Alport syndrome from bench to bedside: the potential of current treatment beyond RAAS blockade and the horizon of future therapies.
暂无分享,去创建一个
[1] R. Girgert,et al. Antifibrotic, nephroprotective effects of paricalcitol versus calcitriol on top of ACE-inhibitor therapy in the COL4A3 knockout mouse model for progressive renal fibrosis. , 2014, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[2] K. Nakanishi,et al. Milder clinical aspects of X-linked Alport syndrome in men positive for the collagen IV α5 chain. , 2014, Kidney international.
[3] J. Miner,et al. Feasibility of repairing glomerular basement membrane defects in Alport syndrome. , 2014, Journal of the American Society of Nephrology : JASN.
[4] H. Dweep,et al. Evidence for activation of the unfolded protein response in collagen IV nephropathies. , 2014, Journal of the American Society of Nephrology : JASN.
[5] K. Kadler,et al. Chemical chaperone treatment reduces intracellular accumulation of mutant collagen IV and ameliorates the cellular phenotype of a COL4A2 mutation that causes haemorrhagic stroke , 2013, Human molecular genetics.
[6] M. Takasato,et al. Recreating kidney progenitors from pluripotent cells , 2014, Pediatric Nephrology.
[7] K. Lemley,et al. A Novel Source of Cultured Podocytes , 2013, PloS one.
[8] M. Takasato,et al. Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors. , 2013, Journal of the American Society of Nephrology : JASN.
[9] J. Papillon,et al. Nephrin missense mutations: induction of endoplasmic reticulum stress and cell surface rescue by reduction in chaperone interactions , 2013, Physiological reports.
[10] Y. Kikkawa,et al. Laminin β2 gene missense mutation produces endoplasmic reticulum stress in podocytes. , 2013, Journal of the American Society of Nephrology : JASN.
[11] M. Walther,et al. Diagnosis of Alport syndrome—search for proteomic biomarkers in body fluids , 2013, Pediatric Nephrology.
[12] D. Rubel,et al. Alport syndrome—insights from basic and clinical research , 2013, Nature Reviews Nephrology.
[13] Jie Ding,et al. Expert guidelines for the management of Alport syndrome and thin basement membrane nephropathy. , 2013, Journal of the American Society of Nephrology : JASN.
[14] Chad A. Cowan,et al. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells , 2013, Nature Communications.
[15] C. Licht,et al. An update on the pathomechanisms and future therapies of Alport syndrome , 2013, Pediatric Nephrology.
[16] H. Anders,et al. Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non‐inflammatory glomerular injury , 2012, The Journal of pathology.
[17] F. Dekker,et al. Outcomes of male patients with Alport syndrome undergoing renal replacement therapy. , 2012, Clinical journal of the American Society of Nephrology : CJASN.
[18] P. Kerr,et al. The Directed Differentiation of Human iPS Cells into Kidney Podocytes , 2012, PloS one.
[19] B. Kasinath,et al. TGFβ-Stimulated MicroRNA-21 Utilizes PTEN to Orchestrate AKT/mTORC1 Signaling for Mesangial Cell Hypertrophy and Matrix Expansion , 2012, PloS one.
[20] M. Burke,et al. Atypical fractures associated with bisphosphonate use post‐renal transplantation , 2012, Nephrology.
[21] D. Warburton,et al. Injection of amniotic fluid stem cells delays progression of renal fibrosis. , 2012, Journal of the American Society of Nephrology : JASN.
[22] Jie Ding,et al. Clinical practice recommendations for the treatment of Alport syndrome: a statement of the Alport Syndrome Research Collaborative , 2012, Pediatric Nephrology.
[23] T. Friede,et al. Early angiotensin-converting enzyme inhibition in Alport syndrome delays renal failure and improves life expectancy. , 2012, Kidney international.
[24] Aaron N. Chang,et al. MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways , 2012, Science Translational Medicine.
[25] S. Ricardo,et al. Mesenchymal stem cells in kidney inflammation and repair , 2012, Nephrology.
[26] Stefano Da Sacco,et al. Regenerative medicine of the kidney. , 2011, Advanced drug delivery reviews.
[27] H. Anders,et al. Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-α-mediated podocyte loss. , 2011, Kidney international.
[28] M. Kretzler,et al. Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease. , 2010, Matrix biology : journal of the International Society for Matrix Biology.
[29] Timothy M. Williams,et al. Macrophages in renal development, injury, and repair. , 2010, Seminars in nephrology.
[30] J. Folkman,et al. Stem cell therapies benefit Alport syndrome. , 2009, Journal of the American Society of Nephrology : JASN.
[31] P. S. St. John,et al. Cellular origins of type IV collagen networks in developing glomeruli. , 2009, Journal of the American Society of Nephrology : JASN.
[32] Clair Baldock,et al. Collagens at a glance , 2007, Journal of Cell Science.
[33] A. Perkins,et al. In vitro differentiation of murine embryonic stem cells toward a renal lineage. , 2007, Differentiation; research in biological diversity.
[34] S. Segerer,et al. Nephroprotective effect of the HMG-CoA-reductase inhibitor cerivastatin in a mouse model of progressive renal fibrosis in Alport syndrome. , 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[35] R. Poulsom,et al. Bone Marrow‐Derived Cells Contribute to Podocyte Regeneration and Amelioration of Renal Disease in a Mouse Model of Alport Syndrome , 2006, Stem cells.
[36] R. Kalluri,et al. Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[37] J. Kramer,et al. Cells differentiated from mouse embryonic stem cells via embryoid bodies express renal marker molecules. , 2006, Differentiation; research in biological diversity.
[38] Takahiko Kobayashi,et al. Wnt4-transformed mouse embryonic stem cells differentiate into renal tubular cells. , 2005, Biochemical and biophysical research communications.
[39] K. Tryggvason,et al. Alport's syndrome, Goodpasture's syndrome, and type IV collagen. , 2003, The New England journal of medicine.
[40] S. Sasaki,et al. Intracellular mislocalization of mutant podocin and correction by chemical chaperones , 2003, Histochemistry and Cell Biology.
[41] P. S. St. John,et al. Laminin-1 reexpression in Alport mouse glomerular basement membranes1 , 2003 .
[42] E. Schulze-Lohoff,et al. Preemptive ramipril therapy delays renal failure and reduces renal fibrosis in COL4A3-knockout mice with Alport syndrome. , 2003, Kidney international.
[43] P. Zeitlin,et al. Therapeutic approaches to repair defects in deltaF508 CFTR folding and cellular targeting. , 2002, Advanced drug delivery reviews.
[44] O. Gross,et al. Meta-analysis of genotype-phenotype correlation in X-linked Alport syndrome: impact on clinical counselling. , 2002, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[45] R. Kalluri,et al. Integrin α1β1 and Transforming Growth Factor-β1 Play Distinct Roles in Alport Glomerular Pathogenesis and Serve as Dual Targets for Metabolic Therapy , 2000 .
[46] Y. Sado,et al. Type IV Collagen of the Glomerular Basement Membrane , 2000, The Journal of Biological Chemistry.
[47] S. Angers,et al. Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants. , 2000, The Journal of clinical investigation.
[48] R. Kalluri,et al. Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy. , 2000, The American journal of pathology.
[49] R. Kalluri,et al. Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis. , 1997, The Journal of clinical investigation.
[50] J. Engel,et al. A substitution of cysteine for glycine 748 of the alpha 1 chain produces a kink at this site in the procollagen I molecule and an altered N-proteinase cleavage site over 225 nm away. , 1988, The Journal of biological chemistry.
[51] Alport Ac. HEREDITARY FAMILIAL CONGENITAL HAEMORRHAGIC NEPHRITIS , 1927 .