Mitotic catenation is monitored and resolved by a PKCε-regulated pathway

[1]  C. Hsiung,et al.  Comparative analysis of mitosis-specific antibodies for bulk purification of mitotic populations by fluorescence-activated cell sorting. , 2014, BioTechniques.

[2]  M. Lisby,et al.  TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability , 2014, The Journal of cell biology.

[3]  R. Medema,et al.  WAPL-Mediated Removal of Cohesin Protects against Segregation Errors and Aneuploidy , 2013, Current Biology.

[4]  D. J. Clarke,et al.  Direct Monitoring of the Strand Passage Reaction of DNA Topoisomerase II Triggers Checkpoint Activation , 2013, PLoS genetics.

[5]  A. Desai,et al.  Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores , 2013, The Journal of cell biology.

[6]  J. Pouwels,et al.  A ZO-1/α5β1-Integrin Complex Regulates Cytokinesis Downstream of PKCε in NCI-H460 Cells Plated on Fibronectin , 2013, PloS one.

[7]  D. Cleveland,et al.  Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20. , 2013, Molecular cell.

[8]  T. Kapoor,et al.  Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore , 2012, Nature Reviews Molecular Cell Biology.

[9]  K. Mir,et al.  DNA catenation maintains structure of human metaphase chromosomes , 2012, Nucleic acids research.

[10]  J. Shah,et al.  Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint , 2012, Chromosoma.

[11]  L. Magnaghi-Jaulin,et al.  Bloom’s Syndrome and PICH Helicases Cooperate with Topoisomerase IIα in Centromere Disjunction before Anaphase , 2012, PloS one.

[12]  G. Rummel,et al.  2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes. , 2011, Bioorganic & medicinal chemistry letters.

[13]  K. Vaughan,et al.  Zwint-1 is a novel Aurora B substrate required for the assembly of a dynein-binding platform on kinetochores , 2011, Molecular biology of the cell.

[14]  J. B. Rattner,et al.  Dynein/Dynactin-Mediated Transport of Kinetochore Components off Kinetochores and onto Spindle Poles Induced by Nordihydroguaiaretic Acid , 2011, PloS one.

[15]  G. Karaca,et al.  Topoisomerase IIα maintains genomic stability through decatenation G2 checkpoint signaling , 2010, Oncogene.

[16]  T. Hori,et al.  Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase , 2010, The Journal of cell biology.

[17]  Morten O. Christensen,et al.  Mitotic chromosomes are constrained by topoisomerase II–sensitive DNA entanglements , 2010, The Journal of cell biology.

[18]  Stephen S. Taylor,et al.  Sgo1 establishes the centromeric cohesion protection mechanism in G2 before subsequent Bub1-dependent recruitment in mitosis , 2010, Journal of Cell Science.

[19]  Benjamin A. Pinsky,et al.  Protein Phosphatase 1 Regulates Exit from the Spindle Checkpoint in Budding Yeast , 2009, Current Biology.

[20]  K. Hardwick,et al.  A Novel Protein Phosphatase 1-Dependent Spindle Checkpoint Silencing Mechanism , 2009, Current Biology.

[21]  P. Parker,et al.  Protein kinase C epsilon in cell division: Control of abscission , 2009, Cell cycle.

[22]  S. Steinberg Faculty Opinions recommendation of The regulated assembly of a PKCepsilon complex controls the completion of cytokinesis. , 2009 .

[23]  William Arbuthnot Sir Lane,et al.  Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis , 2008, The Journal of cell biology.

[24]  R. Annan,et al.  Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit , 2008, The Journal of cell biology.

[25]  M. Setou,et al.  LIS1 and NDEL1 coordinate the plus‐end‐directed transport of cytoplasmic dynein , 2008, The EMBO journal.

[26]  J. Bachant,et al.  DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint. , 2008, Molecular biology of the cell.

[27]  P. Monzo,et al.  Direct role of dynein motor in stable kinetochore-microtubule attachment, orientation, and alignment , 2008, The Journal of cell biology.

[28]  K. Nasmyth,et al.  The cohesin ring concatenates sister DNA molecules , 2008, Nature.

[29]  J. Stubbe,et al.  Mechanistic studies on bleomycin-mediated DNA damage: multiple binding modes can result in double-stranded DNA cleavage , 2008, Nucleic acids research.

[30]  M. Speicher,et al.  Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation , 2007, Chromosoma.

[31]  E. Salmon,et al.  The spindle-assembly checkpoint in space and time , 2007, Nature Reviews Molecular Cell Biology.

[32]  M. Kirschner,et al.  Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation , 2007, Nature.

[33]  K. Shokat,et al.  Chemical Genetics: Where Genetics and Pharmacology Meet , 2007, Cell.

[34]  K. Hofmann,et al.  PICH, a Centromere-Associated SNF2 Family ATPase, Is Regulated by Plk1 and Required for the Spindle Checkpoint , 2007, Cell.

[35]  T. Bestor,et al.  The decatenation checkpoint , 2007, British Journal of Cancer.

[36]  Iha Park,et al.  Cell cycle-dependent DNA damage signaling induced by ICRF-193 involves ATM, ATR, CHK2, and BRCA1. , 2006, Experimental cell research.

[37]  D. J. Clarke,et al.  A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin. , 2006, Genes & development.

[38]  Y. Toyoda,et al.  Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance. , 2006, Molecular biology of the cell.

[39]  R. Karess,et al.  Rod-Zw10-Zwilch: a key player in the spindle checkpoint. , 2005, Trends in cell biology.

[40]  T. Kitajima,et al.  Shugoshin protects cohesin complexes at centromeres , 2005, Philosophical Transactions of the Royal Society B: Biological Sciences.

[41]  Maikun Teng,et al.  Human Zwint-1 Specifies Localization of Zeste White 10 to Kinetochores and Is Essential for Mitotic Checkpoint Signaling* , 2004, Journal of Biological Chemistry.

[42]  A. Porter,et al.  Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell line. , 2004, Molecular biology of the cell.

[43]  R. Margolis,et al.  Inhibition of DNA decatenation, but not DNA damage, arrests cells at metaphase. , 2004, Molecular cell.

[44]  K. Yanagisawa,et al.  Identification of Decatenation G2 Checkpoint Impairment Independently of DNA Damage G2 Checkpoint in Human Lung Cancer Cell Lines , 2004, Cancer Research.

[45]  E. Salmon,et al.  Spindle Checkpoint Protein Dynamics at Kinetochores in Living Cells , 2004, Current Biology.

[46]  James J. Yoo,et al.  Cell cycle checkpoint function in bladder cancer. , 2003, Journal of the National Cancer Institute.

[47]  Jiri Bartek,et al.  Chk1 and Chk2 kinases in checkpoint control and cancer. , 2003, Cancer cell.

[48]  N. Akimitsu,et al.  Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIα , 2003, Genes to cells : devoted to molecular & cellular mechanisms.

[49]  A. Mikhailov,et al.  DNA Damage during Mitosis in Human Cells Delays the Metaphase/Anaphase Transition via the Spindle-Assembly Checkpoint , 2002, Current Biology.

[50]  A. Belmont Faculty Opinions recommendation of Dynamics of human DNA topoisomerases IIalpha and IIbeta in living cells. , 2002 .

[51]  A. Millar,et al.  Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability. , 2002, Cancer research.

[52]  Morten O. Christensen,et al.  Dynamics of human DNA topoisomerases IIα and IIβ in living cells , 2002, The Journal of cell biology.

[53]  E. Salmon,et al.  Cytoplasmic dynein/dynactin drives kinetochore protein transport to the spindle poles and has a role in mitotic spindle checkpoint inactivation , 2001, The Journal of cell biology.

[54]  Hanlin Gao,et al.  Topoisomerase II Poisoning by ICRF-193* , 2001, The Journal of Biological Chemistry.

[55]  S. Schwartz,et al.  Somatic mutations in the DNA damage-response genes ATR and CHK1 in sporadic stomach tumors with microsatellite instability. , 2001, Cancer research.

[56]  R. Paules,et al.  The human decatenation checkpoint , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[57]  J. Shah,et al.  Waiting for Anaphase Mad2 and the Spindle Assembly Checkpoint , 2000, Cell.

[58]  Daniel A Starr,et al.  Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores , 2000, Nature Cell Biology.

[59]  T. Kapoor,et al.  Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5 , 2000, The Journal of cell biology.

[60]  D. Gisselsson,et al.  Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[61]  M. Broggini,et al.  CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers. , 1999, Genes, chromosomes & cancer.

[62]  Friedrich Lottspeich,et al.  Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1 , 1999, Nature.

[63]  D. S. Swaffar,et al.  A unique paclitaxel-mediated modulation of the catalytic activity of topoisomerase IIalpha. , 1999, Anti-cancer drugs.

[64]  T. Andoh,et al.  ICRF‐193, a catalytic inhibitor of DNA topoisomerase II, delays the cell cycle progression from metaphase, but not from anaphase to the G1 phase in mammalian cells , 1997, FEBS letters.

[65]  C. Echeverri,et al.  Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis , 1996, The Journal of cell biology.

[66]  G. Gorbsky Cell cycle progression and chromosome segregation in mammalian cells cultured in the presence of the topoisomerase II inhibitors ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane; ADR-529] and ICRF-159 (Razoxane). , 1994, Cancer research.

[67]  B. Schaar,et al.  CENP-E is a putative kinetochore motor that accumulates just before mitosis , 1992, Nature.

[68]  D. Botstein,et al.  DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage , 1989, Molecular and cellular biology.

[69]  D. Botstein,et al.  DNA topoisomerase II is required at the time of mitosis in yeast , 1985, Cell.

[70]  D. Cimini,et al.  Topoisomerase II inhibition in mitosis produces numerical and structural chromosomal aberrations in human fibroblasts. , 1997, Cytogenetics and cell genetics.