Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and CNS function
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G. Castelo-Branco | C. Vallejos | Anna C. Williams | David van Bruggen | N. Henderson | Justyna Cholewa-Waclaw | S. Jäkel | Sunniva M. K. Bøstrand | Zahra Moslehi | Luise A. Seeker | Mukund Kabbe | Nina-Lydia Kazakou | Nadine Bestard-Cuche | Gioele La Manno | A. Kilpatrick | Laura J. Wagstaff | Fabio Baldivia Pohl | L. Seeker
[1] Atique U. Ahmed,et al. Cell Lineage and Pseudotime Inference for Single-cell Transcriptomics Analysis of Chemoresistance in GBM (P11-13.002) , 2023, Wednesday, April 26.
[2] J. Saez-Rodriguez,et al. Cross-regional homeostatic and reactive glial signatures in multiple sclerosis , 2022, Acta Neuropathologica.
[3] J. Zuchero,et al. CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes , 2022, bioRxiv.
[4] O. Gokce,et al. Spatial Transcriptomics-correlated Electron Microscopy , 2022, bioRxiv.
[5] J. Wardlaw,et al. Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model , 2022, Acta Neuropathologica.
[6] K. Nave,et al. Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice , 2022, bioRxiv.
[7] J. Bourne,et al. Cholesterol biosynthesis defines oligodendrocyte precursor heterogeneity between brain and spinal cord , 2021, Cell reports.
[8] M. S. van der Knaap,et al. Heterogeneity of white matter astrocytes in the human brain , 2021, Acta Neuropathologica.
[9] S. Teichmann,et al. Differential abundance testing on single-cell data using k-nearest neighbor graphs , 2021, Nature Biotechnology.
[10] C. ffrench-Constant,et al. Oligodendrocyte HCN2 Channels Regulate Myelin Sheath Length , 2021, The Journal of Neuroscience.
[11] P. Matthews,et al. Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s pathology , 2021, bioRxiv.
[12] T. Kuhlmann,et al. SKAP2 as a new regulator of oligodendroglial migration and myelin sheath formation , 2021, bioRxiv.
[13] Bin Zhang,et al. Single-cell atlas of progressive supranuclear palsy reveals a distinct hybrid glial cell population , 2021, bioRxiv.
[14] Owen J. L. Rackham,et al. ShinyCell: simple and sharable visualization of single-cell gene expression data , 2021, Bioinform..
[15] L. Garcia-Segura,et al. Role of glial cells in the generation of sex differences in neurodegenerative diseases and brain aging , 2021, Mechanisms of Ageing and Development.
[16] Yunjiao Wang,et al. DUSP1 Promotes Microglial Polarization toward M2 Phenotype in the Medial Prefrontal Cortex of Neuropathic Pain Rats via Inhibition of MAPK Pathway. , 2021, ACS chemical neuroscience.
[17] F. Tang,et al. Heterogeneity of glial progenitor cells during the neurogenesis-to-gliogenesis switch in the developing human cerebral cortex. , 2021, Cell reports.
[18] Hongyu Guo,et al. scSorter: assigning cells to known cell types according to marker genes , 2021, Genome biology.
[19] J. Mulder,et al. Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease , 2021, Acta Neuropathologica.
[20] Kira E. Poskanzer,et al. Reactive astrocyte nomenclature, definitions, and future directions , 2021, Nature Neuroscience.
[21] M. Simons,et al. White matter aging drives microglial diversity , 2021, Neuron.
[22] Anna C. Williams,et al. Oligodendroglial Heterogeneity in Neuropsychiatric Disease , 2021, Life.
[23] B. Becher,et al. Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes , 2021, Nature.
[24] A. Kriegstein,et al. Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia , 2020, Nature Neuroscience.
[25] Markus M. Hilscher,et al. Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury , 2020, Nature Communications.
[26] P. Matthews,et al. Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans , 2020, Cell reports.
[27] A. Kriegstein,et al. Origins and Proliferative States of Human Oligodendrocyte Precursor Cells , 2020, Cell.
[28] R. Takahashi,et al. Sex-specific differences in transcriptomic profiles and cellular characteristics of oligodendrocyte precursor cells. , 2020, Stem cell research.
[29] J. Ragoussis,et al. Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons , 2020, Nature Neuroscience.
[30] J. González,et al. Extreme downregulation of chromosome Y and Alzheimer's disease in men , 2020, Neurobiology of Aging.
[31] Maxim N. Artyomov,et al. Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and - independent cellular responses in Alzheimer’s disease , 2019, Nature Medicine.
[32] R. Franklin,et al. Remyelination and ageing: Reversing the ravages of time , 2019, Multiple sclerosis.
[33] Fabian J Theis,et al. Generalizing RNA velocity to transient cell states through dynamical modeling , 2019, Nature Biotechnology.
[34] S. Dietmann,et al. Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells , 2019, Cell stem cell.
[35] L. Gan,et al. Do Microglial Sex Differences Contribute to Sex Differences in Neurodegenerative Diseases? , 2019, Trends in molecular medicine.
[36] D. Rowitch,et al. Niche stiffness underlies the aging of central nervous system progenitor cells , 2019, Nature.
[37] Richard Reynolds,et al. Neuronal vulnerability and multilineage diversity in multiple sclerosis , 2019, Nature.
[38] Manolis Kellis,et al. Single-cell transcriptomic analysis of Alzheimer’s disease , 2019, Nature.
[39] Yvan Saeys,et al. A comparison of single-cell trajectory inference methods , 2019, Nature Biotechnology.
[40] S. Dietmann,et al. Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age , 2019, Neuron.
[41] D. Malhotra,et al. Altered human oligodendrocyte heterogeneity in multiple sclerosis , 2019, Nature.
[42] S. Bernard,et al. Dynamics of oligodendrocyte generation in multiple sclerosis , 2019, Nature.
[43] J. Satoh,et al. Microglia express GPNMB in the brains of Alzheimer's disease and Nasu-Hakola disease. , 2019, Intractable & rare diseases research.
[44] Sueli Marques,et al. Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis , 2018, Nature Medicine.
[45] Xuanmao Chen,et al. Neuronal and astrocytic primary cilia in the mature brain , 2018, Pharmacological research.
[46] Åsa K. Björklund,et al. Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development , 2018, Developmental cell.
[47] Erik Sundström,et al. RNA velocity of single cells , 2018, Nature.
[48] Lars E. Borm,et al. Molecular Architecture of the Mouse Nervous System , 2018, Cell.
[49] A. Goate,et al. Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease , 2018, bioRxiv.
[50] Paul Hoffman,et al. Integrating single-cell transcriptomic data across different conditions, technologies, and species , 2018, Nature Biotechnology.
[51] Jie Qiao,et al. A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex , 2018, Nature.
[52] J. Grutzendler,et al. Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain , 2018, Nature Neuroscience.
[53] Li Li,et al. Massively Parallel Single Nucleus Transcriptional Profiling Defines Spinal Cord Neurons and Their Activity during Behavior , 2018, Cell reports.
[54] Ben A. Barres,et al. Normal aging induces A1-like astrocyte reactivity , 2018, Proceedings of the National Academy of Sciences.
[55] J. Morris,et al. Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease , 2018, bioRxiv.
[56] Emilia Favuzzi,et al. Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican , 2017, Neuron.
[57] I. Scarisbrick,et al. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination , 2017, PloS one.
[58] Russell B. Fletcher,et al. Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics , 2017, bioRxiv.
[59] Nadine C. Heyworth,et al. Microglia activation and phagocytosis: relationship with aging and cognitive impairment in the rhesus monkey , 2017, GeroScience.
[60] Manoj Kumar,et al. INGE GRUNDKE-IQBAL AWARD FOR ALZHEIMER’S RESEARCH: NEUROTOXIC REACTIVE ASTROCYTES ARE INDUCED BY ACTIVATED MICROGLIA , 2019, Alzheimer's & Dementia.
[61] Peter Bankhead,et al. QuPath: Open source software for digital pathology image analysis , 2017, Scientific Reports.
[62] J. Ule,et al. Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging , 2017, Cell reports.
[63] F. Benfenati,et al. The Transcription Factors EBF1 and EBF2 Are Positive Regulators of Myelination in Schwann Cells , 2017, Molecular Neurobiology.
[64] Paul J. Lucassen,et al. The Indispensable Roles of Microglia and Astrocytes during Brain Development , 2016, Front. Hum. Neurosci..
[65] Davis J. McCarthy,et al. A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor , 2016, F1000Research.
[66] Aaron T. L. Lun,et al. Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R , 2017, Bioinform..
[67] Jens Hjerling-Leffler,et al. Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system , 2016, Science.
[68] W. Richardson,et al. Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline , 2016, Cell reports.
[69] J. Bilezikian,et al. Primary Hyperparathyroidism , 2016, F1000Research.
[70] C. ffrench-Constant,et al. CNS Myelin Sheath Lengths Are an Intrinsic Property of Oligodendrocytes , 2015, Current Biology.
[71] Carlos Matute,et al. Pío del Río Hortega and the discovery of the oligodendrocytes , 2015, Front. Neuroanat..
[72] P. Linsley,et al. MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data , 2015, Genome Biology.
[73] S. Quake,et al. A survey of human brain transcriptome diversity at the single cell level , 2015, Proceedings of the National Academy of Sciences.
[74] Peter J. Mohler,et al. GLIAL ANKYRINS FACILITATE PARANODAL AXOGLIAL JUNCTION ASSEMBLY , 2014, Nature Neuroscience.
[75] J. Antel,et al. Heterogeneity of oligodendrocyte progenitor cells in adult human brain , 2014, Annals of clinical and translational neurology.
[76] Cole Trapnell,et al. The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells , 2014, Nature Biotechnology.
[77] Cole Trapnell,et al. Pseudo-temporal ordering of individual cells reveals dynamics and regulators of cell fate decisions , 2014, Nature Biotechnology.
[78] J. Lechner-Scott,et al. Sex as a determinant of relapse incidence and progressive course of multiple sclerosis. , 2013, Brain : a journal of neurology.
[79] M. Götz,et al. Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain , 2013, Nature Neuroscience.
[80] Guangchuang Yu,et al. clusterProfiler: an R package for comparing biological themes among gene clusters. , 2012, Omics : a journal of integrative biology.
[81] M Daumer,et al. Age and disability accumulation in multiple sclerosis , 2011, Neurology.
[82] S. Whittemore,et al. Dorsally‐derived oligodendrocytes in the spinal cord contribute to axonal myelination during development and remyelination following focal demyelination , 2011, Glia.
[83] P. Sørensen,et al. Demyelination versus remyelination in progressive multiple sclerosis. , 2010, Brain : a journal of neurology.
[84] E. Birney,et al. Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt , 2009, Nature Protocols.
[85] N. Zečević,et al. Oligodendrocyte Development and the Onset of Myelination in the Human Fetal Brain , 2009, Front. Neuroanat..
[86] Tsutomu Hashikawa,et al. Opalin, a Transmembrane Sialylglycoprotein Located in the Central Nervous System Myelin Paranodal Loop Membrane* , 2008, Journal of Biological Chemistry.
[87] H. Kettenmann,et al. Microglia: active sensor and versatile effector cells in the normal and pathologic brain , 2007, Nature Neuroscience.
[88] Rafael Arroyo,et al. Early B-cell Factor gene association with multiple sclerosis in the Spanish population , 2005, BMC neurology.
[89] Hilde van der Togt,et al. Publisher's Note , 2003, J. Netw. Comput. Appl..
[90] Chao Zhao,et al. The Age-Related Decrease in CNS Remyelination Efficiency Is Attributable to an Impairment of Both Oligodendrocyte Progenitor Recruitment and Differentiation , 2002, The Journal of Neuroscience.
[91] R. Krumlauf,et al. Regulatory analysis of the mouse Hoxb3 gene: multiple elements work in concert to direct temporal and spatial patterns of expression. , 2001, Developmental biology.
[92] B. Ye,et al. unc-3, a gene required for axonal guidance in Caenorhabditis elegans, encodes a member of the O/E family of transcription factors. , 1998, Development.
[93] S. Xuan,et al. Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres , 1995, Neuron.