Roadmap for Conducting Neuroscience Research in the COVID-19 Era and Beyond: Recommendations From the SNACC Research Committee

The coronavirus disease 2019 (COVID-19) pandemic has impacted many aspects of neuroscience research. At the 2020 Society of Neuroscience in Anesthesiology and Critical Care (SNACC) Annual Meeting, the SNACC Research Committee met virtually to discuss research challenges encountered during the COVID-19 pandemic along with possible strategies for facilitating research activities. These challenges and recommendations are included in this Consensus Statement. The objectives are to: (1) provide an overview of the disruptions and challenges to neuroscience research caused by the COVID-19 pandemic, and; (2) put forth a set of consensus recommendations for strengthening research sustainability during and beyond the current pandemic. Specific recommendations are highlighted for adapting laboratory and human subject study activities to optimize safety. Complementary research activities are also outlined for both laboratory and clinical researchers if specific investigations are impossible because of regulatory or societal changes. The role of virtual platforms is discussed with respect to fostering new collaborations, scheduling research meetings, and holding conferences such that scientific collaboration and exchange of ideas can continue. Our hope is for these recommendations to serve as a valuable resource for investigators in the neurosciences and other research disciplines for current and future research disruptions.

[1]  C. Conrad,et al.  Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 , 2020, Nature Neuroscience.

[2]  S. Besnard,et al.  Electroencephalographic Abnormalites in SARS-CoV-2 Patients , 2020, Frontiers in Neurology.

[3]  D. Sharma The World of Virtual Conferencing: Is the Pandemic Paving the Path? , 2020, Journal of neurosurgical anesthesiology.

[4]  A. Lok,et al.  Opinion: A risk–benefit framework for human research during the COVID-19 pandemic , 2020, Proceedings of the National Academy of Sciences.

[5]  M. Marshall The lasting misery of coronavirus long-haulers , 2020, Nature.

[6]  Benjamin M Marlin,et al.  Digitizing clinical trials. , 2020, NPJ digital medicine.

[7]  Yian Yin,et al.  Unequal effects of the COVID-19 pandemic on scientists , 2020, Nature Human Behaviour.

[8]  Mingyi Zhao,et al.  Evaluation of psychological stress in scientific researchers during the 2019–2020 COVID-19 outbreak in China , 2020, PeerJ.

[9]  K. Fargen,et al.  Neuroendovascular clinical trials disruptions due to COVID-19. Potential future challenges and opportunities , 2020, Journal of NeuroInterventional Surgery.

[10]  B. Payrastre,et al.  Thromboembolic events and Covid-19 , 2020, Advances in Biological Regulation.

[11]  P. Kochanek,et al.  Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Study Design and Rationale , 2020, Neurocritical Care.

[12]  F. Werneck,et al.  Impact of COVID-19 on academic mothers , 2020, Science.

[13]  K. Hashimoto,et al.  Nervous system involvement after infection with COVID-19 and other coronaviruses , 2020, Brain, Behavior, and Immunity.

[14]  L. Cottler,et al.  Improving community participation in clinical and translational research: CTSA Sentinel Network proof of concept study , 2020, Journal of Clinical and Translational Science.

[15]  Tsutomu Hashikawa,et al.  The neuroinvasive potential of SARS‐CoV2 may play a role in the respiratory failure of COVID‐19 patients , 2020, Journal of medical virology.

[16]  Springer Fachmedien Wiesbaden,et al.  Service , 2018, Wirtschaftsinformatik Manag..

[17]  A. Slooter,et al.  Recognition of Delirium in Postoperative Elderly Patients: A Multicenter Study , 2017, Journal of the American Geriatrics Society.

[18]  S. Kheterpal Clinical research using an information system: the multicenter perioperative outcomes group. , 2011, Anesthesiology clinics.

[19]  R. S. Jones,et al.  Surgeon compensation: "Pay for performance," the American College of Surgeons National Surgical Quality Improvement Program, the Surgical Care Improvement Program, and other considerations. , 2005, Surgery.

[20]  K. Jenpanich,et al.  [Drug administration]. , 1976, Thai journal of nursing.