6,8-Difluoro-4-methylumbiliferyl phosphate: a fluorogenic substrate for protein tyrosine phosphatases.

[1]  P. H. Seeburg,et al.  Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes , 1985, Nature.

[2]  E. Krebs,et al.  Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system. , 1991, Biochemistry.

[3]  C. Walsh,et al.  Purification and characterization of a soluble catalytic fragment of the human transmembrane leukocyte antigen related (LAR) protein tyrosine phosphatase from an Escherichia coli expression system. , 1991, Biochemistry.

[4]  J. C. Clemens,et al.  Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase. , 1992, The Journal of biological chemistry.

[5]  J. Dixon,et al.  A continuous spectrophotometric and fluorimetric assay for protein tyrosine phosphatase using phosphotyrosine-containing peptides. , 1993, Analytical biochemistry.

[6]  A. Ullrich,et al.  Expression, purification and crystallization of human phosphotyrosine phosphatase 1B. , 1994, European journal of biochemistry.

[7]  J. Dixon,et al.  Protein tyrosine phosphatases: mechanism of catalysis and substrate specificity. , 1994, Advances in enzymology and related areas of molecular biology.

[8]  I. Trowbridge,et al.  High level expression and purification of the enzymatically active cytoplasmic region of human CD45 phosphatase from yeast. , 1994, Biochimica et biophysica acta.

[9]  J. Noel,et al.  Structural basis for inhibition of receptor protein-tyrosine phosphatase-α by dimerization , 1996, Nature.

[10]  M. Gresser,et al.  Mechanism of Inhibition of Protein-tyrosine Phosphatases by Vanadate and Pervanadate* , 1997, The Journal of Biological Chemistry.

[11]  Z. Zhao,et al.  Expression, purification, and crystallization of the catalytic domain of protein tyrosine phosphatase SHP-1. , 1997, Journal of structural biology.

[12]  R. Haugland,et al.  Synthesis of novel fluorinated coumarins: excellent UV-light excitable fluorescent dyes. , 1998, Bioorganic & medicinal chemistry letters.

[13]  D. Barford,et al.  The structure and mechanism of protein phosphatases: insights into catalysis and regulation. , 1998, Annual review of biophysics and biomolecular structure.

[14]  Wei-Chuan Sun,et al.  Fluorogenic substrates based on fluorinated umbelliferones for continuous assays of phosphatases and beta-galactosidases. , 1999, Analytical biochemistry.

[15]  C. Ramachandran,et al.  Fluorescein monophosphates as fluorogenic substrates for protein tyrosine phosphatases. , 1999, Biochimica et biophysica acta.

[16]  M. Vieytes,et al.  A fluorescent microplate assay for microcystin-LR. , 1999, Analytical biochemistry.

[17]  R. Zamboni,et al.  3,6-Fluorescein Diphosphate: A Sensitive Fluorogenic and Chromogenic Substrate for Protein Tyrosine Phosphatases , 1999, Journal of biomolecular screening.

[18]  B. Kennedy,et al.  Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. , 1999, Science.

[19]  Young-Bum Kim,et al.  Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice , 2000, Molecular and Cellular Biology.

[20]  P G Drake,et al.  Structural and Evolutionary Relationships among Protein Tyrosine Phosphatase Domains , 2001, Molecular and Cellular Biology.

[21]  Z. Zhang,et al.  Protein tyrosine phosphatases: prospects for therapeutics. , 2001, Current opinion in chemical biology.

[22]  J. Ermolieff,et al.  Protein tyrosine phosphatase 1B inhibitors for diabetes , 2002, Nature Reviews Drug Discovery.

[23]  J. Trevillyan,et al.  Protein tyrosine phosphatase 1B as a target for the treatment of impaired glucose tolerance and type II diabetes. , 2002, Current opinion in investigational drugs.

[24]  Zhon-Yin Zhang.  Mechanistic studies on protein tyrosine phosphatases. , 2003, Progress in nucleic acid research and molecular biology.

[25]  Wayne F. Patton,et al.  Development of fluorescence-based selective assays for serine/threonine and tyrosine phosphatases. , 2003, Combinatorial chemistry & high throughput screening.