Variability in FMRI : A Re-Examination of Intersession

We revisit the McGonigle et al (2000) paper on intersession variability, showing that, contrary to one popular interpretation of the original paper, intersession variability is not necessarily high. We also highlight how evaluating variability on the basis of thresholded single-session images alone can be misleading. Finally, we show that the use of different first-level pre-processing, time-series statistics and registration analysis methodologies can give significantly different intersession analysis results.

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