Ethnopharmacology and bioinformatic combination for leads discovery: application to phospholipase A(2) inhibitors.
暂无分享,去创建一个
T. Scior | P. Bernard | M. Hibert | B. Didier | J. Berthon | B. Didier
[1] P Bernard,et al. Computer-aided molecular selection and design of natural bioactive molecules. , 1999, Current opinion in drug discovery & development.
[2] R. Irvine. How is the level of free arachidonic acid controlled in mammalian cells? , 1982, The Biochemical journal.
[3] M. Pintore,et al. Protein-based alignment in 3D QSAR of 26 indole inhibitors of human pancreatic phospholipase A2. , 2001, European journal of medicinal chemistry.
[4] M. Sundaralingam,et al. Structure of the complex of bovine pancreatic phospholipase A2 with a transition-state analogue. , 1998, Acta crystallographica. Section D, Biological crystallography.
[5] Katsutoshi Yamada,et al. Pyrrolidine inhibitors of human cytosolic phospholipase A2. Part 2: synthesis of potent and crystallized 4-triphenylmethylthio derivative 'pyrrophenone'. , 2001, Bioorganic & medicinal chemistry letters.
[6] K. H. Kalk,et al. Role of the N-terminus in the interaction of pancreatic phospholipase A2 with aggregated substrates. Properties and crystal structure of transaminated phospholipase A2. , 1983, Biochemistry.
[7] H. Friess,et al. Phospholipase A2 Isoforms in Acute Pancreatitis , 2001, Annals of surgery.
[8] Katsutoshi Yamada,et al. Pyrrolidine inhibitors of human cytosolic phospholipase A(2). , 2000, Journal of medicinal chemistry.
[9] M. Pintore,et al. A molecular modeling and 3D QSAR study of a large series of indole inhibitors of human non-pancreatic secretory phospholipase A2. , 2001, European journal of medicinal chemistry.
[10] M. Lehr. Synthesis, biological evaluation, and structure-activity relationships of 3-acylindole-2-carboxylic acids as inhibitors of the cytosolic phospholipase A2. , 1997, Journal of medicinal chemistry.
[11] J.-P. Wery,et al. Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2 , 1995, Nature Structural Biology.
[12] M. Recio,et al. Investigations on the steroidal anti-inflammatory activity of triterpenoids from Diospyros leucomelas. , 1995, Planta medica.
[13] J. D. Clark,et al. Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[14] W. Hol,et al. Structure of bovine pancreatic phospholipase A2 at 1.7A resolution. , 1981, Journal of molecular biology.
[15] G. Massiot,et al. Pharmacognosie: Phytochimie, Plantes Médicinales: : By J. Bruneton, 2nd Edn, Tec Doc, Paris, 1993. 928pp. 78OF ISBN 2-85206-911-3. , 1994 .
[16] M. Sundaralingam,et al. Crystal structure of the complex of bovine pancreatic phospholipase A2 with the inhibitor 1-hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol,. , 1997, Biochemistry.
[17] I. Posadas,et al. Cavernolide: a new inhibitor of human sPLA2 sharing unusual chemical features. , 2000, Life sciences.
[18] Philippe Bernard,et al. Automated docking of 82 N-benzylpiperidine derivatives to mouse acetylcholinesterase and comparative molecular field analysis with 'natural' alignment , 1999, J. Comput. Aided Mol. Des..
[19] R. Mayer,et al. New insights on mammalian phospholipase A2(s); comparison of arachidonoyl‐selective and ‐nonselective enzymes , 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[20] Y. Hannun,et al. Role of phospholipases in generating lipid second messengers in signal transduction 1 , 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.