Parkinson's disease‐like presentation of multiple system atrophy with poor response to STN stimulation: A clinicopathological case report

We report on a clinicopathological case of multiple system atrophy with good response to levodopa and subsequent development of motor complications. Because the subject complied with all the inclusion criteria (Core Assessment Program for Surgical Interventional Therapies in Parkinson's Disease), bilateral subthalamic nucleus deep brain stimulation electrodes were implanted. © 2004 Movement Disorder Society

[1]  P. Lantos,et al.  The definition of multiple system atrophy: a review of recent developments. , 1998, Journal of neuropathology and experimental neurology.

[2]  W. Poewe,et al.  Parkinsonism in multiple system atrophy: Natural history, severity (UPDRS‐III), and disability assessment compared with Parkinson's disease , 2002, Movement disorders : official journal of the Movement Disorder Society.

[3]  B Kleedorfer,et al.  The dopaminergic response in multiple system atrophy. , 1992, Journal of neurology, neurosurgery, and psychiatry.

[4]  A J Hughes,et al.  Clinicopathological aspects of Parkinson's disease. , 1997, European neurology.

[5]  P. Remy,et al.  Core assessment program for surgical interventional therapies in Parkinson's disease (CAPSIT‐PD) , 1999, Movement disorders : official journal of the Movement Disorder Society.

[6]  J. Hughes,et al.  Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. , 1992, Journal of neurology, neurosurgery, and psychiatry.

[7]  E. Tolosa,et al.  Presynaptic parkinsonism in multiple system atrophy mimicking Parkinson's disease: A clinicopathological case study , 2002, Movement disorders : official journal of the Movement Disorder Society.

[8]  Christine Haberler,et al.  No tissue damage by chronic deep brain stimulation in Parkinson's disease , 2000, Annals of neurology.

[9]  S. Daniel,et al.  Autonomic dysfunction in pathologically confirmed multiple system atrophy and idiopathic Parkinson's disease – a retrospective comparison , 1995, Acta neurologica Scandinavica.

[10]  E. Louis Vaccines to treat encephalitis lethargica: human experiments at the Neurological Institute of New York, 1929-1940. , 2002, Archives of neurology.

[11]  A. Rajput,et al.  Accuracy of Clinical Diagnosis in Parkinsonism — A Prospective Study , 1991, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[12]  R. Coppola,et al.  Lateralized differences in iodine-123-IBZM uptake in the basal ganglia in asymmetric Parkinson's disease. , 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[13]  Yoav Ben-Shlomo,et al.  The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service. , 2002, Brain : a journal of neurology.

[14]  W Reiche,et al.  [Dopamine (D2) receptor SPECT with 123I-iodobenzamide (IBZM) in diagnosis of Parkinson syndrome]. , 1995, Der Radiologe.

[15]  V. Fung,et al.  Postmortem analysis of bilateral subthalamic electrode implants in Parkinson's disease , 2002, Movement disorders : official journal of the Movement Disorder Society.

[16]  Loss of dopamine uptake sites and dopamine D2 receptors in striatonigral degeneration , 2000, Brain Research.

[17]  A. Bentivoglio,et al.  Multiple system atrophy presenting as parkinsonism: clinical features and diagnostic criteria. , 1995, Journal of neurology, neurosurgery, and psychiatry.

[18]  K. Chaudhuri,et al.  Autonomic dysfunction in movement disorders , 2001, Current opinion in neurology.

[19]  C. Mathias,et al.  Do published criteria improve clinical diagnostic accuracy in multiple system atrophy? , 2002, Neurology.

[20]  Daniel Tarsy,et al.  Adverse effects of subthalamic nucleus DBS in a patient with multiple system atrophy , 2003, Neurology.

[21]  N P Quinn,et al.  Clinical features and natural history of multiple system atrophy. An analysis of 100 cases. , 1994, Brain : a journal of neurology.

[22]  Hakan Widner,et al.  Deep brain stimulation for Parkinson's disease: Patient selection and evaluation , 2002, Movement disorders : official journal of the Movement Disorder Society.

[23]  Yasin Temel,et al.  Bilateral high-frequency stimulation of the subthalamic nucleus in patients with multiple system atrophy--parkinsonism. Report of four cases. , 2003, Journal of neurosurgery.

[24]  A. Rajput,et al.  Occurrence of resting tremor in Parkinson's disease , 1991, Neurology.

[25]  D. Burn,et al.  Multiple system atrophy: cellular and molecular pathology , 2001, Molecular pathology : MP.

[26]  W. Poewe,et al.  Dystonia in multiple system atrophy , 2002, Journal of neurology, neurosurgery, and psychiatry.