Effects of encephalo-duro-arterio-synangiosis on childhood moyamoya patients--swift disappearance of ischemic attacks and maintenance of mental capacity.

The effect of encephalo-duro-arterio-synangiosis (EDAS) upon chronic cerebrovascular ischemia in 65 pediatric moyamoya patients was evaluated by the postoperative interval before complete disappearance of ischemic attacks and changes in pre- and postoperative intelligence (IQ) or development quotients (DQ). The ischemic attacks disappeared after a mean period of 239 days, in three-fourths of patients within a year and in about one-fourth within the second year. This was very fast compared with the natural course of the disease. There was no significant difference in DQ/IQ before and after the operation. The mentally normal (IQ/DQ greater than or equal to 86) population in the postoperative patients was greater than in the natural course of the disease, although fewer in the preoperative group. This shows that EDAS delayed or prevented the deterioration in mental capacity usually present but often overlooked in the natural course of pediatric moyamoya disease.

[1]  R. A. Solomon,et al.  Cerebral Revascularization: A Review , 1989, Neurosurgery.

[2]  Y. Miyasaka,et al.  Cranial burr hole for revascularization in moyamoya disease. , 1989, Journal of neurosurgery.

[3]  T. Nariai,et al.  Changes in cerebral hemodynamics following encephalo-duro-arterio-synangiosis (EDAS) in young patients with moyamoya disease. , 1989, Surgical neurology.

[4]  T. Nariai,et al.  A study of ameliorated cases at early postEDAS period in moyamoya disease. , 1988 .

[5]  S. Chuang,et al.  The surgical treatment of childhood moyamoya disease. , 1987, Journal of neurosurgery.

[6]  Y. Fukuyama,et al.  Clinical and cerebral angiographic evolutions of idiopathic progressive occlusive disease of the circle of willis (“Moyamoya” disease) in children , 1985, Brain and Development.

[7]  K. Hasuo,et al.  Prognosis of occlusive disease of the circle of Willis (moyamoya disease) in children. , 1985, Pediatric neurology.

[8]  S. Balagura,et al.  Treatment of moyamoya disease by cerebroarteriosynangiosis. , 1985, Surgical neurology.

[9]  S. Takeuchi,et al.  Intelligence in Children With Moyamoya Disease: Evaluation After Surgical Treatments With Special Reference to Changes in Cerebral Blood Flow , 1984, Stroke.

[10]  A. Destée,et al.  Encephaloarteriosynangiosis in the treatment of chronic cerebral ischemia: preliminary report based on 30 cases. , 1983, Surgical neurology.

[11]  H. Abe,et al.  Reconstructive Operation for Moyamoya Disease , 1983 .

[12]  H. Abe,et al.  [Reconstructive operation for moyamoya disease. Surgical indication for the hemorrhagic type, and preferable operative methods]. , 1983, Neurologia medico-chirurgica.

[13]  M. Aoyagi,et al.  Angiographic demonstration of cerebral revascularization after encephalo-duro-arterio-synangiosis (EDAS) performed on pediatric moyamoya patients. , 1982, The Bulletin of Tokyo Medical and Dental University.

[14]  M. Aoyagi,et al.  A new surgical treatment of moyamoya disease in children: a preliminary report. , 1981, Surgical neurology.

[15]  Y. Yoshii.  [Follow-up of "Moyamoya" disease. Clinical prognosis]. , 1977, No to shinkei = Brain and nerve.

[16]  T. Kudo.  Spontaneous occlusion of the circle of Willis , 1968, Neurology.