Crohn's Disease Manifesting as Acute Appendicitis: Case Report and Review of the Literature

Crohn’s Disease (CD) is one of the two clinical presentations of Inflammatory Bowel Disease (IBD) which involves the GI tract from the mouth to the anus, presenting a transmural pattern of inflammation. CD has been described as being a heterogenous disorder with multifactorial etiology. The diagnosis is based on anamnesis, physical examination, laboratory finding, imaging and endoscopic findings. There have been less than 200 cases of Crohn’s disease confined to the appendix since it was first described by Meyerding and Bertram in 1953. We present the case of a 24 year old male, who presented with acute onset, right lower quadrant pain, mimicking acute appendicitis with histopathological report of Crohn’s disease confined to the appendix. Terrazas-Espitia Francisco1*, Molina-Dávila David1, Pérez-Benítez Omar2, Espinosa-Dorado Rodrigo2 and Zárate-Osorno Alejandra3 1Division of Digestive Surgery, Hospital Español, Mexico 2Department of General Surgery Resident, Hospital Español, Mexico 3Department of Pathology, Hospital Español, Mexico

[1]  U. Jayarajah,et al.  Isolated Crohn's Disease of the Appendix Presenting as Acute Appendicitis in a 60-Year-Old South Asian Female: A Case Report, Review of Literature, and Follow-Up Recommendations , 2019, Case reports in surgery.

[2]  A. Mattia,et al.  Actinomyces in Crohn’s‐like appendicitis , 2019, Histopathology.

[3]  J. D. Hernandez,et al.  Actynomicosis of the abdomen mimicking acute appendicitis , 2019, International Surgery Journal.

[4]  H. Matsubara,et al.  Crohn's Disease Presenting as Granulomatous Appendicitis , 2019, Case Reports in Gastroenterology.

[5]  V. Neychev,et al.  Acute Granulomatous Appendicitis and Lower Gastrointestinal Bleeding as the Presenting Features of Crohn's Disease , 2019, Cureus.

[6]  J. Yamamoto-Furusho,et al.  Incidence and prevalence of inflammatory bowel disease in Mexico from a nationwide cohort study in a period of 15 years (2000–2017) , 2019, Medicine.

[7]  G. Nash,et al.  Unexpected Findings at Appendectomy , 2019, The SAGES Manual of Colorectal Surgery.

[8]  K. Tepelenis,et al.  Appendiceal Crohn’s disease: a case report , 2019, European Journal of Medical Case Reports.

[9]  Gottrand Frédéric,et al.  Tuberculous colon perforation mimicking acute appendicitis: A case report and review of the literature , 2018, Clinical case reports.

[10]  S. Tomić,et al.  Signet Ring Carcinoma of the Appendix Presenting as Crohn's Disease in a Young Male , 2018, Case Reports in Gastroenterology.

[11]  Jana G Hashash,et al.  A comprehensive review and update on Crohn's disease. , 2017, Disease-a-month : DM.

[12]  A. Cheifetz,et al.  Crohn Disease: Epidemiology, Diagnosis, and Management , 2017, Mayo Clinic proceedings.

[13]  D. Jeyaratnam,et al.  Another mistaken case of appendicitis , 2015, BMJ Case Reports.

[14]  T. Karttunen,et al.  Endothelial Fas-Ligand in Inflammatory Bowel Diseases and in Acute Appendicitis , 2015, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[15]  Hanan Khalil,et al.  Crohn’s disease: a clinical update , 2015, Therapeutic advances in gastroenterology.

[16]  K. Darge,et al.  Pediatric Small Bowel Crohn Disease: Correlation of US and MR Enterography. , 2015, Radiographics : a review publication of the Radiological Society of North America, Inc.

[17]  S. Paik,et al.  Appendiceal Crohn's disease clinically presenting as acute appendicitis. , 2014, World journal of clinical cases.

[18]  R. Briseño,et al.  Crohn’s appendicitis, presentation of a new case , 2012 .

[19]  M. Farthing,et al.  Ileal Crohn's disease is best treated by surgery , 2002, Gut.

[20]  I. Leodolter.  [Crohn's disease]. , 1967, Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete.