Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations

Brian J. O’Roak, Pelagia Deriziotis, Choli Lee, Laura Vives, Jerrod J. Schwartz, Santhosh Girirajan, Emre Karakoc, Alexandra P. MacKenzie, Sarah B. Ng, Carl Baker, Mark J. Rieder, Deborah A. Nickerson, Raphael Bernier, Simon E. Fisher, Jay Shendure, and Evan E. Eichler Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA. Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom. Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA. Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands. Howard Hughes Medical Institute, Seattle, WA, USA.

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