Positive and negative regulation of T-cell activation through kinases and phosphatases.
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[1] J. Chen,et al. Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development. , 2001, Blood.
[2] A. Shaw,et al. Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[3] D. Carrasco,et al. Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts. , 1996, Oncogene.
[4] Matthew L. Thomas,et al. Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation , 1989, Cell.
[5] P. Dráber,et al. Thy-1 glycoprotein and src-like protein-tyrosine kinase p53/p56lyn are associated in large detergent-resistant complexes in rat basophilic leukemia cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[6] N. Abraham,et al. Activation of p56lck through mutation of a regulatory carboxy-terminal tyrosine residue requires intact sites of autophosphorylation and myristylation , 1990, Molecular and cellular biology.
[7] A. Bothwell,et al. Deficient expression of p56(lck) in Th2 cells leads to partial TCR signaling and a dysregulation in lymphokine mRNA levels. , 1996, Journal of immunology.
[8] M. Streuli,et al. Specific interaction of the CD45 protein-tyrosine phosphatase with tyrosine-phosphorylated CD3 zeta chain. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[9] T. Mustelin,et al. Negative Regulation of T Cell Antigen Receptor Signal Transduction by Hematopoietic Tyrosine Phosphatase (HePTP)* , 1998, The Journal of Biological Chemistry.
[10] M. Yaffe,et al. Biochemical Interactions Integrating Itk with the T Cell Receptor-initiated Signaling Cascade* , 2000, The Journal of Biological Chemistry.
[11] Hiroto Yamaguchi,et al. Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation , 1996, Nature.
[12] T. Mustelin,et al. Inhibition of T Cell Signaling by Mitogen-activated Protein Kinase-targeted Hematopoietic Tyrosine Phosphatase (HePTP)* , 1999, The Journal of Biological Chemistry.
[13] A. Alonso,et al. Protein tyrosine phosphorylation in T cell signaling. , 2002, Frontiers in bioscience : a journal and virtual library.
[14] J. Hardwick,et al. Activation of the Lck tyrosine protein kinase by hydrogen peroxide requires the phosphorylation of Tyr-394. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[15] W. Rodgers,et al. Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction , 1994, Molecular and cellular biology.
[16] K. Amrein,et al. Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblasts. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[17] J. Cambier,et al. Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases. , 1995, Journal of immunology.
[18] R. Abraham,et al. Signal transduction through the T-cell antigen receptor. , 1992, Trends in biochemical sciences.
[19] Sheraz Yaqub,et al. Release from Tonic Inhibition of T Cell Activation through Transient Displacement of C-terminal Src Kinase (Csk) from Lipid Rafts* , 2001, The Journal of Biological Chemistry.
[20] M. Lisanti,et al. Regulation of cAMP-mediated Signal Transduction via Interaction of Caveolins with the Catalytic Subunit of Protein Kinase A* , 1999, The Journal of Biological Chemistry.
[21] R. Sékaly,et al. Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the αβ T-cell receptor , 1992, Nature.
[22] T. Mustelin,et al. Do CD4 and CD8 control T-cell activation via a specific tyrosine protein kinase? , 1989, Immunology today.
[23] Michael J. Eck,et al. Three-dimensional structure of the tyrosine kinase c-Src , 1997, Nature.
[24] R. Johnson,et al. Activation of ZAP‐70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. , 1995, The EMBO journal.
[25] A. Weiss,et al. CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. , 1993, The EMBO journal.
[26] R. Aebersold,et al. ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity , 1995, The Journal of experimental medicine.
[27] H. Turner,et al. A Comparison of the Interaction of Shc and the Tyrosine Kinase ZAP-70 with the T Cell Antigen Receptor ζ Chain Tyrosine-based Activation Motif (*) , 1995, The Journal of Biological Chemistry.
[28] Philippe Soriano,et al. Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice , 1993, Cell.
[29] L. Samelson,et al. LAT The ZAP-70 Tyrosine Kinase Substrate that Links T Cell Receptor to Cellular Activation , 1998, Cell.
[30] Paul M. Allen,et al. Partial T cell signaling: Altered phospho-ζ and lack of zap70 recruitment in APL-induced T cell anergy , 1994, Cell.
[31] B. Howell,et al. Csk suppression of Src involves movement of Csk to sites of Src activity , 1994, Molecular and cellular biology.
[32] A. Veillette,et al. PTP‐PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates , 2001, The EMBO journal.
[33] J. Imboden,et al. Molecular Cloning of the cDNA Encoding pp36, a Tyrosine-phosphorylated Adaptor Protein Selectively Expressed by T Cells and Natural Killer Cells , 1998, The Journal of experimental medicine.
[34] T. Mustelin,et al. Extracellular signals and scores of phosphatases: all roads lead to MAP kinase. , 2000, Seminars in immunology.
[35] Heather M. Wilcox,et al. Lck Phosphorylates the Activation Loop Tyrosine of the Itk Kinase Domain and Activates Itk Kinase Activity* , 1997, The Journal of Biological Chemistry.
[36] Michael A. Bookman,et al. The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56 lck , 1988, Cell.
[37] A. Gilman,et al. Organization of G proteins and adenylyl cyclase at the plasma membrane. , 1997, Molecular biology of the cell.
[38] T. Mustelin,et al. Dephosphorylation of ZAP‐70 and inhibition of T cell activation by activated SHP1 , 1999, European journal of immunology.
[39] T. Yamamoto,et al. CSK: a protein-tyrosine kinase involved in regulation of src family kinases. , 1991, The Journal of biological chemistry.
[40] M. Amiot,et al. Sequence requirements for induction of cytolysis by the T cell antigen Fc receptor ζ chain , 1992, Cell.
[41] M. Miyazaki,et al. Cutting Edge: Negative Regulation of Immune Synapse Formation by Anchoring Lipid Raft to Cytoskeleton Through Cbp-EBP50-ERM Assembly1 , 2002, The Journal of Immunology.
[42] R. Abraham,et al. Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events. , 1993, The Journal of biological chemistry.
[43] D. Alexander,et al. Differential Association of CD45 Isoforms with CD4 and CD8 Regulates the Actions of Specific Pools of p56lck Tyrosine Kinase in T Cell Antigen Receptor Signal Transduction* , 2002, The Journal of Biological Chemistry.
[44] R. Majeti,et al. An Inactivating Point Mutation in the Inhibitory Wedge of CD45 Causes Lymphoproliferation and Autoimmunity , 2000, Cell.
[45] E. Shaoul,et al. Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp. , 1999, Blood.
[46] Y. Takayama,et al. Transmembrane Phosphoprotein Cbp Positively Regulates the Activity of the Carboxyl-terminal Src Kinase, Csk* , 2000, The Journal of Biological Chemistry.
[47] G. Kammer. The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response. , 1988, Immunology today.
[48] T. Mustelin,et al. Regulation of src family tyrosine kinases in lymphocytes. , 1993, Trends in biochemical sciences.
[49] A. Shaw,et al. Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[50] A. Veillette,et al. Differential Intrinsic Enzymatic Activity of Syk and Zap-70 Protein-tyrosine Kinases* , 1996, The Journal of Biological Chemistry.
[51] G. Schieven,et al. Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[52] F. Emmrich,et al. Cross-linking of CD4 and CD8 with the T-cell receptor complex: quaternary complex formation and T-cell repertoire selection. , 1988, Immunology today.
[53] C. June,et al. The CD45 tyrosine phosphatase regulates phosphotyrosine homeostasis and its loss reveals a novel pattern of late T cell receptor-induced Ca2+ oscillations , 1992, The Journal of experimental medicine.
[54] Jonathan A. Cooper,et al. Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src , 1991, Nature.
[55] T. Mustelin,et al. Cytoskeletal protein tyrosine phosphatase PTPH1 reduces T cell antigen receptor signaling , 2000, European journal of immunology.
[56] B. Zanke,et al. Hematopoietic Protein Tyrosine Phosphatase Suppresses Extracellular Stimulus-Regulated Kinase Activation , 2001, Molecular and Cellular Biology.
[57] E. Krebs,et al. Regulation of pp56lck during T‐cell activation: functional implications for the src‐like protein tyrosine kinases. , 1987, The EMBO journal.
[58] T. Pawson,et al. The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[59] A. Weiss,et al. The protein tyrosine kinase ZAP-70 can associate with the SH2 domain of proto-Vav. , 1994, The Journal of biological chemistry.
[60] S. Ley,et al. Cholesterol depletion disrupts lipid rafts and modulates the activity of multiple signaling pathways in T lymphocytes , 2000, European journal of immunology.
[61] V. Hořejší,et al. The nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinases. , 1992, Journal of immunology.
[62] R. Klausner,et al. T cell antigen receptor activation pathways: The tyrosine kinase connection , 1991, Cell.
[63] M. Reth,et al. Interaction of SLP adaptors with the SH2 domain of Tec family kinases , 1999, European journal of immunology.
[64] H. Huitfeldt,et al. Location of cAMP-dependent protein kinase type I with the TCR-CD3 complex. , 1994, Science.
[65] B. Seed,et al. T cell activation by clustered tyrosine kinases , 1993, Cell.
[66] T. Mustelin,et al. Regulation of the p59fyn protein tyrosine kinase by the CD45 phosphotyrosine phosphatase , 1992, European journal of immunology.
[67] J. Noel,et al. Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge. , 1998, Science.
[68] A. Alonso,et al. Protein tyrosine phosphatases. , 2002, Frontiers in bioscience : a journal and virtual library.
[69] Dan R. Littman,et al. Signal transduction by lymphocyte antigen receptors , 1994, Cell.
[70] J. O’Shea,et al. Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[71] A. Cohen,et al. Defective T cell receptor signaling and CD8+ thymic selection in humans lacking Zap-70 kinase , 1994, Cell.
[72] Tomas Mustelin,et al. Activation of the Cooh-Terminal Src Kinase (Csk) by Camp-Dependent Protein Kinase Inhibits Signaling through the T Cell Receptor , 2001, The Journal of experimental medicine.
[73] K. Ching,et al. TCR/CD3-Induced Activation and Binding of Emt/Itk to Linker of Activated T Cell Complexes: Requirement for the Src Homology 2 Domain1 , 2000, The Journal of Immunology.
[74] T. Mustelin,et al. Induction of hyperphosphorylation and activation of the p56lck protein tyrosine kinase by phenylarsine oxide, a phosphotyrosine phosphatase inhibitor. , 1994, Molecular immunology.
[75] T. Pawson,et al. Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[76] Sefton Bm. The lck tyrosine protein kinase. , 1991 .
[77] A. Levine,et al. Lipid Raft Heterogeneity in Human Peripheral Blood T Lymphoblasts: A Mechanism for Regulating the Initiation of TCR Signal Transduction1 , 2002, The Journal of Immunology.
[78] Arthur Weiss,et al. The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways , 1991, Cell.
[79] N. Tonks,et al. Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST , 1996, Molecular and cellular biology.
[80] C. Rudd,et al. The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[81] J. Cloutier,et al. Cooperative Inhibition of T-Cell Antigen Receptor Signaling by a Complex between a Kinase and a Phosphatase , 1999, The Journal of experimental medicine.
[82] T. Mustelin. Src family tyrosine kinases in leukocytes , 1994 .
[83] Jonathan A. Cooper,et al. Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck) , 1988, Molecular and cellular biology.
[84] P. Johnson,et al. Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[85] T. Pawson,et al. Regulation of c-Src tyrosine kinase activity by the Src SH2 domain. , 1993, Oncogene.
[86] K. Sugamura,et al. Involvement of Lat, Gads, and Grb2 in Compartmentation of Slp-76 to the Plasma Membrane , 2000, The Journal of experimental medicine.
[87] G. Feng. Shp-2 tyrosine phosphatase: signaling one cell or many. , 1999, Experimental cell research.
[88] S. Kanner,et al. Regulated association between the tyrosine kinase Emt/Itk/Tsk and phospholipase-C gamma 1 in human T lymphocytes. , 1999, Journal of immunology.
[89] Sefton Bm,et al. Analysis of the activity and phosphorylation of the lck protein in lymphoid cells. , 1989 .
[90] Human placenta protein-tyrosine-phosphatase: amino acid sequence and relationship to a family of receptor-like proteins , 1989 .
[91] Victor L. J. Tybulewicz,et al. Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk , 1995, Nature.
[92] E. Aandahl,et al. Protein kinase A type I antagonist restores immune responses of T cells from HIV‐infected patients , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[93] K. Siminovitch,et al. Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase , 1996, The Journal of experimental medicine.
[94] J. Cloutier,et al. Association of inhibitory tyrosine protein kinase p50csk with protein tyrosine phosphatase PEP in T cells and other hemopoietic cells. , 1996, The EMBO journal.
[95] T. Mustelin. T cell antigen receptor signaling: three families of tyrosine kinases and a phosphatase. , 1994, Immunity.
[96] T. Mustelin,et al. Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[97] C. Rudd,et al. The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[98] A. Weiss,et al. Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms , 2002, Nature Immunology.
[99] H. Grey,et al. Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses. , 1997, Journal of immunology.
[100] T. Mustelin,et al. Inhibitory Role for Dual Specificity Phosphatase VHR in T Cell Antigen Receptor and CD28-induced Erk and Jnk Activation* , 2001, The Journal of Biological Chemistry.
[101] Naděžda Brdičková,et al. Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton , 2001, FEBS letters.
[102] J. Cloutier,et al. Inhibitory Tyrosine Protein Kinase p50 csk Is Associated with Protein-tyrosine Phosphatase PTP-PEST in Hemopoietic and Non-hemopoietic Cells* , 1997, The Journal of Biological Chemistry.
[103] A. Weiss,et al. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. , 1994, Journal of immunology.
[104] J. R. Weber,et al. Association of the tyrosine kinase LCK with phospholipase C-gamma 1 after stimulation of the T cell antigen receptor , 1992, The Journal of experimental medicine.
[105] Tomas Mustelin,et al. Characterization of TCR‐induced receptor‐proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP , 1999, European journal of immunology.
[106] R. Abraham,et al. Genetic Evidence for Differential Coupling of Syk Family Kinases to the T-Cell Receptor: Reconstitution Studies in a ZAP-70-Deficient Jurkat T-Cell Line , 1998, Molecular and Cellular Biology.
[107] J. Partanen,et al. cyl encodes a putative cytoplasmic tyrosine kinase lacking the conserved tyrosine autophosphorylation site (Y416src). , 1991, Oncogene.
[108] T. Mustelin,et al. Molecular events mediating T cell activation. , 1990, Advances in immunology.
[109] G. Mills,et al. Functional LCK Is Required for Optimal CD28-mediated Activation of the TEC Family Tyrosine Kinase EMT/ITK (*) , 1996, The Journal of Biological Chemistry.
[110] A. Nel,et al. The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase. Evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant. , 1994, The Journal of biological chemistry.
[111] R. Kobayashi,et al. Identification of the Cell Cycle Regulator VCP (p97/CDC48) as a Substrate of the Band 4.1-related Protein-tyrosine Phosphatase PTPH1* , 1999, The Journal of Biological Chemistry.
[112] A. Godzik,et al. Inhibition of T Cell Antigen Receptor Signaling by VHR-related MKPX (VHX), a New Dual Specificity Phosphatase Related to VH1 Related (VHR)* , 2002, The Journal of Biological Chemistry.
[113] H. Ostergaard,et al. Dynamic Association of CD45 with Detergent-Insoluble Microdomains in T Lymphocytes1 , 2002, The Journal of Immunology.
[114] R. Klausner,et al. Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[115] Tony Pawson,et al. Syk tyrosine kinase required for mouse viability and B-cell development , 1995, Nature.
[116] A. Viola,et al. The amplification of TCR signaling by dynamic membrane microdomains. , 2001, Trends in immunology.
[117] M. Thomas,et al. Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences , 1992, Molecular and cellular biology.
[118] T. Mustelin. Keeping the T-cell immune response in balance: role of protein tyrosine phosphatases in autoimmunity. , 2002, Current directions in autoimmunity.
[119] T. Mustelin,et al. Arginine Methylation of STAT1 Regulates Its Dephosphorylation by T Cell Protein Tyrosine Phosphatase* , 2002, The Journal of Biological Chemistry.
[120] M. Thomas,et al. The leukocyte common antigen family. , 1989, Annual review of immunology.
[121] John Kuriyan,et al. Crystal structure of the Src family tyrosine kinase Hck , 1997, Nature.
[122] Kenneth G. Johnson,et al. Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling , 2002, European journal of immunology.
[123] S. Aaronson,et al. Acquisition of transforming properties by FYN, a normal SRC-related human gene. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[124] Toshifumi Takao,et al. Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases , 2000, Nature.
[125] R. Abraham,et al. Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line. , 1999, International immunology.
[126] S. Bunnell,et al. T Cell Receptor–initiated Calcium Release Is Uncoupled from Capacitative Calcium Entry in Itk-deficient T Cells , 1998, The Journal of experimental medicine.
[127] J. Ashwell,et al. Cutting edge: the CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes. , 1999, Journal of immunology.
[128] T. Mustelin,et al. T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation. , 1990, Science.
[129] D. Zaller,et al. Staging and resetting T cell activation in SMACs , 2002, Nature Immunology.
[130] K. Nakayama,et al. Essential role for ZAP-70 in both positive and negative selection of thymocytes , 1995, Nature.
[131] M. Peter,et al. Association of phosphatidylinositol 3-kinase with a specific sequence of the T cell receptor zeta chain is dependent on T cell activation. , 1994, The Journal of biological chemistry.
[132] Josef M. Penninger,et al. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling , 2001, Nature.
[133] T. Mustelin,et al. Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk. , 1997, European journal of biochemistry.
[134] J. C. Pratt,et al. Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation. , 1998, Molecular cell.
[135] K. Torgersen,et al. Molecular mechanisms for protein kinase A-mediated modulation of immune function. , 2002, Cellular signalling.
[136] É. Vivier,et al. Immunoreceptor Tyrosine-based Inhibition Motifs , 2012, Current Topics in Microbiology and Immunology.
[137] H. Schneider,et al. Resting Lymphocyte Kinase (Rlk/Txk) Targets Lymphoid Adaptor SLP-76 in the Cooperative Activation of Interleukin-2 Transcription in T-cells* , 2000, The Journal of Biological Chemistry.
[138] T. Yagi,et al. Constitutive activation of Src family kinases in mouse embryos that lack Csk , 1993, Cell.
[139] T. Mustelin,et al. Dephosphorylation and activation of the T cell tyrosine kinase pp56lck by the leukocyte common antigen (CD45). , 1990, Oncogene.
[140] S. Kanner,et al. CD45 modulates T cell receptor/CD3‐induced activation of human thymocytes via regulation of tyrosine phosphorylation , 1992, European journal of immunology.
[141] M. Fournel,et al. The CD4 associated tyrosine protein kinase p56lck is positively regulated through its site of autophosphorylation. , 1990, Oncogene.
[142] Arthur Weiss,et al. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor , 1992, Cell.
[143] D. Alexander,et al. CD45 tyrosine phosphatase‐activated p59fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influx. , 1992, The EMBO journal.
[144] M. Tremblay,et al. Combination of gene targeting and substrate trapping to identify substrates of protein tyrosine phosphatases using PTP-PEST as a model. , 1998, Biochemistry.
[145] W. Kuo,et al. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. , 1994, Science.
[146] T. Hope,et al. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. , 1994, Science.
[147] P. W. Janes,et al. The role of lipid rafts in T cell antigen receptor (TCR) signalling. , 2000, Seminars in immunology.
[148] A. Weiss,et al. Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway , 1990, Nature.
[149] D. E. Bauer,et al. Recruitment of Slp-76 to the Membrane and Glycolipid-Enriched Membrane Microdomains Replaces the Requirement for Linker for Activation of T Cells in T Cell Receptor Signaling , 2000, The Journal of experimental medicine.
[150] S. Døskeland,et al. Cyclic AMP-dependent protein kinase type I mediates the inhibitory effects of 3',5'-cyclic adenosine monophosphate on cell replication in human T lymphocytes. , 1992, The Journal of biological chemistry.
[151] T. Hirano,et al. Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors. , 1999, Blood.
[152] T. Mustelin,et al. Regulation of the Low Molecular Weight Phosphotyrosine Phosphatase by Phosphorylation at Tyrosines 131 and 132* , 1997, The Journal of Biological Chemistry.
[153] Karel Drbal,et al. Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation , 2000, The Journal of experimental medicine.
[154] C. Turck,et al. Molecular Cloning of SLP-76, a 76-kDa Tyrosine Phosphoprotein Associated with Grb2 in T Cells (*) , 1995, The Journal of Biological Chemistry.
[155] B. Druker,et al. VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation. , 1992, The EMBO journal.
[156] A. Shaw,et al. Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins , 1995, Molecular and cellular biology.
[157] A. Alonso,et al. Activation of ZAP-70 through Specific Dephosphorylation at the Inhibitory Tyr-292 by the Low Molecular Weight Phosphotyrosine Phosphatase (LMPTP)* , 2002, The Journal of Biological Chemistry.
[158] T. Mustelin,et al. Phosphotyrosine phosphatases are involved in reversion of T lymphoblastic proliferation , 1990, European journal of immunology.
[159] R. Aebersold,et al. Activating and Inhibitory Mutations in Adjacent Tyrosines in the Kinase Domain of ZAP-70 (*) , 1995, The Journal of Biological Chemistry.
[160] L. Samelson,et al. Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists , 1995, Science.
[161] A. Barclay,et al. The association of the protein tyrosine kinases p56lck and p60fyn with the glycosyl phosphatidylinositol‐anchored proteins Thy‐1 and CD48 in rat thymocytes is dependent on the state of cellular activation , 1993, European journal of immunology.
[162] L. Samelson,et al. T cell antigen-receptor signal transduction. , 1999, Current opinion in immunology.