Hearing loss associated with smoking and occupational noise exposure in a Japanese metal working company

The effects of smoking on hearing loss within the context of atherosclerosis was assessed, and the statistical interaction of occupational noise evaluated. A cross-sectional study was conducted in 397 Japanese males working at a metal factory, aged 21–66 years, in a periodical health checkup. The following information was obtained: two smoking indices of smoking status and Brinkman index, occupational noise exposures and atherosclerotic risk factors (body mass index, blood pressure, serum cholesterol, hemoglobin A1c, atherosclerosis index). Hearing acuity was measured at 4 kHz using a pure-tone audiometer in a quiet room. Among the total subjects, 55 (13.9%) were identified as having hearing loss at 4 kHz, and 151 (38.0%) were currently exposed to occupational noise. When adjusted for age and occupational noise exposure, odds ratios (95% confidence intervals) of hearing loss were 3.16 (1.04, 9.62) for past smokers and 3.39 (1.05, 11.01) for heavy smokers (Brinkman index >750 cigarettes per day × number of years), compared with never-smokers. Statistical interaction of occupational noise exposure was insignificant with the association between smoking and hearing loss. When including atherosclerotic risk factors in a multiple model, there were no significant associations between hearing loss and either smoking or any other factors (i.e., occupational noise and atherosclerotic factors). Smoking was found to be associated with hearing loss beyond occupational noise exposure, and this association seemed to be masked by atherosclerotic factors, suggesting that the direction of the atherosclerotic effect on the relationship might need to be explored between smoking and hearing impairment.

[1]  J. Verbeek,et al.  Non-auditory effects of noise in industry , 1987, International archives of occupational and environmental health.

[2]  K. Rampal,et al.  Multiplicative effect of smoking and age on hearing impairment. , 1998, American journal of otolaryngology.

[3]  R. Klein,et al.  Cigarette smoking and hearing loss: the epidemiology of hearing loss study. , 1998, JAMA.

[4]  A. Siegelaub,et al.  Hearing loss in adults: relation to age, sex, exposure to loud noise, and cigarette smoking. , 1974, Archives of environmental health.

[5]  B. Karlsmose,et al.  A Five-Year Longitudinal Study of Hearing in a Danish Rural Population Aged 31–50 Years , 2000, British journal of audiology.

[6]  K. Matthews,et al.  Occupational noise exposure, noise-induced hearing loss, and the epidemiology of high blood pressure. , 1985, American journal of epidemiology.

[7]  P. Levine.  An Acute Effect of Cigarette Smoking on Platelet Function: A Possible Link Between Smoking and Arterial Thrombosis , 1973, Circulation.

[8]  T. Dawber,et al.  Primary prevention of the atherosclerotic diseases , 1970 .

[9]  T. Mizoue,et al.  Combined effect of smoking and occupational exposure to noise on hearing loss in steel factory workers , 2003, Occupational and environmental medicine.

[10]  D. R. Cunningham,et al.  Influence of Cigarette Smoking on Extra‐High‐Frequency Auditory Thresholds , 1983, Ear and hearing.

[11]  A. Allen,et al.  PERIPHERAL VASCULAR DISEASE , 1940 .

[12]  O Manninen.  Cardiovascular changes and hearing threshold shifts in men under complex exposures to noise, whole body vibrations, temperatures and competition-type psychic load , 1985, International archives of occupational and environmental health.

[13]  W. Weiss.  How smoking affects hearing. , 1970, Medical times.

[14]  Ibrahim As,et al.  Cigarette smoking and hearing loss. , 1983 .

[15]  N. Tsubota,et al.  Lung cancer treated surgically in patients <50 years of age. , 2001, Chest.

[16]  S Sone,et al.  Expiratory and inspiratory chest computed tomography and pulmonary function tests in cigarette smokers. , 1999, The European respiratory journal.

[17]  D. Kleinbaum,et al.  Applied Regression Analysis and Other Multivariate Methods , 1978 .

[18]  P G Smith,et al.  Association between Atherosclerotic Diseases and Carboxyhaemoglobin Levels in Tobacco Smokers , 1973, British medical journal.

[19]  A. Tamakoshi,et al.  Smoking and drinking habits as risk factors for hearing loss in the elderly: epidemiological study of subjects undergoing routine health checks in Aichi, Japan. , 2001, Public health.

[20]  J Starck,et al.  Age and noise-induced hearing loss , 2001, Scandinavian audiology.

[21]  K. Makishima.  Arteriolar Sclerosis as a Cause of Presbycusis , 1978, Otolaryngology.

[22]  K. Tatara,et al.  Cigarette Smoking and Risk for Hearing Impairment: A Longitudinal Study in Japanese Male Office Workers , 2000, Journal of occupational and environmental medicine.

[23]  M. Griffin,et al.  Cigarette smoking, occupational exposure to noise, and self reported hearing difficulties , 2004, Occupational and Environmental Medicine.

[24]  Jong-tsun Huang,et al.  Comparison of blood pressure in deaf-mute children and children with normal hearing: association between noise and blood pressure , 1993, International archives of occupational and environmental health.