Regulators of endocytosis maintain localized receptor tyrosine kinase signaling in guided migration.

[1]  T. Meyer,et al.  A local coupling model and compass parameter for eukaryotic chemotaxis. , 2005, Developmental cell.

[2]  N. Perrimon,et al.  The PDGF/VEGF receptor controls blood cell survival in Drosophila. , 2004, Developmental cell.

[3]  E. Raz,et al.  Autonomous modes of behavior in primordial germ cell migration. , 2004, Developmental cell.

[4]  G. Borisy,et al.  Cell Migration: Integrating Signals from Front to Back , 2003, Science.

[5]  P. Rørth,et al.  Hrs mediates downregulation of multiple signalling receptors in Drosophila , 2003, EMBO reports.

[6]  R. Lehmann,et al.  Tre1, a G Protein-Coupled Receptor, Directs Transepithelial Migration of Drosophila Germ Cells , 2003, PLoS biology.

[7]  Guido Tarone,et al.  Positional control of cell fate through joint integrin/receptor protein kinase signaling. , 2003, Annual review of cell and developmental biology.

[8]  H. Pelham,et al.  Slow Diffusion of Proteins in the Yeast Plasma Membrane Allows Polarity to Be Maintained by Endocytic Cycling , 2003, Current Biology.

[9]  R. Chiusaroli,et al.  Deletion of the gene encoding c-Cbl alters the ability of osteoclasts to migrate, delaying resorption and ossification of cartilage during the development of long bones. , 2003, Developmental biology.

[10]  J. Segall,et al.  Local signaling by the EGF receptor , 2003, The Journal of cell biology.

[11]  Philip D Stahl,et al.  The Src Homology 2 Domain of Rin1 Mediates Its Binding to the Epidermal Growth Factor Receptor and Regulates Receptor Endocytosis* , 2003, Journal of Biological Chemistry.

[12]  M. Affolter,et al.  Signaling systems, guided cell migration, and organogenesis: insights from genetic studies in Drosophila. , 2003, Developmental biology.

[13]  Peter J. Verveer,et al.  EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation , 2003, Nature Cell Biology.

[14]  Lani Wu,et al.  Spontaneous Cell Polarization Through Actomyosin-Based Delivery of the Cdc42 GTPase , 2003, Science.

[15]  C. Nüsslein-Volhard,et al.  A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor , 2003, Nature.

[16]  D. Meyer,et al.  Guidance of Primordial Germ Cell Migration by the Chemokine SDF-1 , 2002, Cell.

[17]  P. Devreotes,et al.  Temporal and spatial regulation of chemotaxis. , 2002, Developmental cell.

[18]  Cornelis J Weijer,et al.  Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8. , 2002, Developmental cell.

[19]  P. Rørth,et al.  Invasive cell migration is initiated by guided growth of long cellular extensions , 2002, Nature Cell Biology.

[20]  Shuichi Takayama,et al.  Lateral propagation of EGF signaling after local stimulation is dependent on receptor density. , 2002, Developmental cell.

[21]  P. Rørth Initiating and guiding migration: lessons from border cells. , 2002, Trends in cell biology.

[22]  Hugo J Bellen,et al.  When cell biology meets development: endocytic regulation of signaling pathways. , 2002, Genes & development.

[23]  Richard A. Firtel,et al.  Spatial and Temporal Regulation of 3-Phosphoinositides by PI 3-Kinase and PTEN Mediates Chemotaxis , 2002, Cell.

[24]  P. Devreotes,et al.  Tumor Suppressor PTEN Mediates Sensing of Chemoattractant Gradients , 2002, Cell.

[25]  I. Madshus,et al.  Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes , 2002, Nature Cell Biology.

[26]  I. Dikic,et al.  Cbl–CIN85–endophilin complex mediates ligand-induced downregulation of EGF receptors , 2002, Nature.

[27]  H. Bellen,et al.  Hrs Regulates Endosome Membrane Invagination and Tyrosine Kinase Receptor Signaling in Drosophila , 2002, Cell.

[28]  P. Rørth,et al.  Guidance of Cell Migration by the Drosophila PDGF/VEGF Receptor , 2001, Cell.

[29]  P. Stahl,et al.  Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1. , 2001, Developmental cell.

[30]  D. Montell Command and control: regulatory pathways controlling invasive behavior of the border cells , 2001, Mechanisms of Development.

[31]  W. Langdon,et al.  Cbl: many adaptations to regulate protein tyrosine kinases , 2001, Nature Reviews Molecular Cell Biology.

[32]  G. Hime,et al.  Dynamic expression of alternate splice forms of D-cbl during embryogenesis , 2001, Mechanisms of Development.

[33]  P. Rørth,et al.  Cloning and expression of sprint, a Drosophila homologue of RIN1 , 2001, Mechanisms of Development.

[34]  P. Rørth,et al.  Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis. , 2001, Science.

[35]  P J Verveer,et al.  Quantitative imaging of lateral ErbB1 receptor signal propagation in the plasma membrane. , 2000, Science.

[36]  T. Schüpbach,et al.  D-cbl, a Negative Regulator of the Egfr Pathway, Is Required for Dorsoventral Patterning in Drosophila Oogenesis , 2000, Cell.

[37]  S. Schmid,et al.  Regulation of signal transduction by endocytosis. , 2000, Current opinion in cell biology.

[38]  H. Band,et al.  The Evolutionarily Conserved N-terminal Region of Cbl Is Sufficient to Enhance Down-regulation of the Epidermal Growth Factor Receptor* , 2000, The Journal of Biological Chemistry.

[39]  T. Hunter,et al.  The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase. , 1999, Science.

[40]  M. Komada,et al.  Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis. , 1999, Genes & development.

[41]  R. Klein,et al.  Eph receptors and ephrins: effectors of morphogenesis. , 1999, Development.

[42]  Z. Kam,et al.  c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. , 1998, Genes & development.

[43]  C. Lowell,et al.  A β1 integrin signaling pathway involving Src‐family kinases, Cbl and PI‐3 kinase is required for macrophage spreading and migration , 1998, The EMBO journal.

[44]  R. Burdine,et al.  EGL-17(FGF) expression coordinates the attraction of the migrating sex myoblasts with vulval induction in C. elegans. , 1998, Development.

[45]  G. Rubin,et al.  Systematic gain-of-function genetics in Drosophila. , 1998, Development.

[46]  B. Shilo,et al.  In situ activation pattern of Drosophila EGF receptor pathway during development. , 1997, Science.

[47]  M. White,et al.  Protein binding and signaling properties of RIN1 suggest a unique effector function. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[48]  S. Schmid,et al.  Control of EGF Receptor Signaling by Clathrin-Mediated Endocytosis , 1996, Science.

[49]  A. Spradling,et al.  slow border cells, a locus required for a developmentally regulated cell migration during oogenesis, encodes Drosophila C EBP , 1992, Cell.