Experimental ENU Induced Brain Tumors with HpD and Dye Laser Light

It is well know that the Hematoporphyrin Derivative (HpD) accumulates preferentially in tumor tissues as compared with the normal tissues (Leonard and Beck, 1971; Lipson et al., 1961; Dougherty et al., 1976).

[1]  T. Dougherty,et al.  Determination of [3H]- and [14C]hematoporphyrin derivative distribution in malignant and normal tissue. , 1979, Cancer research.

[2]  T J Dougherty,et al.  Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor. , 1976, Cancer research.

[3]  J. H. Kinsey,et al.  Photoradiation therapy in the treatment of malignant brain tumors: a phase I (feasibility) study. , 1981, Neurosurgery.

[4]  S. Jacques,et al.  Development of a Protocol for Photoradiation Therapy of Malignant Brain Tumors: Part 1 , 1982 .

[5]  T J Dougherty,et al.  Photoradiation therapy. II. Cure of animal tumors with hematoporphyrin and light. , 1975, Journal of the National Cancer Institute.

[6]  D. Schiffer,et al.  Tumors of the nervous system induced by ethylnitrosourea administered either intracerebrally of subcutaneously to newborn rats. Morphological and biochemical characteristics. , 1972, Journal of neurosurgery.

[7]  C. Wilson,et al.  Photodynamic therapy of malignant tumours. , 1972, Lancet.

[8]  T J Dougherty,et al.  Energetics and efficiency of photoinactivation of murine tumor cells containing hematoporphyrin. , 1976, Cancer research.

[9]  J R Leonard,et al.  Hematoporphyrin fluorescence: An aid in diagnosis of malignant neoplasms , 1971, The Laryngoscope.

[10]  A. M. Olsen,et al.  The use of a derivative of hematoporphyrin in tumor detection. , 1961 .

[11]  J E Kaufman,et al.  Photoradiation therapy for the treatment of malignant tumors. , 1978, Cancer research.

[12]  J. Winkelman,et al.  Quantitative determination of porphyrin uptake by tumor tissue following parenteral administration. , 1960, Bulletin of the Johns Hopkins Hospital.

[13]  D. Sanderson,et al.  Tumor Fluorescence with Hematoporphyrin Derivative , 1977, The Annals of otology, rhinology, and laryngology.

[14]  J. Legge,et al.  Hematin compounds and bile pigments , 1949 .

[15]  S. Jacques,et al.  Development of a protocol for photoradiation therapy of malignant brain tumors: part 1. Photosensitization of normal brain tissue with hematoporphyrin derivative. , 1982, Neurosurgery.

[16]  E. Reddi,et al.  Time Dependence of Hematoporphyrin Distribution in Selected Tissues of Normal Rats and in Ascites Hepatoma , 1979, Tumori.