Effectiveness of Cold Therapy in Reducing Post-Surgery Oedema, Pain and Trismus after Impacted Mandibular Third Molar Surgery: A Randomized Observer-Blind Split-Mouth Clinical Trial

Pain, swelling, and trismus are the most common undesirable effects seen in the post-op period after impacted mandibular third molar surgeries. To prevent these effects different methods of treatment has been advocated from time to time. Cold therapy is one of the conventional methods used for reducing these undesirable effects after dentoalveolar surgeries. However, there is a lack of knowledge about its effectiveness to prevent these post-op sequelae. This study was aimed to evaluate the effects of local cold application therapy in reducing pain, trismus, and swelling after impacted mandibular third molar surgery. 18 patients (7 males and 11 females) with bilaterally placed symmetrical mandibular impacted third molars were enrolled in this randomized, observer-blind split-mouth clinical trial. The patients were aged between 18-65 years. After surgical removal of the tooth on one side (intervention), ice pack therapy was given for 24 h after surgery; and for the other side (control), no cold therapy was advised. The time interval between the two surgeries was at least 4 weeks and the amount of trismus and facial swelling was measured on day 2 and 7 postoperatively. The pain was measured by VAS scale on day 1, 2, and 7 postoperatively. The amount of pain, and trismus, were not significantly different between the intervention and control sides but the swelling was less with cold therapy. Thus, Cold therapy had some beneficial effects on postoperative swelling, with no effect on pain and trismus after impacted mandibular third molar surgery.

[1]  G. R. Bayar,et al.  Clinical comparison of submucosal injection of dexamethasone and triamcinolone acetonide on postoperative discomfort after third molar surgery. , 2015, Quintessence international.

[2]  C. Frampton,et al.  Combination paracetamol and ibuprofen for pain relief after oral surgery: a dose ranging study , 2015, European Journal of Clinical Pharmacology.

[3]  B. Augustyńska,et al.  The Effect of Submaximal Exercise Preceded by Single Whole-Body Cryotherapy on the Markers of Oxidative Stress and Inflammation in Blood of Volleyball Players , 2013, Oxidative medicine and cellular longevity.

[4]  R. Rullo,et al.  Piezoelectric device vs. conventional rotative instruments in impacted third molar surgery: relationships between surgical difficulty and postoperative pain with histological evaluations. , 2013, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.

[5]  M. Rana,et al.  Three-dimensional evaluation of postoperative swelling after third molar surgery using 2 different cooling therapy methods: a randomized observer-blind prospective study. , 2011, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[6]  I. Harris,et al.  Cryotherapy after total knee arthroplasty a systematic review and meta-analysis of randomized controlled trials. , 2010, The Journal of arthroplasty.

[7]  T. Forouzanfar,et al.  Effect of ice compression on pain after mandibular third molar surgery: a single-blind, randomized controlled trial. , 2008, International journal of oral and maxillofacial surgery.

[8]  M. Zandi Comparison of corticosteroids and rubber drain for reduction of sequelae after third molar surgery , 2008, Oral and Maxillofacial Surgery.

[9]  T. Al-Khateeb,et al.  Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus after surgical extraction of mandibular third molars. , 2008, International journal of oral and maxillofacial surgery.

[10]  S. Resch,et al.  Postoperative cryotherapy after total knee arthroplasty: a prospective study of 86 patients. , 2006, The Journal of arthroplasty.

[11]  M. Gabriele,et al.  Perioperative dexamethasone reduces post-surgical sequelae of wisdom tooth removal. A split-mouth randomized double-masked clinical trial. , 2006, International journal of oral and maxillofacial surgery.

[12]  J. R. Laureano Filho,et al.  The influence of cryotherapy on reduction of swelling, pain and trismus after third-molar extraction: a preliminary study. , 2005, Journal of the American Dental Association.

[13]  P. Becker,et al.  A randomized observer blind comparison of bilateral facial ice pack therapy with no ice therapy following third molar surgery. , 2005, International journal of oral and maxillofacial surgery.

[14]  R. Pietrobon,et al.  Cryotherapy After ACL Reconstruction – A Meta-analysis , 2005, The journal of knee surgery.

[15]  T. Macfarlane,et al.  A double-blind randomised controlled clinical trial of the effect of preoperative ibuprofen, diclofenac, paracetamol with codeine and placebo tablets for relief of postoperative pain after removal of impacted third molars. , 2004, The British journal of oral & maxillofacial surgery.

[16]  Scott F Nadler,et al.  The physiologic basis and clinical applications of cryotherapy and thermotherapy for the pain practitioner. , 2004, Pain physician.

[17]  S. McDonough,et al.  The Use of Ice in the Treatment of Acute Soft-Tissue Injury , 2004, American Journal of Sports Medicine.

[18]  H. Precheur,et al.  An open-label evaluation of the efficacy and safety of Stadol NS with ibuprofen in the treatment of pain after removal of impacted wisdom teeth. , 2000, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[19]  U. Sinterhauf,et al.  A Placebo‐Controlled Comparative Evaluation of Diclofenac Dispersible Versus Ibuprofen in Postoperative Pain After Third Molar Surgery , 1994, Journal of clinical pharmacology.

[20]  B. Lilja,et al.  The effect of local cold application on intramuscular blood flow at rest and after running. , 1985, Medicine and science in sports and exercise.

[21]  Shuai Chen,et al.  Effect of cryotherapy after elbow arthrolysis: a prospective, single-blinded, randomized controlled study. , 2015, Archives of physical medicine and rehabilitation.

[22]  Y. Nusair Local application of ice bags did not affect postoperative facial swelling after oral surgery in rabbits. , 2007, The British journal of oral & maxillofacial surgery.