Wearable devices for health-related quality of life evaluation

Medical and biomedical research fields are paying even closer attention to the health-related quality of life (HRQoL). Furthermore, having a precise snapshot of a subject’s daily life and of the related vital parameters (heart rate, ECG pattern, movement, sleeping habits, etc.) helps medical and social structures having a precise scenario of the elders. HRQoL is largely assessed by means of patient-reported outcomes (PROs), a flawed methodology if used for quality of life evaluation. Several kinds of biometrical parameters have been demonstrated to be significant in the evaluation of the HRQoL alongside with the PROs. It has also been shown that individual quality of life is tightly related to the patient frailty status (PFS). Pre-frail elders need a constant monitoring to catch any drift in their frailty markers for foretelling a possible shift in their PFS. A scalable hardware/software architecture has been realized with the aim of gathering vital parameters keeping low cumbersomeness. Systems should be able to gather, post-process and analyze monitored person’s vital parameters but, at the same time, patient therapies’ effectiveness can be constantly monitored and examined in deep. In the next future, the widely spreading of these systems will produce an huge quantity of structured, semi- or quasi-structured data. In order to reduce the complexity and manage such data, new storage techniques and new processing algorithms are desirable. Aim of this paper is to describe a novel architecture and an example of the algorithm to reduce the complexity of the non-structured data like a single-channel ECG.

[1]  Mario Magliulo,et al.  Bluetooth devices for the optimization ofpatients' workflow in a radiation oncology department , 2015, 2015 E-Health and Bioengineering Conference (EHB).

[2]  H. Gholam-Hosseini,et al.  ECG noise cancellation using digital filters , 1998, Proceedings of the 2nd International Conference on Bioelectromagnetism (Cat. No.98TH8269).

[3]  Ingela Wiklund,et al.  Assessment of patient‐reported outcomes in clinical trials: the example of health‐related quality of life , 2004, Fundamental & clinical pharmacology.

[4]  P. A. Lynn Recursive digital filters for biological signals , 2006, Medical & biological engineering.

[5]  M. Ramasubba Reddy,et al.  A transform domain SVD filter for suppression of muscle noise artefacts in exercise ECG's , 2000, IEEE Transactions on Biomedical Engineering.

[6]  Mahesh S. Chavan Suppression of Baseline Wander and power line interference in ECG using Digital IIR Filter , 2008 .

[7]  Madhuchhanda Mitra,et al.  Empirical mode decomposition based ECG enhancement and QRS detection , 2012, Comput. Biol. Medicine.

[8]  Abhishek Mathur,et al.  FPGA implementation of fast FIR low pass filter for EMG removal from ECG signal , 2010, 2010 International Conference on Power, Control and Embedded Systems.

[9]  Mirza Mansoor Baig,et al.  Smart Health Monitoring Systems: An Overview of Design and Modeling , 2013, Journal of Medical Systems.

[10]  Mahadev D. Uplane,et al.  Interference reduction in ECG using digital FIR filters based on rectangular window , 2008 .

[11]  Masao Kanamori,et al.  The relationship between fear of falling, activities of daily living and quality of life among elderly individuals. , 2002, Nursing & health sciences.

[12]  E. Skordalakis,et al.  Bottom-up approach to the ECG pattern-recognition problem , 2006, Medical and Biological Engineering and Computing.

[13]  Phil Jevon Procedure for recording a standard 12-lead electrocardiogram. , 2010, British journal of nursing.

[14]  C. Schwartz,et al.  Methodological approaches for assessing response shift in longitudinal health-related quality-of-life research. , 1999, Social science & medicine.

[15]  Max E. Valentinuzzi,et al.  Artifact removal from EEG signals using adaptive filters in cascade , 2007 .

[16]  J. Robine,et al.  Looking forward to a general theory on population aging. , 2004, Tijdschrift voor gerontologie en geriatrie.

[17]  B. L. Beattie,et al.  Frailty in elderly people: an evolving concept. , 1994, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[18]  Rose Anne Kenny,et al.  A Frailty Instrument for primary care: findings from the Survey of Health, Ageing and Retirement in Europe (SHARE) , 2010, BMC geriatrics.

[19]  Brian Lawlor,et al.  Frailty and Quality of Life for People With Alzheimer’s Dementia and Mild Cognitive Impairment , 2012, American journal of Alzheimer's disease and other dementias.

[20]  Paola Pierleoni,et al.  An Android-Based Heart Monitoring System for the Elderly and for Patients with Heart Disease , 2014, International journal of telemedicine and applications.

[21]  Brigitte Santos-Eggimann,et al.  The Lausanne cohort Lc65+: a population-based prospective study of the manifestations, determinants and outcomes of frailty , 2008, BMC geriatrics.

[22]  T. Strandberg,et al.  Frailty in elderly people , 2007, The Lancet.

[23]  Ann Bowling,et al.  Dimensions and correlates of quality of life according to frailty status: a cross-sectional study on community-dwelling older adults referred to an outpatient geriatric service in Italy , 2010, Health and quality of life outcomes.

[24]  Stefan Höfer,et al.  Response shift masks the treatment impact on patient reported outcomes (PROs): the example of individual quality of life in edentulous patients , 2005, Health and quality of life outcomes.

[25]  J. Walston,et al.  Frailty--the search for underlying causes. , 2004, Science of aging knowledge environment : SAGE KE.

[26]  Carrie D. Heitzler,et al.  Physical activity levels among children aged 9-13 years— United States, 2002. (Report from the Centers for Disease Control and Prevention, Morbidity and Mortality Weekly Report, MMWR. 2003;52:785-788) , 2003 .

[27]  Seema,et al.  Comparison of different approaches for removal of baseline wander from ECG signal , 2011, ICWET.

[28]  M. Fain,et al.  Frailty: an emerging geriatric syndrome. , 2007, The American journal of medicine.

[29]  P Finbarr Allen,et al.  Health and Quality of Life Outcomes , 2003 .

[30]  Sarah Barnes,et al.  Methods for Assessing Quality of Life and Well-Being in Frail Older People , 2002 .

[31]  H. Amièva,et al.  The Phenotype of Frailty and Health-Related Quality of Life. , 2013, The Journal of frailty & aging.

[32]  J. A. van Alsté,et al.  ECG baseline wander reduction using linear phase filters , 1986 .

[33]  Mario Magliulo,et al.  Cardiac monitoring of frail oncological outpatient using wearable devices , 2017, 2017 E-Health and Bioengineering Conference (EHB).

[34]  S R Tunis,et al.  Development of a guidance for including patient-reported outcomes (PROs) in post-approval clinical trials of oncology drugs for comparative effectiveness research (CER). , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[35]  R. Gobbens,et al.  The relationship between frailty, anxiety and depression, and health-related quality of life in elderly patients with heart failure , 2015, Clinical interventions in aging.

[36]  Thomas M Gill,et al.  Transitions between frailty states among community-living older persons. , 2006, Archives of internal medicine.

[37]  M. Magliulo,et al.  Novel technique radio frequency identification (RFID) based to manage patient flow in a radiotherapy department , 2012, Proceedings of 2012 IEEE-EMBS International Conference on Biomedical and Health Informatics.

[38]  Zeli Gao,et al.  Design of ECG Signal Acquisition and Processing System , 2012, 2012 International Conference on Biomedical Engineering and Biotechnology.

[39]  Priyanka Kakria,et al.  A Real-Time Health Monitoring System for Remote Cardiac Patients Using Smartphone and Wearable Sensors , 2015, International journal of telemedicine and applications.

[40]  Ming-Feng Yeh,et al.  Real-time ECG telemonitoring system design with mobile phone platform , 2008 .

[41]  Tomoyuki Yambe,et al.  A mobile communications system for home-visit medical services: The Electronic Doctor's Bag , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[42]  K. Chan,et al.  Characteristic wave detection in ECG signal using morphological transform , 2005, BMC cardiovascular disorders.

[43]  J. Woo,et al.  Social Determinants of Frailty , 2005, Gerontology.

[44]  J. van Alsté,et al.  Removal of Base-Line Wander and Power-Line Interference from the ECG by an Efficient FIR Filter with a Reduced Number of Taps , 1985, IEEE Transactions on Biomedical Engineering.

[45]  Katrien G Luijkx,et al.  The Tilburg Frailty Indicator: psychometric properties. , 2010, Journal of the American Medical Directors Association.

[46]  Victor de Pinto Filters for the reduction of baseline wander and muscle artifact in the ECG. , 1992 .

[47]  K. F. Tan,et al.  Detection of the QRS complex, P wave and T wave in electrocardiogram , 2000 .

[48]  Abhar Rukh Husain,et al.  Life Expectancy in Developing Countries: A Cross-Section Analysis , 2002 .

[49]  Yasunori Sumi,et al.  Factors influencing oral health-related quality of life (OHRQoL) among the frail elderly residing in the community with their family. , 2010, Archives of gerontology and geriatrics.

[50]  W. Strawbridge,et al.  Antecedents of frailty over three decades in an older cohort. , 1998, The journals of gerontology. Series B, Psychological sciences and social sciences.

[51]  Soliman A. Mahmoud,et al.  Low-Noise Low-Pass Filter for ECG Portable Detection Systems with Digitally Programmable Range , 2013, Circuits Syst. Signal Process..

[52]  Masamine Jimba,et al.  Rapid increase in Japanese life expectancy after World War II. , 2010, Bioscience trends.

[53]  L. Fried,et al.  Frailty in older adults: evidence for a phenotype. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.

[54]  I. I. Christov,et al.  High-pass filtering of ECG signals using QRS elimination , 2006, Medical and Biological Engineering and Computing.