Eccentric training does not increase sarcomere number in rabbit dorsiflexor muscles.

The hypothesis of this study was that eccentric muscle training induces serial sarcomere addition. Eccentric training of rabbit dorsiflexor muscles (50 maximal contractions, 2 times per week, for 12 weeks) increased sarcomere number by only 3% in superficial fascicles of the tibialis anterior (TA) and did not change sarcomere number in deep fascicles of the TA nor in proximal or distal fascicles of extensor digitorum longus. Thus eccentric training had little or no effect on sarcomere number. These results do not support previous speculation that eccentric training produces increases in sarcomere number.

[1]  M. C. Schmitz,et al.  Anti-inflammatory medication after muscle injury. A treatment resulting in short-term improvement but subsequent loss of muscle function. , 1995, The Journal of bone and joint surgery. American volume.

[2]  D. Newham,et al.  Repeated high-force eccentric exercise: effects on muscle pain and damage. , 1987, Journal of applied physiology.

[3]  F. Booth,et al.  Skeletal muscle enlargement with weight-lifting exercise by rats. , 1988, Journal of applied physiology.

[4]  J. Faulkner,et al.  Injury to muscle fibres after single stretches of passive and maximally stimulated muscles in mice. , 1995, The Journal of physiology.

[5]  Jan Fridén,et al.  Changes in human skeletal muscle induced by long-term eccentric exercise , 2004, Cell and Tissue Research.

[6]  Timothy J. Koh,et al.  An implantable electrical interface for in vivo studies of the neuromuscular system , 1996, Journal of Neuroscience Methods.

[7]  D. Morgan New insights into the behavior of muscle during active lengthening. , 1990, Biophysical journal.

[8]  R. Armstrong,et al.  Mechanical factors in the initiation of eccentric contraction‐induced injury in rat soleus muscle. , 1993, The Journal of physiology.

[9]  J. Faulkner,et al.  Injury to Skeletal Muscle during Altitude Training: Induction and Prevention , 1992, International journal of sports medicine.

[10]  G. Goldspink,et al.  Effect of denervation on the adaptation of sarcomere number and muscle extensibility to the functional length of the muscle * , 1974, The Journal of physiology.

[11]  D. Morgan,et al.  Decline running produces more sarcomeres in rat vastus intermedius muscle fibers than does incline running. , 1994, Journal of applied physiology.

[12]  R L Lieber,et al.  Muscle cytoskeletal disruption occurs within the first 15 min of cyclic eccentric contraction. , 1996, Journal of applied physiology.

[13]  B. Davis,et al.  Adaptation to eccentric exercise: effect on CD64 and CD11b/CD18 expression. , 1996, Journal of applied physiology.

[14]  R. Meister Anti-inflammatory medication after muscle injury , 1996 .