Antimicrobial Efficacy of Silver Nanoparticles Synthesized from Withania somnifera - An Important Ethnomedicinal Herb of Kurnool District, Andhra Pradesh, India

Withania somnifera roots are extensively using by the ethnic groups of Kurnool district, Andhra Pradesh, India to cure leucoderma. Biological synthesis of silver nanoparticles was carried out from root aqueous extract of Withania somnifera 10 ml root extract was mixed to 90 ml of 1 mM aqueous of Ag(NO3)2 and was heated at 60-80 0 C for 20 min. The colour change of aqueous solution into dark brown colour. For characterization using UV-Vis spectrophotometer and AFM. AFM, UV-Vis spectrophotometer showed the formation of silver nanoparticles with spherical shape and average size 25.02 nm. SNPs have good antimicrobial activity against different microorganisms.

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