Effect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studies
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John A Wagner | Rajesh Krishna | Arthur J Bergman | J. Chodakewitz | A. Bergman | J. Wagner | R. Krishna | K. Gottesdiener | C. Chavez-Eng | Jeffrey Chodakewitz | M. Gutierrez | Daniel M Bloomfield | J. Cote | D. Bloomfield | Keith M Gottesdiener | Matt S Anderson | Bo Jin | Marissa Fallon | Josee Cote | Kim Rosko | Cynthia Chavez-Eng | Ryan Lutz | Maria Gutierrez | James Doherty | Fredrick Bieberdorf | Matt S. Anderson | R. Lutz | B. Jin | J. Doherty | K. Rosko | F. Bieberdorf | Marissa Fallon | M. Fallon | Bo Jin
[1] M. Caulfield,et al. Effects of torcetrapib in patients at high risk for coronary events , 2008 .
[2] C. Shear,et al. Inhibition of Cholesteryl Ester Transfer Protein by Torcetrapib Modestly Increases Macrophage Cholesterol Efflux to HDL , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[3] Jean-Claude Tardif,et al. Effect of torcetrapib on the progression of coronary atherosclerosis. , 2007, The New England journal of medicine.
[4] J. Kastelein,et al. Designs of RADIANCE 1 and 2:carotid ultrasound studies comparing the effects of torcetrapib/atorvastatin with atorvastatin alone on atherosclerosis* , 2007, Current medical research and opinion.
[5] J. Tanne. Pfizer stops clinical trials of heart drug , 2006, BMJ : British Medical Journal.
[6] A. Tall,et al. The failure of torcetrapib: was it the molecule or the mechanism? , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[7] J. Mckenney,et al. Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels on a background of atorvastatin. , 2006, Journal of the American College of Cardiology.
[8] J. Mckenney,et al. Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels. , 2006, Journal of the American College of Cardiology.
[9] A. Tall,et al. HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway. , 2006, The Journal of clinical investigation.
[10] M. Milad,et al. Model-based development of gemcabene, a new lipid-altering agent , 2005, The AAPS Journal.
[11] M. Trip,et al. Effectiveness of inhibition of cholesteryl ester transfer protein by JTT-705 in combination with pravastatin in type II dyslipidemia. , 2005, The American journal of cardiology.
[12] T. Sand,et al. Raising High-Density Lipoprotein in Humans Through Inhibition of Cholesteryl Ester Transfer Protein: An Initial Multidose Study of Torcetrapib , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[13] E. Stein,et al. Pharmacotherapy for dyslipidaemia – current therapies and future agents , 2003, Expert opinion on pharmacotherapy.
[14] D. Rader,et al. Cholesteryl Ester Transfer Protein: A Novel Target for Raising HDL and Inhibiting Atherosclerosis , 2003, Arteriosclerosis, thrombosis, and vascular biology.
[15] A. Zwinderman,et al. Efficacy and Safety of a Novel Cholesteryl Ester Transfer Protein Inhibitor, JTT-705, in Humans: A Randomized Phase II Dose-Response Study , 2002, Circulation.
[16] J. Wittes,et al. Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial. , 2001, JAMA.
[17] S. Yamashita,et al. Pros and cons of inhibiting cholesteryl ester transfer protein , 2000, Current opinion in lipidology.
[18] H. Suzuki,et al. A low prevalence of coronary heart disease among subjects with increased high-density lipoprotein cholesterol levels, including those with plasma cholesteryl ester transfer protein deficiency. , 1998, Preventive medicine.
[19] A. Tall,et al. Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels. , 1996, The Journal of clinical investigation.
[20] A. Tall. Plasma cholesteryl ester transfer protein. , 1993, Journal of lipid research.
[21] A. Tall,et al. Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation. , 1990, The New England journal of medicine.
[22] D. Gordon,et al. High-density lipoprotein--the clinical implications of recent studies. , 1989, The New England journal of medicine.
[23] A. Tall,et al. Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins , 1989, Nature.
[24] 康二 梶波,et al. Cholesteryl-Ester Transfer Activityの欠損を示す家族性高HDL血症の1家系 , 1987 .
[25] A. Tall,et al. Purification and characterization of a human plasma cholesteryl ester transfer protein. , 1987, The Journal of biological chemistry.
[26] N. Miller. Associations of high-density lipoprotein subclasses and apolipoproteins with ischemic heart disease and coronary atherosclerosis. , 1987, American heart journal.
[27] H. Mabuchi,et al. Deficiency of serum cholesteryl-ester transfer activity in patients with familial hyperalphalipoproteinaemia. , 1985, Atherosclerosis.
[28] G. Miller,et al. PLASMA-HIGH-DENSITY-LIPOPROTEIN CONCENTRATION AND DEVELOPMENT OF ISCHÆMIC HEART-DISEASE , 1975, The Lancet.
[29] R. Levy,et al. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. , 1972, Clinical chemistry.
[30] D. Grobbee,et al. Eff ect of Torcetrapib on Progression of Carotid Atherosclerosis in Heterozygous Familial Hyper- cholesterolemia , 2007 .
[31] D. Cutler,et al. Effect of Torcetrapib on the Progression of Coronary Atherosclerosis , 2007 .
[32] M. Dewey,et al. Clinical vignette. Aortocoronary collateral. , 2007, European heart journal.
[33] J. Mckenney,et al. P Pharmacotherapy of HDL and LDL fficacy and Safety of Torcetrapib , Novel Cholesteryl Ester Transfer Protein nhibitor , in Individuals With Below-Average igh-Density Lipoprotein Cholesterol Levels , 2006 .