Comparison of the Hinge Flow Fields of Two Bileaflet Mechanical Heart Valves under Aortic and Mitral Conditions

Background: Animal and clinical studies have shown that bileaflet mechanical heart valve designs are plagued by thromboembolic complications, with higher rates in the mitral than in the aortic position. This study evaluated the hinge flow dynamic of the 23 mm St. Jude Medical (SJM) Regent and the 23 mm CarboMedics (CM) valves under aortic conditions and compared these results with previous findings under mitral conditions. Method: Velocity and Reynolds shear stress fields were captured using two-component laser Doppler velocimetry. Results: Under aortic conditions, both the SJM and CM hinge flow fields exhibited a strong forward flow pattern during systole (maximum velocities of 2.31 and 1.75 m/s, respectively) and two main leakage jets during diastole (maximum velocities of 3.08 and 2.27 m/s, respectively). Conclusions: Aortic and mitral flow patterns within the two hinges were similar, but with a more dynamic flow during the forward flow phase under aortic conditions. Velocity magnitudes and shear stresses measured under mitral conditions were generally higher than those obtained in the aortic position, which may explain the higher rates of thromboembolism in the mitral implants when compared with the aortic implants.

[1]  A P Yoganathan,et al.  A comparison of the hinge and near-hinge flow fields of the St Jude medical hemodynamic plus and regent bileaflet mechanical heart valves. , 2000, The Journal of thoracic and cardiovascular surgery.

[2]  P. Lu,et al.  A reevaluation and discussion on the threshold limit for hemolysis in a turbulent shear flow. , 2001, Journal of biomechanics.

[3]  Ajit P Yoganathan,et al.  Microflow fields in the hinge region of the CarboMedics bileaflet mechanical heart valve design. , 2002, The Journal of thoracic and cardiovascular surgery.

[4]  J. Tingleff,et al.  Fourteen years' experience with the CarboMedics valve in young adults with aortic valve disease. , 2003, The Journal of heart valve disease.

[5]  G. Grunkemeier,et al.  Clinical evaluation of the carbomedics prosthesis: experience at providence health system in Portland. , 2002, The Journal of heart valve disease.

[6]  J. Skoularigis,et al.  Frequency and severity of intravascular hemolysis after left-sided cardiac valve replacement with Medtronic Hall and St. Jude Medical prostheses, and influence of prosthetic type, position, size and number. , 1993, The American journal of cardiology.

[7]  A P Yoganathan,et al.  A microstructural flow analysis within a bileaflet mechanical heart valve hinge. , 1996, The Journal of heart valve disease.

[8]  H Schmid-Schönbein,et al.  "Shear induced platelet activation"--a critical reappraisal. , 1985, Biorheology.

[9]  Jeffrey Thomas Ellis An in vitro investigation of the leakage and hinge flow fields through bileaflet mechanical heart valves and their relevance to thrombogenesis , 1999 .

[10]  A. Piwnica,et al.  Pivot design in bileaflet valves. , 1992, ASAIO journal.

[11]  Brandon R. Travis,et al.  An In Vitro Study of the Hinge and Near-Field Forward Flow Dynamics of the St. Jude Medical® Regent™ Bileaflet Mechanical Heart Valve , 2004, Annals of Biomedical Engineering.

[12]  A P Yoganathan,et al.  Velocity measurements and flow patterns within the hinge region of a Medtronic Parallel bileaflet mechanical valve with clear housing. , 1996, The Journal of heart valve disease.

[13]  Ajit Yoganathan,et al.  An in vitro assessment by means of laser Doppler velocimetry of the medtronic advantage bileaflet mechanical heart valve hinge flow. , 2003, The Journal of thoracic and cardiovascular surgery.

[14]  N H Hwang,et al.  Human red blood cell hemolysis in a turbulent shear flow: contribution of Reynolds shear stresses. , 1984, Biorheology.

[15]  Brandon Travis The effects of bileaflet prosthesis pivot geometry on turbulence and blood damage potential , 2001 .

[16]  R. Gibbons,et al.  ACC/AHA Guidelines for the Management of Patients With Valvular Heart Disease. Executive Summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With Valvular Heart Disease). , 1998, The Journal of heart valve disease.