A Study of HLA Antigen Distribution in Families with Atopic Dermatitis

Seventeen children presenting with atopic dermatitis were HLA typed together with their parents and siblings. A total of 89 individuals was studied. No close link between HLA antigen distribution and clinical expression of atopy was demonstrated, and 14 HLA identical but disease‐free siblings were identified. An increase in the A1 B8 haplotype was observed in the families as a whole by comparison with a large control series.

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