Polyoxometalate-Graphene Nanocomposite Modified Electrode for Electrocatalytic Detection of Ascorbic Acid

Phosphomolybdate functionalized graphene nanocomposite (PMo12-GS) has been successfully formed on a glassy carbon electrode (GCE) for the detection of ascorbic acid (AA). The obtained PMo12-GS modified GCE, was characterized by cyclic voltammetry, electro- chemical impedance spectroscopy, scanning electron mi- croscopy (SEM) and Fourier transform infrared (FT-IR) spectroscopy and compared with GCE, GS modified GCE, and PMo12 modified GCE. It shows an increased current and a decrease in over-potential of ~ 210 mV. The amperometric signals are linearly proportional to the AA concentration in a wide concentration range from 1 � 10 6 Mt o 8 � 10 3 M, with a detection limit of 0.5 � 10 6 M. The PMo12-GS modified electrode was employed for the determination of the AA level in vitamin C tab- lets, with recoveries between 96.3 and 100.8 %.

[1]  Balasubramanian Viswanathan,et al.  Synthesis and Characterization of Metal Nanoparticle Embedded Conducting Polymer–Polyoxometalate Composites , 2007, Nanoscale Research Letters.

[2]  A. Walcarius.  Electrocatalysis, sensors and biosensors in analytical chemistry based on ordered mesoporous and macroporous carbon-modified electrodes , 2012 .

[3]  C. Rao,et al.  Composites of graphene and other nanocarbons with organogelators assembled through supramolecular interactions. , 2012, Chemistry.

[4]  J. Ahn,et al.  Multi-walled carbon nanotubes for the immobilization of enzyme in glucose biosensors , 2003 .

[5]  E. Steckhan,et al.  Electrochemical Properties of Polyoxometalates as Electrocatalysts. , 1998, Chemical reviews.

[6]  Dan Du,et al.  Graphene-based materials for biosensing and bioimaging , 2012 .

[7]  G. Maracas,et al.  Impedance labelless detection-based polypyrrole DNA biosensor. , 2005, Frontiers in bioscience : a journal and virtual library.

[8]  Leroy Cronin,et al.  Polyoxometalates: building blocks for functional nanoscale systems. , 2010, Angewandte Chemie.

[9]  E. Wang,et al.  Heteropolyacid-assisted fabrication of carbon nanostructures under ambient conditions. , 2009, Chemical communications.

[10]  Y. Tsai,et al.  Graphene modified basal and edge plane pyrolytic graphite electrodes for electrocatalytic oxidation of hydrogen peroxide and β-nicotinamide adenine dinucleotide , 2009 .

[11]  F. Du,et al.  Nitrogen-Doped Carbon Nanotube Arrays with High Electrocatalytic Activity for Oxygen Reduction , 2009, Science.

[12]  X. Chu,et al.  Electro-oxidation of ascorbic acid at bismuth sulfide nanorod modified glassy carbon electrode , 2012 .

[13]  Dan Du,et al.  Biosensor based on Prussian blue nanocubes/reduced graphene oxide nanocomposite for detection of organophosphorus pesticides. , 2012, Nanoscale.

[14]  Geng Wu,et al.  An electrochemical ascorbic acid sensor based on palladium nanoparticles supported on graphene oxide. , 2012, Analytica chimica acta.

[15]  Mianqi Xue,et al.  Processing of graphene for electrochemical application: noncovalently functionalize graphene sheets with water-soluble electroactive methylene green. , 2009, Langmuir : the ACS journal of surfaces and colloids.

[16]  Dongxue Han,et al.  Electrochemical determination of NADH and ethanol based on ionic liquid-functionalized graphene. , 2010, Biosensors & bioelectronics.

[17]  Zaiping Guo,et al.  Rapid Synthesis of Amino Acid Polyoxometalate Nanotubes by One‐Step Solid‐State Chemical Reaction at Room Temperature , 2006 .

[18]  Yuyan Shao,et al.  Graphene Based Electrochemical Sensors and Biosensors: A Review , 2010 .

[19]  Shen-ming Chen,et al.  Electrochemical selective determination of ascorbic acid at redox active polymer modified electrode derived from direct blue 71. , 2008, Biosensors & bioelectronics.

[20]  Itamar Willner,et al.  Integrated Enzyme‐Based Biofuel Cells–A Review , 2009 .

[21]  Fengchun Yang,et al.  An electrochemical biosensor for ascorbic acid based on carbon-supported PdNi nanoparticles. , 2013, Biosensors & bioelectronics.

[22]  Chang Ming Li,et al.  In situ synthesized heteropoly acid/polyaniline/graphene nanocomposites to simultaneously boost both double layer- and pseudo-capacitance for supercapacitors. , 2012, Physical chemistry chemical physics : PCCP.

[23]  Martin M. F. Choi,et al.  L-Ascorbic acid biosensing assay from enzyme-immobilized pig bladder membrane as a novel platform , 2013 .

[24]  Yuyan Shao,et al.  Nitrogen-doped graphene and its application in electrochemical biosensing. , 2010, ACS nano.

[25]  Yuehe Lin,et al.  Study of Inhibition, Reactivation and Aging Processes of Pesticides Using Graphene Nanosheets/Gold Nanoparticles-Based Acetylcholinesterase Biosensor , 2012 .

[26]  Bao-hang Han,et al.  Graphene‐Based Nanoporous Materials Assembled by Mediation of Polyoxometalate Nanoparticles , 2010 .

[27]  A. Wiȩckowski,et al.  Network Films Composed of Conducting Polymer-Linked and Polyoxometalate-Stabilized Platinum Nanoparticles , 2004 .

[28]  Jin Luo,et al.  Electrochemical analysis of ascorbic acid using copper nanoparticles/polyaniline modified glassy carbon electrode , 2010 .

[29]  A. Yu,et al.  A glassy carbon electrode modified with a polyaniline doped with silicotungstic acid and carbon nanotubes for the sensitive amperometric determination of ascorbic acid , 2013, Microchimica Acta.