Pseudomonas aeruginosa in the Lungs of Cystic Fibrosis Patients , 2014, Infection and Immunity.

[20]  Thomas Bjarnsholt,et al.  The in vivo biofilm. , 2013, Trends in microbiology.

[21]  T. Tolker-Nielsen,et al.  Extracellular DNA Shields against Aminoglycosides in Pseudomonas aeruginosa Biofilms , 2013, Antimicrobial Agents and Chemotherapy.

[22]  N. Høiby,et al.  Bead‐size directed distribution of Pseudomonas aeruginosa results in distinct inflammatory response in a mouse model of chronic lung infection , 2012, Clinical and experimental immunology.

[23]  W. Zimmerli,et al.  Pathogenesis and treatment concepts of orthopaedic biofilm infections. , 2012, FEMS immunology and medical microbiology.

[24]  S. Molin,et al.  Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa. , 2010, The Journal of infectious diseases.

[25]  Thomas Bjarnsholt,et al.  Antibiotic resistance of bacterial biofilms. , 2010, International journal of antimicrobial agents.

[26]  S. Molin,et al.  Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa. , 2009, The Journal of antimicrobial chemotherapy.

[27]  P. Stewart,et al.  Daptomycin Rapidly Penetrates a Staphylococcus epidermidis Biofilm , 2009, Antimicrobial Agents and Chemotherapy.

[28]  T. Tolker-Nielsen,et al.  Tolerance to the antimicrobial peptide colistin in Pseudomonas aeruginosa biofilms is linked to metabolically active cells, and depends on the pmr and mexAB‐oprM genes , 2008, Molecular microbiology.

[29]  Martin Schuster,et al.  Pseudomonas aeruginosa Biofilms Exposed to Imipenem Exhibit Changes in Global Gene Expression and β-Lactamase and Alginate Production , 2004, Antimicrobial Agents and Chemotherapy.

[30]  B. Ramsey,et al.  Effect of chronic intermittent administration of inhaled tobramycin on respiratory microbial flora in patients with cystic fibrosis. , 1999, The Journal of infectious diseases.

[31]  M S Pepe,et al.  Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. Cystic Fibrosis Inhaled Tobramycin Study Group. , 1999, The New England journal of medicine.

[32]  D. Bartels,et al.  Temperature Dependence of Oxygen Diffusion in H2O and D2O , 1996 .

[33]  P. Suci,et al.  Investigation of ciprofloxacin penetration into Pseudomonas aeruginosa biofilms , 1994, Antimicrobial Agents and Chemotherapy.

[34]  Martin Berzins,et al.  A Method for the Spatial Discretization of Parabolic Equations in One Space Variable , 1990, SIAM J. Sci. Comput..

[35]  G. Shand,et al.  Induction of experimental chronic Pseudomonas aeruginosa lung infection with P. aeruginosa entrapped in alginate microspheres , 1990, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[36]  Nichols,et al.  Inhibition of tobramycin diffusion by binding to alginate , 1988, Antimicrobial Agents and Chemotherapy.

[37]  P. Stewart,et al.  Mechanisms of antibiotic resistance in bacterial biofilms. , 2002, International journal of medical microbiology : IJMM.

[38]  N. Høiby,et al.  Treatment of chronic pseudomonas aeruginosa infection in cystic fibrosis patients with ceftazidime and tobramycin. , 1983, Scandinavian journal of infectious diseases.