Auditory evoked potentials (N1 wave) as indices of cortical development

The neurophysiology of sensory and cognitive processing can be studied with a high degree of temporal resolution by recording evoked potentials (EPs) on the scalp. These potentials are extracted from the EEG by averaging a number of EEG samples time-locked to the event. They offer the possibility of measuring the function of numerous neural systems in a completely noninvasive fashion. Moreover, evoked potentials can be assessed in paradigms which do not require the active participation of the subject. These advantages make them easily applicable to children and therefore particularly suitable for the study of normal and abnormal brain development. One of the most important uses of EPs is assessment of auditory function. Applications are quite extensive, particularly in developmental disorders. Indeed, in disorders such as those including language and communicative impairment, it is important to identify the possible disturbances which can affect various levels of the central auditory system.

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