Федеральное государственное бюджетное учреждение «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний» Сибирского отделения Российской академии медицинских наук, Кемерово, Россия

Натрийуретические пептиды (НУП) являются важными биомаркерами в диагностике и определении прогноза у пациентов с сердечной недостаточностью (СН). Оценка динамики концентрации НУП (BNP, Nt -proBNP) может быть использована в качестве критерия успешности проводимой терапии. так, при достижении целевых уровней НУП можно прогнозировать благоприятный исход заболевания. В настоящее время лечение СН с учетом уровней НУП является частью рекомендаций по лечению СН (класс IIа) и улучшению ее исхода (класс IIб) в США, однако такой подход не используется в российских клиниках. Цель. Представить современный взгляд на возможность использования НУП для оценки эффективности проводимой терапии пациентов с СН. Ключевые слова: натрийуретические пептиды, сердечная недостаточность, оценка эффективности терапии.

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