Ultrasound Standard Plane Detection Using a Composite Neural Network Framework

Ultrasound (US) imaging is a widely used screening tool for obstetric examination and diagnosis. Accurate acquisition of fetal standard planes with key anatomical structures is very crucial for substantial biometric measurement and diagnosis. However, the standard plane acquisition is a labor-intensive task and requires operator equipped with a thorough knowledge of fetal anatomy. Therefore, automatic approaches are highly demanded in clinical practice to alleviate the workload and boost the examination efficiency. The automatic detection of standard planes from US videos remains a challenging problem due to the high intraclass and low interclass variations of standard planes, and the relatively low image quality. Unlike previous studies which were specifically designed for individual anatomical standard planes, respectively, we present a general framework for the automatic identification of different standard planes from US videos. Distinct from conventional way that devises hand-crafted visual features for detection, our framework explores in- and between-plane feature learning with a novel composite framework of the convolutional and recurrent neural networks. To further address the issue of limited training data, a multitask learning framework is implemented to exploit common knowledge across detection tasks of distinctive standard planes for the augmentation of feature learning. Extensive experiments have been conducted on hundreds of US fetus videos to corroborate the better efficacy of the proposed framework on the difficult standard plane detection problem.

[1]  Xiao Liu,et al.  Stacked deep polynomial network based representation learning for tumor classification with small ultrasound image dataset , 2016, Neurocomputing.

[2]  Jürgen Schmidhuber,et al.  Long Short-Term Memory , 1997, Neural Computation.

[3]  A. Abuhamad,et al.  Automated retrieval of standard diagnostic fetal cardiac ultrasound planes in the second trimester of pregnancy: a prospective evaluation of software , 2007, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[4]  B. Benacerraf,et al.  Three‐dimensional Fetal Sonography , 2002, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[5]  Yoshua Bengio,et al.  Gradient Flow in Recurrent Nets: the Difficulty of Learning Long-Term Dependencies , 2001 .

[6]  Hao Chen,et al.  3D Fully Convolutional Networks for Intervertebral Disc Localization and Segmentation , 2016, MIAR.

[7]  Michael I. Jordan,et al.  Learning Transferable Features with Deep Adaptation Networks , 2015, ICML.

[8]  AIUM Practice Guideline for the Performance of Obstetric Ultrasound Examinations , 2010, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[9]  Y. Ville,et al.  Feasibility and reproducibility of an image‐scoring method for quality control of fetal biometry in the second trimester , 2005, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[10]  Anthony Maida,et al.  Natural Image Bases to Represent Neuroimaging Data , 2013, ICML.

[11]  Stefan Carlsson,et al.  CNN Features Off-the-Shelf: An Astounding Baseline for Recognition , 2014, 2014 IEEE Conference on Computer Vision and Pattern Recognition Workshops.

[12]  Christoph Meinel,et al.  Deep Learning for Medical Image Analysis , 2018, Journal of Pathology Informatics.

[13]  Stefan C. Kremer,et al.  Recurrent Neural Networks , 2013, Handbook on Neural Information Processing.

[14]  Quoc V. Le,et al.  Sequence to Sequence Learning with Neural Networks , 2014, NIPS.

[15]  Xin Yang,et al.  Standard plane localization in ultrasound by radial component model and selective search. , 2014, Ultrasound in medicine & biology.

[16]  Hao Chen,et al.  Automatic Detection of Cerebral Microbleeds From MR Images via 3D Convolutional Neural Networks , 2016, IEEE Transactions on Medical Imaging.

[17]  Shihui Ying,et al.  Histopathological Image Classification With Color Pattern Random Binary Hashing-Based PCANet and Matrix-Form Classifier , 2017, IEEE Journal of Biomedical and Health Informatics.

[18]  Alex Graves,et al.  Supervised Sequence Labelling , 2012 .

[19]  Dumitru Erhan,et al.  Going deeper with convolutions , 2014, 2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[20]  Geoffrey E. Hinton,et al.  ImageNet classification with deep convolutional neural networks , 2012, Commun. ACM.

[21]  Yoshua Bengio,et al.  Gradient-based learning applied to document recognition , 1998, Proc. IEEE.

[22]  Hao Chen,et al.  Standard Plane Localization in Fetal Ultrasound via Domain Transferred Deep Neural Networks , 2015, IEEE Journal of Biomedical and Health Informatics.

[23]  Trevor Darrell,et al.  Caffe: Convolutional Architecture for Fast Feature Embedding , 2014, ACM Multimedia.

[24]  Éric Gaussier,et al.  A Probabilistic Interpretation of Precision, Recall and F-Score, with Implication for Evaluation , 2005, ECIR.

[25]  Lisa M. Gangarosa,et al.  The Practice of Ultrasound: A Step-by-Step Guide to Abdominal Scanning , 2005 .

[26]  Alex Graves,et al.  Generating Sequences With Recurrent Neural Networks , 2013, ArXiv.

[27]  Gustavo Carneiro,et al.  Detection and Measurement of Fetal Anatomies from Ultrasound Images using a Constrained Probabilistic Boosting Tree , 2008, IEEE Transactions on Medical Imaging.

[28]  Jian Sun,et al.  Deep Residual Learning for Image Recognition , 2015, 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[29]  Rob Fergus,et al.  Visualizing and Understanding Convolutional Networks , 2013, ECCV.

[30]  J. Alison Noble,et al.  Integration of Local and Global Features for Anatomical Object Detection in Ultrasound , 2012, MICCAI.

[31]  Guigang Zhang,et al.  Deep Learning , 2016, Int. J. Semantic Comput..

[32]  Bai Ying Lei,et al.  Bridging Computational Features Toward Multiple Semantic Features with Multi-task Regression: A Study of CT Pulmonary Nodules , 2016, MICCAI.

[33]  D. Taverner Diagnostic Ultrasound , 1966, Nature.

[34]  Wojciech Zaremba,et al.  Learning to Execute , 2014, ArXiv.

[35]  Dong Ni,et al.  FUIQA: Fetal Ultrasound Image Quality Assessment With Deep Convolutional Networks , 2017, IEEE Transactions on Cybernetics.

[36]  Thomas Brox,et al.  U-Net: Convolutional Networks for Biomedical Image Segmentation , 2015, MICCAI.

[37]  Fei-Fei Li,et al.  Deep visual-semantic alignments for generating image descriptions , 2014, 2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[38]  Zhang Yi,et al.  Output convergence analysis for a class of delayed recurrent neural networks with time-varying inputs , 2006, IEEE Trans. Syst. Man Cybern. Part B.

[39]  N. Dudley,et al.  The importance of quality management in fetal measurement , 2002, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[40]  Dorin Comaniciu,et al.  Automatic Detection and Measurement of Structures in Fetal Head Ultrasound Volumes Using Sequential Estimation and Integrated Detection Network (IDN) , 2014, IEEE Transactions on Medical Imaging.

[41]  Hao Chen,et al.  Automatic Fetal Ultrasound Standard Plane Detection Using Knowledge Transferred Recurrent Neural Networks , 2015, MICCAI.

[42]  R. Adler,et al.  Utility of Portable Ultrasound in a Community in Ghana , 2008, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[43]  Sharif Razzaque,et al.  Localizing target structures in ultrasound video - A phantom study , 2013, Medical Image Anal..

[44]  Hao Chen,et al.  Mitosis Detection in Breast Cancer Histology Images via Deep Cascaded Networks , 2016, AAAI.

[45]  Hao Chen,et al.  Fetal Abdominal Standard Plane Localization through Representation Learning with Knowledge Transfer , 2014, MLMI.

[46]  Stephen Grossberg,et al.  Recurrent neural networks , 2013, Scholarpedia.

[47]  Michael S. Bernstein,et al.  ImageNet Large Scale Visual Recognition Challenge , 2014, International Journal of Computer Vision.

[48]  Pascal Vincent,et al.  Representation Learning: A Review and New Perspectives , 2012, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[49]  Tianfu Wang,et al.  Intelligent scanning: automated standard plane selection and biometric measurement of early gestational sac in routine ultrasound examination. , 2012, Medical physics.

[50]  Hao Chen,et al.  Iterative Multi-domain Regularized Deep Learning for Anatomical Structure Detection and Segmentation from Ultrasound Images , 2016, MICCAI.

[51]  Ronald M. Summers,et al.  Deep Convolutional Neural Networks for Computer-Aided Detection: CNN Architectures, Dataset Characteristics and Transfer Learning , 2016, IEEE Transactions on Medical Imaging.

[52]  J. Alison Noble,et al.  Searching for Structures of Interest in an Ultrasound Video Sequence , 2014, MLMI.

[53]  Fengfu Li,et al.  Biologically Inspired Model for Visual Cognition Achieving Unsupervised Episodic and Semantic Feature Learning , 2016, IEEE Transactions on Cybernetics.

[54]  Ronald J. Williams,et al.  Gradient-based learning algorithms for recurrent networks and their computational complexity , 1995 .

[55]  Xin Yang,et al.  Selective Search and Sequential Detection for Standard Plane Localization in Ultrasound , 2013, Abdominal Imaging.

[56]  Bai Ying Lei,et al.  Automatic Scoring of Multiple Semantic Attributes With Multi-Task Feature Leverage: A Study on Pulmonary Nodules in CT Images , 2017, IEEE Transactions on Medical Imaging.

[57]  Hao Chen,et al.  DCAN: Deep contour‐aware networks for object instance segmentation from histology images , 2017, Medical Image Anal..

[58]  Trevor Darrell,et al.  Long-term recurrent convolutional networks for visual recognition and description , 2014, 2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[59]  J. Alison Noble,et al.  Quality control of fetal ultrasound images: Detection of abdomen anatomical landmarks using AdaBoost , 2011, 2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro.

[60]  Hao Chen,et al.  3D Deeply Supervised Network for Automatic Liver Segmentation from CT Volumes , 2016, MICCAI.

[61]  Sida I. Wang,et al.  Dropout Training as Adaptive Regularization , 2013, NIPS.